Myotis lucifugus (little brown bat): 102417755
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Entry
102417755 CDS
T07795
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf01521
EGFR tyrosine kinase inhibitor resistance
mlf01522
Endocrine resistance
mlf01524
Platinum drug resistance
mlf04010
MAPK signaling pathway
mlf04012
ErbB signaling pathway
mlf04014
Ras signaling pathway
mlf04015
Rap1 signaling pathway
mlf04022
cGMP-PKG signaling pathway
mlf04024
cAMP signaling pathway
mlf04062
Chemokine signaling pathway
mlf04066
HIF-1 signaling pathway
mlf04068
FoxO signaling pathway
mlf04071
Sphingolipid signaling pathway
mlf04072
Phospholipase D signaling pathway
mlf04114
Oocyte meiosis
mlf04140
Autophagy - animal
mlf04148
Efferocytosis
mlf04150
mTOR signaling pathway
mlf04151
PI3K-Akt signaling pathway
mlf04210
Apoptosis
mlf04218
Cellular senescence
mlf04261
Adrenergic signaling in cardiomyocytes
mlf04270
Vascular smooth muscle contraction
mlf04350
TGF-beta signaling pathway
mlf04360
Axon guidance
mlf04370
VEGF signaling pathway
mlf04371
Apelin signaling pathway
mlf04380
Osteoclast differentiation
mlf04510
Focal adhesion
mlf04520
Adherens junction
mlf04540
Gap junction
mlf04550
Signaling pathways regulating pluripotency of stem cells
mlf04611
Platelet activation
mlf04613
Neutrophil extracellular trap formation
mlf04620
Toll-like receptor signaling pathway
mlf04621
NOD-like receptor signaling pathway
mlf04625
C-type lectin receptor signaling pathway
mlf04650
Natural killer cell mediated cytotoxicity
mlf04657
IL-17 signaling pathway
mlf04658
Th1 and Th2 cell differentiation
mlf04659
Th17 cell differentiation
mlf04660
T cell receptor signaling pathway
mlf04662
B cell receptor signaling pathway
mlf04664
Fc epsilon RI signaling pathway
mlf04666
Fc gamma R-mediated phagocytosis
mlf04668
TNF signaling pathway
mlf04713
Circadian entrainment
mlf04720
Long-term potentiation
mlf04722
Neurotrophin signaling pathway
mlf04723
Retrograde endocannabinoid signaling
mlf04724
Glutamatergic synapse
mlf04725
Cholinergic synapse
mlf04726
Serotonergic synapse
mlf04730
Long-term depression
mlf04810
Regulation of actin cytoskeleton
mlf04910
Insulin signaling pathway
mlf04912
GnRH signaling pathway
mlf04914
Progesterone-mediated oocyte maturation
mlf04915
Estrogen signaling pathway
mlf04916
Melanogenesis
mlf04917
Prolactin signaling pathway
mlf04919
Thyroid hormone signaling pathway
mlf04921
Oxytocin signaling pathway
mlf04926
Relaxin signaling pathway
mlf04928
Parathyroid hormone synthesis, secretion and action
mlf04929
GnRH secretion
mlf04930
Type II diabetes mellitus
mlf04933
AGE-RAGE signaling pathway in diabetic complications
mlf04934
Cushing syndrome
mlf04935
Growth hormone synthesis, secretion and action
mlf04960
Aldosterone-regulated sodium reabsorption
mlf05010
Alzheimer disease
mlf05020
Prion disease
mlf05022
Pathways of neurodegeneration - multiple diseases
mlf05034
Alcoholism
mlf05132
Salmonella infection
mlf05133
Pertussis
mlf05135
Yersinia infection
mlf05140
Leishmaniasis
mlf05142
Chagas disease
mlf05145
Toxoplasmosis
mlf05152
Tuberculosis
mlf05160
Hepatitis C
mlf05161
Hepatitis B
mlf05163
Human cytomegalovirus infection
mlf05164
Influenza A
mlf05165
Human papillomavirus infection
mlf05166
Human T-cell leukemia virus 1 infection
mlf05167
Kaposi sarcoma-associated herpesvirus infection
mlf05170
Human immunodeficiency virus 1 infection
mlf05171
Coronavirus disease - COVID-19
mlf05200
Pathways in cancer
mlf05203
Viral carcinogenesis
mlf05205
Proteoglycans in cancer
mlf05206
MicroRNAs in cancer
mlf05207
Chemical carcinogenesis - receptor activation
mlf05208
Chemical carcinogenesis - reactive oxygen species
mlf05210
Colorectal cancer
mlf05211
Renal cell carcinoma
mlf05212
Pancreatic cancer
mlf05213
Endometrial cancer
mlf05214
Glioma
mlf05215
Prostate cancer
mlf05216
Thyroid cancer
mlf05218
Melanoma
mlf05219
Bladder cancer
mlf05220
Chronic myeloid leukemia
mlf05221
Acute myeloid leukemia
mlf05223
Non-small cell lung cancer
mlf05224
Breast cancer
mlf05225
Hepatocellular carcinoma
mlf05226
Gastric cancer
mlf05230
Central carbon metabolism in cancer
mlf05231
Choline metabolism in cancer
mlf05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mlf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102417755 (MAPK1)
