KEGG   Mandrillus leucophaeus (drill): 105554734
Entry
105554734         CDS       T08763                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu01522  Endocrine resistance
mleu04010  MAPK signaling pathway
mleu04012  ErbB signaling pathway
mleu04014  Ras signaling pathway
mleu04024  cAMP signaling pathway
mleu04068  FoxO signaling pathway
mleu04071  Sphingolipid signaling pathway
mleu04137  Mitophagy - animal
mleu04140  Autophagy - animal
mleu04141  Protein processing in endoplasmic reticulum
mleu04210  Apoptosis
mleu04215  Apoptosis - multiple species
mleu04217  Necroptosis
mleu04310  Wnt signaling pathway
mleu04380  Osteoclast differentiation
mleu04510  Focal adhesion
mleu04530  Tight junction
mleu04620  Toll-like receptor signaling pathway
mleu04621  NOD-like receptor signaling pathway
mleu04622  RIG-I-like receptor signaling pathway
mleu04625  C-type lectin receptor signaling pathway
mleu04657  IL-17 signaling pathway
mleu04658  Th1 and Th2 cell differentiation
mleu04659  Th17 cell differentiation
mleu04660  T cell receptor signaling pathway
mleu04664  Fc epsilon RI signaling pathway
mleu04668  TNF signaling pathway
mleu04722  Neurotrophin signaling pathway
mleu04723  Retrograde endocannabinoid signaling
mleu04728  Dopaminergic synapse
mleu04750  Inflammatory mediator regulation of TRP channels
mleu04910  Insulin signaling pathway
mleu04912  GnRH signaling pathway
mleu04914  Progesterone-mediated oocyte maturation
mleu04917  Prolactin signaling pathway
mleu04920  Adipocytokine signaling pathway
mleu04926  Relaxin signaling pathway
mleu04930  Type II diabetes mellitus
mleu04931  Insulin resistance
mleu04932  Non-alcoholic fatty liver disease
mleu04933  AGE-RAGE signaling pathway in diabetic complications
mleu04935  Growth hormone synthesis, secretion and action
mleu04936  Alcoholic liver disease
mleu05010  Alzheimer disease
mleu05012  Parkinson disease
mleu05016  Huntington disease
mleu05017  Spinocerebellar ataxia
mleu05020  Prion disease
mleu05022  Pathways of neurodegeneration - multiple diseases
mleu05132  Salmonella infection
mleu05133  Pertussis
mleu05135  Yersinia infection
mleu05142  Chagas disease
mleu05145  Toxoplasmosis
mleu05152  Tuberculosis
mleu05161  Hepatitis B
mleu05162  Measles
mleu05166  Human T-cell leukemia virus 1 infection
mleu05167  Kaposi sarcoma-associated herpesvirus infection
mleu05169  Epstein-Barr virus infection
mleu05170  Human immunodeficiency virus 1 infection
mleu05171  Coronavirus disease - COVID-19
mleu05200  Pathways in cancer
mleu05208  Chemical carcinogenesis - reactive oxygen species
mleu05210  Colorectal cancer
mleu05212  Pancreatic cancer
mleu05231  Choline metabolism in cancer
mleu05415  Diabetic cardiomyopathy
mleu05417  Lipid and atherosclerosis
mleu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    105554734 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105554734 (MAPK10)
   04012 ErbB signaling pathway
    105554734 (MAPK10)
   04014 Ras signaling pathway
    105554734 (MAPK10)
   04310 Wnt signaling pathway
    105554734 (MAPK10)
   04668 TNF signaling pathway
    105554734 (MAPK10)
   04068 FoxO signaling pathway
    105554734 (MAPK10)
   04071 Sphingolipid signaling pathway
    105554734 (MAPK10)
   04024 cAMP signaling pathway
    105554734 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105554734 (MAPK10)
   04137 Mitophagy - animal
    105554734 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    105554734 (MAPK10)
   04215 Apoptosis - multiple species
    105554734 (MAPK10)
   04217 Necroptosis
    105554734 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105554734 (MAPK10)
   04530 Tight junction
    105554734 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105554734 (MAPK10)
   04621 NOD-like receptor signaling pathway
    105554734 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    105554734 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    105554734 (MAPK10)
   04660 T cell receptor signaling pathway
    105554734 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    105554734 (MAPK10)
   04659 Th17 cell differentiation
    105554734 (MAPK10)
   04657 IL-17 signaling pathway
    105554734 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    105554734 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105554734 (MAPK10)
   04920 Adipocytokine signaling pathway
    105554734 (MAPK10)
   04912 GnRH signaling pathway
    105554734 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    105554734 (MAPK10)
   04917 Prolactin signaling pathway
    105554734 (MAPK10)
   04926 Relaxin signaling pathway
