Myotis lucifugus (little brown bat): 102420000
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Entry
102420000 CDS
T07795
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf00562
Inositol phosphate metabolism
mlf01100
Metabolic pathways
mlf01521
EGFR tyrosine kinase inhibitor resistance
mlf04012
ErbB signaling pathway
mlf04014
Ras signaling pathway
mlf04020
Calcium signaling pathway
mlf04062
Chemokine signaling pathway
mlf04064
NF-kappa B signaling pathway
mlf04066
HIF-1 signaling pathway
mlf04070
Phosphatidylinositol signaling system
mlf04072
Phospholipase D signaling pathway
mlf04360
Axon guidance
mlf04370
VEGF signaling pathway
mlf04380
Osteoclast differentiation
mlf04517
IgSF CAM signaling
mlf04611
Platelet activation
mlf04613
Neutrophil extracellular trap formation
mlf04625
C-type lectin receptor signaling pathway
mlf04650
Natural killer cell mediated cytotoxicity
mlf04662
B cell receptor signaling pathway
mlf04664
Fc epsilon RI signaling pathway
mlf04666
Fc gamma R-mediated phagocytosis
mlf04670
Leukocyte transendothelial migration
mlf04722
Neurotrophin signaling pathway
mlf04750
Inflammatory mediator regulation of TRP channels
mlf04919
Thyroid hormone signaling pathway
mlf04933
AGE-RAGE signaling pathway in diabetic complications
mlf04935
Growth hormone synthesis, secretion and action
mlf05167
Kaposi sarcoma-associated herpesvirus infection
mlf05169
Epstein-Barr virus infection
mlf05170
Human immunodeficiency virus 1 infection
mlf05171
Coronavirus disease - COVID-19
mlf05200
Pathways in cancer
mlf05205
Proteoglycans in cancer
mlf05206
MicroRNAs in cancer
mlf05214
Glioma
mlf05223
Non-small cell lung cancer
mlf05225
Hepatocellular carcinoma
Module
mlf_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
102420000 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
102420000 (PLCG2)
04014 Ras signaling pathway
102420000 (PLCG2)
04370 VEGF signaling pathway
102420000 (PLCG2)
04064 NF-kappa B signaling pathway
102420000 (PLCG2)
04066 HIF-1 signaling pathway
102420000 (PLCG2)
04020 Calcium signaling pathway
102420000 (PLCG2)
04070 Phosphatidylinositol signaling system
102420000 (PLCG2)
04072 Phospholipase D signaling pathway
102420000 (PLCG2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
102420000 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102420000 (PLCG2)
04613 Neutrophil extracellular trap formation
102420000 (PLCG2)
04625 C-type lectin receptor signaling pathway
102420000 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
102420000 (PLCG2)
04662 B cell receptor signaling pathway
102420000 (PLCG2)
04664 Fc epsilon RI signaling pathway
102420000 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
102420000 (PLCG2)
04670 Leukocyte transendothelial migration
102420000 (PLCG2)
04062 Chemokine signaling pathway
102420000 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
102420000 (PLCG2)
04919 Thyroid hormone signaling pathway
102420000 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
102420000 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
102420000 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
102420000 (PLCG2)
04380 Osteoclast differentiation
102420000 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102420000 (PLCG2)
05206 MicroRNAs in cancer
102420000 (PLCG2)
05205 Proteoglycans in cancer
102420000 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102420000 (PLCG2)
05214 Glioma
102420000 (PLCG2)
05223 Non-small cell lung cancer
102420000 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
102420000 (PLCG2)
05171 Coronavirus disease - COVID-19
102420000 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
102420000 (PLCG2)
05169 Epstein-Barr virus infection
102420000 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102420000 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102420000 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlf04131
]
102420000 (PLCG2)
Enzymes [BR:
mlf01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
102420000 (PLCG2)
Membrane trafficking [BR:
mlf04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
102420000 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
102420000 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF_HAND_2_PLCG
C2
SH3_1
SH3_9
PH
EF_HAND_1_PLCG
PH_12
SH2_1
SH3_2
PH_14
Adhesin_E
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
102420000
NCBI-ProteinID:
XP_006087103
Ensembl:
ENSMLUG00000014908
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MTTMVNVDALPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKSSKDFERAKTVRQKEDCCFTILYGTQFVLSTLSLATDSKEDAT
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKAILPLVNFKVSSA
KFLKDKFAEIGANKDEFSFEQFHLLYKKLMFEQQKSILDEFKKDSSVFILGSTDRPDASA