04012 ErbB signaling pathway
102417755 (MAPK1)
04014 Ras signaling pathway
102417755 (MAPK1)
04015 Rap1 signaling pathway
102417755 (MAPK1)
04350 TGF-beta signaling pathway
102417755 (MAPK1)
04370 VEGF signaling pathway
102417755 (MAPK1)
04371 Apelin signaling pathway
102417755 (MAPK1)
04668 TNF signaling pathway
102417755 (MAPK1)
04066 HIF-1 signaling pathway
102417755 (MAPK1)
04068 FoxO signaling pathway
102417755 (MAPK1)
04072 Phospholipase D signaling pathway
102417755 (MAPK1)
04071 Sphingolipid signaling pathway
102417755 (MAPK1)
04024 cAMP signaling pathway
102417755 (MAPK1)
04022 cGMP-PKG signaling pathway
102417755 (MAPK1)
04151 PI3K-Akt signaling pathway
102417755 (MAPK1)
04150 mTOR signaling pathway
102417755 (MAPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102417755 (MAPK1)
04148 Efferocytosis
102417755 (MAPK1)
09143 Cell growth and death
04114 Oocyte meiosis
102417755 (MAPK1)
04210 Apoptosis
102417755 (MAPK1)
04218 Cellular senescence
102417755 (MAPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102417755 (MAPK1)
04520 Adherens junction
102417755 (MAPK1)
04540 Gap junction
102417755 (MAPK1)
04550 Signaling pathways regulating pluripotency of stem cells
102417755 (MAPK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102417755 (MAPK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102417755 (MAPK1)
04613 Neutrophil extracellular trap formation
102417755 (MAPK1)
04620 Toll-like receptor signaling pathway
102417755 (MAPK1)
04621 NOD-like receptor signaling pathway
102417755 (MAPK1)
04625 C-type lectin receptor signaling pathway
102417755 (MAPK1)
04650 Natural killer cell mediated cytotoxicity
102417755 (MAPK1)
04660 T cell receptor signaling pathway
102417755 (MAPK1)
04658 Th1 and Th2 cell differentiation
102417755 (MAPK1)
04659 Th17 cell differentiation
102417755 (MAPK1)
04657 IL-17 signaling pathway
102417755 (MAPK1)
04662 B cell receptor signaling pathway
102417755 (MAPK1)
04664 Fc epsilon RI signaling pathway
102417755 (MAPK1)
04666 Fc gamma R-mediated phagocytosis
102417755 (MAPK1)
04062 Chemokine signaling pathway
102417755 (MAPK1)
09152 Endocrine system
04910 Insulin signaling pathway
102417755 (MAPK1)
04929 GnRH secretion
102417755 (MAPK1)
04912 GnRH signaling pathway
102417755 (MAPK1)
04915 Estrogen signaling pathway
102417755 (MAPK1)
04914 Progesterone-mediated oocyte maturation
102417755 (MAPK1)
04917 Prolactin signaling pathway
102417755 (MAPK1)
04921 Oxytocin signaling pathway
102417755 (MAPK1)
04926 Relaxin signaling pathway
102417755 (MAPK1)
04935 Growth hormone synthesis, secretion and action
102417755 (MAPK1)
04919 Thyroid hormone signaling pathway
102417755 (MAPK1)
04928 Parathyroid hormone synthesis, secretion and action
102417755 (MAPK1)
04916 Melanogenesis
102417755 (MAPK1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
102417755 (MAPK1)
04270 Vascular smooth muscle contraction
102417755 (MAPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
102417755 (MAPK1)
09156 Nervous system
04724 Glutamatergic synapse
102417755 (MAPK1)
04725 Cholinergic synapse
102417755 (MAPK1)
04726 Serotonergic synapse
102417755 (MAPK1)
04720 Long-term potentiation
102417755 (MAPK1)
04730 Long-term depression
102417755 (MAPK1)
04723 Retrograde endocannabinoid signaling
102417755 (MAPK1)
04722 Neurotrophin signaling pathway
102417755 (MAPK1)
09158 Development and regeneration
04360 Axon guidance
102417755 (MAPK1)
04380 Osteoclast differentiation
102417755 (MAPK1)
09159 Environmental adaptation
04713 Circadian entrainment
102417755 (MAPK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102417755 (MAPK1)
05206 MicroRNAs in cancer
102417755 (MAPK1)
05205 Proteoglycans in cancer
102417755 (MAPK1)
05207 Chemical carcinogenesis - receptor activation
102417755 (MAPK1)
05208 Chemical carcinogenesis - reactive oxygen species
102417755 (MAPK1)
05203 Viral carcinogenesis
102417755 (MAPK1)
05230 Central carbon metabolism in cancer
102417755 (MAPK1)
05231 Choline metabolism in cancer
102417755 (MAPK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102417755 (MAPK1)
09162 Cancer: specific types
05210 Colorectal cancer
102417755 (MAPK1)
05212 Pancreatic cancer
102417755 (MAPK1)
05225 Hepatocellular carcinoma
102417755 (MAPK1)