    105554734 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    105554734 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    105554734 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    105554734 (MAPK10)
   04722 Neurotrophin signaling pathway
    105554734 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105554734 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105554734 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105554734 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    105554734 (MAPK10)
   05231 Choline metabolism in cancer
    105554734 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105554734 (MAPK10)
   05212 Pancreatic cancer
    105554734 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105554734 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    105554734 (MAPK10)
   05161 Hepatitis B
    105554734 (MAPK10)
   05171 Coronavirus disease - COVID-19
    105554734 (MAPK10)
   05162 Measles
    105554734 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105554734 (MAPK10)
   05169 Epstein-Barr virus infection
    105554734 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105554734 (MAPK10)
   05135 Yersinia infection
    105554734 (MAPK10)
   05133 Pertussis
    105554734 (MAPK10)
   05152 Tuberculosis
    105554734 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105554734 (MAPK10)
   05142 Chagas disease
    105554734 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105554734 (MAPK10)
   05012 Parkinson disease
    105554734 (MAPK10)
   05016 Huntington disease
    105554734 (MAPK10)
   05017 Spinocerebellar ataxia
    105554734 (MAPK10)
   05020 Prion disease
    105554734 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    105554734 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105554734 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    105554734 (MAPK10)
   05415 Diabetic cardiomyopathy
    105554734 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105554734 (MAPK10)
   04936 Alcoholic liver disease
    105554734 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    105554734 (MAPK10)
   04931 Insulin resistance
    105554734 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105554734 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105554734 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mleu01001]
    105554734 (MAPK10)
Enzymes [BR:mleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     105554734 (MAPK10)
Protein kinases [BR:mleu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   105554734 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 105554734
NCBI-ProteinID: XP_011856692
Ensembl: ENSMLEG00000025936
LinkDB
Position
Unknown
AA seq 467 aa
MVFMSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDST
FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC
VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGI
KHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILG
MGYKENVDMWSVGCIMGEMIKGAVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRNY
VENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHP
YINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPS
GAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1404 nt   +upstreamnt  +downstreamnt
atggtatttatgagcctccatttcttatactactgcagtgaaccaactttggatgtgaaa
attgccttttgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattac
aacatgagcaaaagcaaagttgacaaccaattctacagcgtggaagtgggagactcaacc
ttcacagttctcaagcgctaccagaatctaaagcctattggctctggggctcagggcata
gtttgtgccgcgtatgatgctgtccttgacagaaatgtggccattaagaagctcagcaga
ccctttcagaaccaaacccatgccaagagagcgtaccgggagctggtcctcatgaagtgt
gtgaaccataaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggag
gagttccaagatgtttacttagtaatggaactgatggatgccaacttatgtcaagtgatt
cagatggaattagaccacgagcgaatgtcttacctgctgtaccaaatgctgtgtggcatt
aagcacctccactctgctggaattattcacagggatttaaaaccaagtaacattgtagtc
aagtctgattgcacattgaaaatcctggactttggactggccaggacagcaggcacaagc
ttcatgatgactccatatgtggtgacacgttattacagagccccggaggtcatcctgggg
atgggctacaaggagaacgttgacatgtggtcagtagggtgcatcatgggagaaatgata
aaaggtgcagtgctgtttcctggcactgatcatattgaccagtggaataaggtaattgaa
caactaggaacaccatgtccagaattcatgaagaaattgcaacccacagtaagaaactat
gtggagaatcggcccaagtatgcgggactcaccttccccaagctcttcccagattccctc
ttcccagcggactctgagcacaataaactcaaagccagccaagccagggacttgttgtca
aagatgctagtgattgacccagcaaaaagaatatcagtggacgacgccttacagcatccc
tacatcaacgtctggtatgacccagccgaagtggaggcgcctccacctcagatatatgac
aagcagttggatgaaagagaacacacaatcgaagaatggaaagaacttatctacaaggaa
gtaatgaactcagaagagaagactaaaaatggcgtagtaaaaggacagccttctccttca
ggtgcagcagtgaacagcagtgagagtctccctccatcctcgtctgtcaatgacatctcc
tccatgtccactgaccagaccctggcatctgacactgacagcagcctggaagcttcggca
ggacccctgggttgttgcaggtga

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