Mandrillus leucophaeus (drill): 105554734
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Entry
105554734 CDS
T08763
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu01522
Endocrine resistance
mleu04010
MAPK signaling pathway
mleu04012
ErbB signaling pathway
mleu04014
Ras signaling pathway
mleu04024
cAMP signaling pathway
mleu04068
FoxO signaling pathway
mleu04071
Sphingolipid signaling pathway
mleu04137
Mitophagy - animal
mleu04140
Autophagy - animal
mleu04141
Protein processing in endoplasmic reticulum
mleu04210
Apoptosis
mleu04215
Apoptosis - multiple species
mleu04217
Necroptosis
mleu04310
Wnt signaling pathway
mleu04380
Osteoclast differentiation
mleu04510
Focal adhesion
mleu04530
Tight junction
mleu04620
Toll-like receptor signaling pathway
mleu04621
NOD-like receptor signaling pathway
mleu04622
RIG-I-like receptor signaling pathway
mleu04625
C-type lectin receptor signaling pathway
mleu04657
IL-17 signaling pathway
mleu04658
Th1 and Th2 cell differentiation
mleu04659
Th17 cell differentiation
mleu04660
T cell receptor signaling pathway
mleu04664
Fc epsilon RI signaling pathway
mleu04668
TNF signaling pathway
mleu04722
Neurotrophin signaling pathway
mleu04723
Retrograde endocannabinoid signaling
mleu04728
Dopaminergic synapse
mleu04750
Inflammatory mediator regulation of TRP channels
mleu04910
Insulin signaling pathway
mleu04912
GnRH signaling pathway
mleu04914
Progesterone-mediated oocyte maturation
mleu04917
Prolactin signaling pathway
mleu04920
Adipocytokine signaling pathway
mleu04926
Relaxin signaling pathway
mleu04930
Type II diabetes mellitus
mleu04931
Insulin resistance
mleu04932
Non-alcoholic fatty liver disease
mleu04933
AGE-RAGE signaling pathway in diabetic complications
mleu04935
Growth hormone synthesis, secretion and action
mleu04936
Alcoholic liver disease
mleu05010
Alzheimer disease
mleu05012
Parkinson disease
mleu05016
Huntington disease
mleu05017
Spinocerebellar ataxia
mleu05020
Prion disease
mleu05022
Pathways of neurodegeneration - multiple diseases
mleu05132
Salmonella infection
mleu05133
Pertussis
mleu05135
Yersinia infection
mleu05142
Chagas disease
mleu05145
Toxoplasmosis
mleu05152
Tuberculosis
mleu05161
Hepatitis B
mleu05162
Measles
mleu05166
Human T-cell leukemia virus 1 infection
mleu05167
Kaposi sarcoma-associated herpesvirus infection
mleu05169
Epstein-Barr virus infection
mleu05170
Human immunodeficiency virus 1 infection
mleu05171
Coronavirus disease - COVID-19
mleu05200
Pathways in cancer
mleu05208
Chemical carcinogenesis - reactive oxygen species
mleu05210
Colorectal cancer
mleu05212
Pancreatic cancer
mleu05231
Choline metabolism in cancer
mleu05415
Diabetic cardiomyopathy
mleu05417
Lipid and atherosclerosis
mleu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
105554734 (MAPK10)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105554734 (MAPK10)
04012 ErbB signaling pathway
105554734 (MAPK10)
04014 Ras signaling pathway
105554734 (MAPK10)
04310 Wnt signaling pathway
105554734 (MAPK10)
04668 TNF signaling pathway
105554734 (MAPK10)
04068 FoxO signaling pathway
105554734 (MAPK10)
04071 Sphingolipid signaling pathway
105554734 (MAPK10)
04024 cAMP signaling pathway
105554734 (MAPK10)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105554734 (MAPK10)
04137 Mitophagy - animal
105554734 (MAPK10)
09143 Cell growth and death
04210 Apoptosis
105554734 (MAPK10)
04215 Apoptosis - multiple species
105554734 (MAPK10)
04217 Necroptosis
105554734 (MAPK10)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105554734 (MAPK10)
04530 Tight junction
105554734 (MAPK10)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
105554734 (MAPK10)
04621 NOD-like receptor signaling pathway
105554734 (MAPK10)
04622 RIG-I-like receptor signaling pathway
105554734 (MAPK10)
04625 C-type lectin receptor signaling pathway
105554734 (MAPK10)
04660 T cell receptor signaling pathway
105554734 (MAPK10)
04658 Th1 and Th2 cell differentiation
105554734 (MAPK10)
04659 Th17 cell differentiation
105554734 (MAPK10)
04657 IL-17 signaling pathway
105554734 (MAPK10)
04664 Fc epsilon RI signaling pathway
105554734 (MAPK10)
09152 Endocrine system
04910 Insulin signaling pathway
105554734 (MAPK10)
04920 Adipocytokine signaling pathway
105554734 (MAPK10)
04912 GnRH signaling pathway
105554734 (MAPK10)
04914 Progesterone-mediated oocyte maturation
105554734 (MAPK10)
04917 Prolactin signaling pathway
105554734 (MAPK10)
04926 Relaxin signaling pathway
105554734 (MAPK10)
04935 Growth hormone synthesis, secretion and action
105554734 (MAPK10)
09156 Nervous system
04728 Dopaminergic synapse
105554734 (MAPK10)
04723 Retrograde endocannabinoid signaling