05226 Gastric cancer
102417755 (MAPK1)
05214 Glioma
102417755 (MAPK1)
05216 Thyroid cancer
102417755 (MAPK1)
05221 Acute myeloid leukemia
102417755 (MAPK1)
05220 Chronic myeloid leukemia
102417755 (MAPK1)
05218 Melanoma
102417755 (MAPK1)
05211 Renal cell carcinoma
102417755 (MAPK1)
05219 Bladder cancer
102417755 (MAPK1)
05215 Prostate cancer
102417755 (MAPK1)
05213 Endometrial cancer
102417755 (MAPK1)
05224 Breast cancer
102417755 (MAPK1)
05223 Non-small cell lung cancer
102417755 (MAPK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102417755 (MAPK1)
05170 Human immunodeficiency virus 1 infection
102417755 (MAPK1)
05161 Hepatitis B
102417755 (MAPK1)
05160 Hepatitis C
102417755 (MAPK1)
05171 Coronavirus disease - COVID-19
102417755 (MAPK1)
05164 Influenza A
102417755 (MAPK1)
05163 Human cytomegalovirus infection
102417755 (MAPK1)
05167 Kaposi sarcoma-associated herpesvirus infection
102417755 (MAPK1)
05165 Human papillomavirus infection
102417755 (MAPK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
102417755 (MAPK1)
05135 Yersinia infection
102417755 (MAPK1)
05133 Pertussis
102417755 (MAPK1)
05152 Tuberculosis
102417755 (MAPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102417755 (MAPK1)
05140 Leishmaniasis
102417755 (MAPK1)
05142 Chagas disease
102417755 (MAPK1)
09164 Neurodegenerative disease
05010 Alzheimer disease
102417755 (MAPK1)
05020 Prion disease
102417755 (MAPK1)
05022 Pathways of neurodegeneration - multiple diseases
102417755 (MAPK1)
09165 Substance dependence
05034 Alcoholism
102417755 (MAPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102417755 (MAPK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102417755 (MAPK1)
04933 AGE-RAGE signaling pathway in diabetic complications
102417755 (MAPK1)
04934 Cushing syndrome
102417755 (MAPK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102417755 (MAPK1)
01524 Platinum drug resistance
102417755 (MAPK1)
01522 Endocrine resistance
102417755 (MAPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlf01001
]
102417755 (MAPK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mlf03036
]
102417755 (MAPK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mlf04147
]
102417755 (MAPK1)
Enzymes [BR:
mlf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
102417755 (MAPK1)
Protein kinases [BR:
mlf01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
102417755 (MAPK1)
Chromosome and associated proteins [BR:
mlf03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
102417755 (MAPK1)
Exosome [BR:
mlf04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
102417755 (MAPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
STATB_N
Haspin_kinase
FTA2
Kdo
Kinase-like
Motif
Other DBs
NCBI-GeneID:
102417755
NCBI-ProteinID:
XP_014320494
Ensembl:
ENSMLUG00000005952
LinkDB
All DBs
Position
Unknown
AA seq
324 aa
AA seq
DB search
MIKNSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIE
QMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLL
LNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGC
ILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWN
RLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELD
DLPKEKLKELIFEETARFQPGYRS
NT seq
975 nt
NT seq
+upstream
nt +downstream
nt
atgatcaaaaactctgcttatgataatgtcaacaaagttcgagtagctatcaagaaaatc
agtccttttgagcaccagacctactgccagagaaccctgagggagataaaaatcctactg
cgcttcagacacgagaacatcattggaatcaatgatattattcgagcgccaaccatcgag
caaatgaaagatgtatatatagtacaggacctcatggaaacagatctctacaagctcttg
aagacacaacacctcagcaacgaccatatctgctattttctttaccagatcctcagaggg
ttaaaatatatccattcagctaatgtactgcaccgtgacctcaaaccttccaacctgttg
ctcaacaccacctgtgatctcaagatctgtgattttggcttggcccgcgttgcagatcca
gaccatgatcacacagggttcctgacagagtatgtagccacacgttggtacagggctcca
gaaattatgttgaattccaagggctataccaagtccattgatatttggtctgtaggctgc
attctggcagagatgctctccaacaggcccatcttcccagggaagcattaccttgaccag
ctgaaccacattctgggtattcttggatccccatcacaggaagacctgaactgcataatc
aacctaaaagctagaaactatttgctttctctcccacacaaaaataaggtgccatggaac
aggctgttcccaaatgctgattccaaagctctggatttactggacaaaatgttgaccttc
aaccctcacaagaggattgaagtagaacaggcgctagcccacccgtatctggagcagtat
tatgacccaagtgatgagcccattgctgaagcaccattcaagtttgacatggaattggat
gacttgcctaaggagaagctcaaagaactcatttttgaagagaccgctagattccagcct
ggatatagatcttaa
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