VHLHDFQRFLLHEQQELWAQDVNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRYMARV
FKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDPIDLKWTRHYCAIADAKLSFSDDIEQTVEEEVPQDTPPTELHFGEKWFHKKVEKR
TSAEKLLQEYCSETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTMKYY
LTDNLMFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMKLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKQSDELSFCRGALIHNVSKEPGGWWKGDYGTKIQHYFPSNYVEDISTVDVEELEKQII
EDNPLGSLCKGILDLNTYNVVKAPHGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIRQITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSVVRQKPIELLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTGDKY
MQMNQALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWASTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVNEFNVNENQLHLYQEKCNRRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccatggtcaacgtggacgccctcccggaatatgagaagagtcagatcaagaga
gccctggagctgggcaccgtgatgaccgtgttcagcttccgcaagtccaccccggagcgc
aggaccgtccaggtgatcatggagacgcggcaggtggcctggagtaagacggccgacaag
atcgagggcttcttggatatcatggaaatcaaggaaatccgcccagggaagagctccaag
gacttcgagcgtgcaaagacagtccgccagaaggaagactgctgcttcaccatcttgtat
ggcacccagttcgtcctcagcacactcagcttagcaacggactcgaaggaagatgcaacc
aagtggctctctggcttgaaaatcttacaccaggaagcgatgagcgcgtccacacccacc
atcattgagagttggctgagaaagcagatttattcggtggatcaaaccagaagaaacagc
atcagcctccgagagttgaaggccatcttgcccctggtcaacttcaaagtgagcagtgcc
aagttcctcaaggataagtttgcggaaataggcgcaaacaaagatgaattcagctttgaa
cagttccatctcctctataaaaaacttatgtttgaacagcaaaaatcgattcttgacgaa
ttcaaaaaagattcctccgtgttcatcctgggcagtactgaccggccggatgcctccgcg
gttcacctgcatgacttccagcggtttctcttacatgaacagcaggaactttgggctcag
gatgtgaacaaagtccgtgagaggatgacaaagtttatcgacgacacgatgagggaaacc
gcggagcccttcttgtttgttgatgagttcctcacgtacctgttttcacgggagaacagc
atttgggatgagaagtatgacgtggtggacatgcaggacatgaacaaccccttgtctcat
tactggatctcctcgtcacataacacgtacctcacaggtgaccagctgcggagtgagtcg
tccccggaggcgtatatccgctgtctgcgcatgggctgtcgctgcattgagttggactgc
tgggacgggcccgatgggaagcccatcatctaccacggctggacccggaccaccaagatc
aagtttgatgacgttgtgcaggccatcaaagaccacgcctttgtcacctcaagcttcccc
gtgatcctgtccatcgaggagcactgttgcgtggagcagcagcgctacatggccagagtg
ttcaaggaggtgtttggcgacctgctgctgacgaagcccacggaggccagtgctgaccag
ctgccctcgcccagccagctgcgggagaagatcatcatcaagcacaagaagctgggcccc
cgaggcgacgtggatgtcaacatggaggacaagaaagatgagcacaagcagcagggggag
ctgtacatgtgggaccccatcgacctgaaatggactcggcactactgcgccattgccgat
gccaagctgtccttcagcgacgacattgagcagactgtggaagaggaagtgccccaggac
acgccccccacagagctgcattttggagagaagtggttccacaagaaggtggagaagagg
acaagtgctgagaagctgttgcaggaatactgctcagagacggggggcaaggacggcacc
ttcctggtgcgggagagcgagacattccccaacgactacaccctgtccttctggcggtcc
ggccgggtccagcactgccggatccgctccaccatggagggcgggaccatgaagtactac
ctgactgacaacctcatgttcaccagcatctacgccctcatccagcactaccgcgagacg
cacctgcgctgcgccgagttcgagctccgactcaccgaccccgtgcccaaccccaacccc
catgaatcaaagccgtggtactatgacgggctgagccgtggagaagcggaggacatgctg
atgagggttccccgggacggcgccttcctcatccggaagcgggaaggtagcgactcctac
gccatcaccttcagggcccggggcaaggtgaaacactgccgcatcaaccgggacggccgg
cacttcgtgctggggacctccgcctacttcgagagcctggtggagcttgtcagctactac
gagaagcacgcgctctaccggaagatgaagctgcgctaccccgtgacgcccgagctcctg
gagcgctacaacatggaaagagatataaactccctgtatgacgtcagcagaatgtatgtg
gatcccagtgaaatcaatccttccatgcctcagagaaccgtgaaagctctgtatgactac
aaagccaagcagagtgatgagctgagcttctgccgcggcgccctcattcacaacgtctcc
aaggagcccggaggctggtggaaaggagactacggaaccaaaatccagcactacttcccg
tccaattatgtcgaggacatttcaacggttgatgtggaggagctcgagaagcagattatt
gaagacaatcccttagggtctctttgcaaaggaatattggatctcaacacctataatgtt
gtgaaagccccgcacgggaaaaaccagaagcccttcgtcttcatcctggagcccaagaag
cagggtgacccgccggtggagttcgccacggaccgggtggaggagctcttcgagtggttc
cagagcatccggcagatcacctggaagatcgacaccaaggagaacaacatgaaatactgg
gagaagaaccagtcgatcgccatcgagctctcggacctggtcgtctactgcaaaccaacc
agcaagaccaaagacaatttagagaatcccgacttccgagagatccgttcctttgtggag
acgaaggccgacagcgtcgtcagacagaaacccattgagctcctgaagtacaatcagaag
ggcctgacccgtgtttacccgaagggacagagggtggactcctccaactacgaccccttc
cgcctctggctgtgcggctcccaaatggtggcactcaacttccagactggagacaaatac
atgcagatgaaccaggccttgttttcactcaacgggaggaccggctacgtcctgcaaccc
gagagcatgaggacggagaagtatgaccccatgccgcccgagtcccagaggaagattctg
atgaccttgacggtcaaggttctcggggctcgccatctccccaagctcggacgaagtatt
gcatgtccctttgtggaggtggaaatatgtggagccgaatatgacaacaacaagtttaag
acgacggttgtgaatgacaatggcctaagccctgtttgggcttcaacgcaggagaaggtg
acatttgaaatctatgacccaaacctggcatttctgcgctttgtggtgtacgaggaagat
atgttcagcgaccccaactttctcgcgcatgctacttaccccattaaaggaatcaagtca
ggatttagatctgttcctctgaagaacgggtacagtgaagacatcgagctggcttccctc
ctggttttctgcgagatgcggccagtgctggagagtgaagaggaactgtactcttcctgt
cgccagctgcggaggcggcaagaagagctgaacaaccagctcttcctatatgacacacac
cagaacttgcgcaatgccaaccgggatgccctcgttaatgagttcaatgtcaatgagaac
cagctccatctgtaccaggagaagtgcaaccggaggttaagagagaagagagtcagcaac
agcaagttttactcatag
DBGET
integrated database retrieval system
