Myotis lucifugus (little brown bat): 102418922
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Entry
102418922 CDS
T07795
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf00790
Folate biosynthesis
mlf01100
Metabolic pathways
mlf01240
Biosynthesis of cofactors
mlf01523
Antifolate resistance
mlf04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
102418922 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102418922 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102418922 (FPGS)
Enzymes [BR:
mlf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
102418922 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
102418922
NCBI-ProteinID:
XP_014322952
Ensembl:
ENSMLUG00000013491
LinkDB
All DBs
Position
Unknown
AA seq
592 aa
AA seq
DB search
MSRARSHRRASLFLAAVFPRGVTTRVTGRRELSARPAPQEPGMEYQDAVRTLNSLQTNAS
YLEEVKRRRGDLQTQLETMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFRSPGSSPHLVQVRERIRINGQPISPEHFTKHFWRLYHRLEETKDSSSCVSMP
AYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDT
MEKIAWQKGGIFKHGVPAFTVPQPDGPLAVLRERAEQISCPLYLCPPLEALEEGGPPLTL
GLEGEHQRSNAALALQLARCWLQRKDHQGIGELKASRPSLLCQLPLAPVFQPTSHMRHGL
RDTEWLGRTQILCRGPLTWYLDGAHTCSSVQACVRWFRQALHRRKSGPEVPEVRVLLFNS
TGDRDPAPLLKLLRPCQFDYAVFCPNLTEVASTGNADQQNFMVTLDQVLLRCLEHQQHWS
RLDEEAASPDLWSTPSPEAGGPAALLLAPRLPHTHGTSSLVFSCISHALQWISQGRDPDF
QTPSSPRDLLAHPVANSGASVLREAAAIHVLVTGSLHLVGGVLKLLDPSLSQ
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcgtagccaccggcgcgcgagtctcttcctggcagcggttttcccgcgc
ggggtaacgaccagggtcacgggcaggcgggagctgagcgcgcggcccgcgccgcaggag
ccgggcatggaataccaggatgctgtgcgcacactcaacagcctgcagaccaatgccagc
tacctggaggaggtgaagcgccggcggggtgacctccagacacagctggaaaccatgaag
ctgtacttggcacggagtgggctgcaggtggaggacttggaccagctgaacatcatccac
gttactgggacgaaggggaagggctccacctgtgccttcactgaacggatcctccggaac
tatggcctgaagacgggattctttagatctcccggcagctctccccacctggtgcaggtg
cgcgagcggatccgcatcaatgggcagcccatcagccccgagcacttcaccaagcacttc
tggcgcctctaccatcggctggaggagaccaaggacagcagcagctgtgtctccatgcct
gcatacttccgcttcctcacgctcatggccttccatgtcttcctgcaagagaaggtggac
ctggcagtggtggaagtgggtatcggtggggcttatgactgcaccaacataatcaggaag
cctgtggtatgtggggtctcctctcttggcatcgaccacactagccttctgggggacacg
atggagaagatcgcctggcagaaagggggcatcttcaagcatggcgtccctgccttcacc
gtgccccagcctgatgggcccctggccgtgctgagggagcgtgctgagcagatctcatgt
cccctctacctgtgtccaccgctggaagccctggaggaaggggggccaccgttgaccctg
ggcctggagggagagcaccagcggtccaatgccgcgttggccttgcagctggcccgctgc
tggctgcagcgaaaggaccaccaaggcattggggagctgaaagcgtccaggcccagcctc
ctgtgtcagctgcctctggcacccgtgttccagcccacatcccacatgcggcatgggctt
cgggacacggagtggcttggccggacgcagatactgtgccgcgggcccctcacctggtac
ctggatggcgcacacacctgcagcagcgtgcaggcctgtgtgcgctggttccgccaggcg
ctgcaccgccgcaagagtggacctgaggtgcctgaggtgcgcgtcctgctcttcaactcc
acgggtgaccgggacccggcgcccctgctgaagctgttgcggccctgccagtttgactat
gctgttttctgccctaacttgacggaggtggcatccacgggcaacgcagaccagcagaac
ttcatggtgaccctggaccaggtgttgctccgctgcttggaacaccagcagcactggagc
cgcctggatgaggaggcggccagcccggacctctggagcacccccagccccgaggctggt
gggccggcggccctgctgctggcaccccgcctgccccacacccacggcaccagctccctc
gtcttcagctgcatctcccatgctttgcagtggatcagccagggccgggaccctgacttc
cagacacccagttccccacgggaccttctcgcccaccctgtggcaaacagcggggccagc
gtgctccgagaggctgctgccatccacgtgctggtcacgggaagcctgcacctggtgggc
ggcgtcctgaagctgctggatccctccctgtcccagtag
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