105554734 (MAPK10)
04722 Neurotrophin signaling pathway
105554734 (MAPK10)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
105554734 (MAPK10)
09158 Development and regeneration
04380 Osteoclast differentiation
105554734 (MAPK10)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105554734 (MAPK10)
05208 Chemical carcinogenesis - reactive oxygen species
105554734 (MAPK10)
05231 Choline metabolism in cancer
105554734 (MAPK10)
09162 Cancer: specific types
05210 Colorectal cancer
105554734 (MAPK10)
05212 Pancreatic cancer
105554734 (MAPK10)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
105554734 (MAPK10)
05170 Human immunodeficiency virus 1 infection
105554734 (MAPK10)
05161 Hepatitis B
105554734 (MAPK10)
05171 Coronavirus disease - COVID-19
105554734 (MAPK10)
05162 Measles
105554734 (MAPK10)
05167 Kaposi sarcoma-associated herpesvirus infection
105554734 (MAPK10)
05169 Epstein-Barr virus infection
105554734 (MAPK10)
09171 Infectious disease: bacterial
05132 Salmonella infection
105554734 (MAPK10)
05135 Yersinia infection
105554734 (MAPK10)
05133 Pertussis
105554734 (MAPK10)
05152 Tuberculosis
105554734 (MAPK10)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105554734 (MAPK10)
05142 Chagas disease
105554734 (MAPK10)
09164 Neurodegenerative disease
05010 Alzheimer disease
105554734 (MAPK10)
05012 Parkinson disease
105554734 (MAPK10)
05016 Huntington disease
105554734 (MAPK10)
05017 Spinocerebellar ataxia
105554734 (MAPK10)
05020 Prion disease
105554734 (MAPK10)
05022 Pathways of neurodegeneration - multiple diseases
105554734 (MAPK10)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105554734 (MAPK10)
05418 Fluid shear stress and atherosclerosis
105554734 (MAPK10)
05415 Diabetic cardiomyopathy
105554734 (MAPK10)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
105554734 (MAPK10)
04936 Alcoholic liver disease
105554734 (MAPK10)
04932 Non-alcoholic fatty liver disease
105554734 (MAPK10)
04931 Insulin resistance
105554734 (MAPK10)
04933 AGE-RAGE signaling pathway in diabetic complications
105554734 (MAPK10)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
105554734 (MAPK10)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mleu01001
]
105554734 (MAPK10)
Enzymes [BR:
mleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
105554734 (MAPK10)
Protein kinases [BR:
mleu01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
105554734 (MAPK10)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
APH
FTA2
Motif
Other DBs
NCBI-GeneID:
105554734
NCBI-ProteinID:
XP_011856692
Ensembl:
ENSMLEG00000025936
LinkDB
All DBs
Position
Unknown
AA seq
467 aa
AA seq
DB search
MVFMSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDST
FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC
VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGI
KHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILG
MGYKENVDMWSVGCIMGEMIKGAVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRNY
VENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHP
YINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPS
GAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atggtatttatgagcctccatttcttatactactgcagtgaaccaactttggatgtgaaa
attgccttttgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattac
aacatgagcaaaagcaaagttgacaaccaattctacagcgtggaagtgggagactcaacc
ttcacagttctcaagcgctaccagaatctaaagcctattggctctggggctcagggcata
gtttgtgccgcgtatgatgctgtccttgacagaaatgtggccattaagaagctcagcaga
ccctttcagaaccaaacccatgccaagagagcgtaccgggagctggtcctcatgaagtgt
gtgaaccataaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggag
gagttccaagatgtttacttagtaatggaactgatggatgccaacttatgtcaagtgatt
cagatggaattagaccacgagcgaatgtcttacctgctgtaccaaatgctgtgtggcatt
aagcacctccactctgctggaattattcacagggatttaaaaccaagtaacattgtagtc
aagtctgattgcacattgaaaatcctggactttggactggccaggacagcaggcacaagc
ttcatgatgactccatatgtggtgacacgttattacagagccccggaggtcatcctgggg
atgggctacaaggagaacgttgacatgtggtcagtagggtgcatcatgggagaaatgata
aaaggtgcagtgctgtttcctggcactgatcatattgaccagtggaataaggtaattgaa
caactaggaacaccatgtccagaattcatgaagaaattgcaacccacagtaagaaactat
gtggagaatcggcccaagtatgcgggactcaccttccccaagctcttcccagattccctc
ttcccagcggactctgagcacaataaactcaaagccagccaagccagggacttgttgtca
aagatgctagtgattgacccagcaaaaagaatatcagtggacgacgccttacagcatccc
tacatcaacgtctggtatgacccagccgaagtggaggcgcctccacctcagatatatgac
aagcagttggatgaaagagaacacacaatcgaagaatggaaagaacttatctacaaggaa
gtaatgaactcagaagagaagactaaaaatggcgtagtaaaaggacagccttctccttca
ggtgcagcagtgaacagcagtgagagtctccctccatcctcgtctgtcaatgacatctcc
tccatgtccactgaccagaccctggcatctgacactgacagcagcctggaagcttcggca
ggacccctgggttgttgcaggtga
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