Myotis lucifugus (little brown bat): 102420466
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Entry
102420466 CDS
T07795
Symbol
JAK2
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf01521
EGFR tyrosine kinase inhibitor resistance
mlf04062
Chemokine signaling pathway
mlf04081
Hormone signaling
mlf04148
Efferocytosis
mlf04151
PI3K-Akt signaling pathway
mlf04217
Necroptosis
mlf04550
Signaling pathways regulating pluripotency of stem cells
mlf04630
JAK-STAT signaling pathway
mlf04658
Th1 and Th2 cell differentiation
mlf04659
Th17 cell differentiation
mlf04725
Cholinergic synapse
mlf04917
Prolactin signaling pathway
mlf04920
Adipocytokine signaling pathway
mlf04933
AGE-RAGE signaling pathway in diabetic complications
mlf04935
Growth hormone synthesis, secretion and action
mlf05140
Leishmaniasis
mlf05145
Toxoplasmosis
mlf05152
Tuberculosis
mlf05161
Hepatitis B
mlf05164
Influenza A
mlf05167
Kaposi sarcoma-associated herpesvirus infection
mlf05168
Herpes simplex virus 1 infection
mlf05200
Pathways in cancer
mlf05207
Chemical carcinogenesis - receptor activation
mlf05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mlf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102420466 (JAK2)
04151 PI3K-Akt signaling pathway
102420466 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
102420466 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102420466 (JAK2)
09143 Cell growth and death
04217 Necroptosis
102420466 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102420466 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
102420466 (JAK2)
04659 Th17 cell differentiation
102420466 (JAK2)
04062 Chemokine signaling pathway
102420466 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
102420466 (JAK2)
04917 Prolactin signaling pathway
102420466 (JAK2)
04935 Growth hormone synthesis, secretion and action
102420466 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
102420466 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102420466 (JAK2)
05207 Chemical carcinogenesis - receptor activation
102420466 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102420466 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
102420466 (JAK2)
05164 Influenza A
102420466 (JAK2)
05168 Herpes simplex virus 1 infection
102420466 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
102420466 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
102420466 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102420466 (JAK2)
05140 Leishmaniasis
102420466 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102420466 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102420466 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102420466 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlf01001
]
102420466 (JAK2)
Enzymes [BR:
mlf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102420466 (JAK2)
Protein kinases [BR:
mlf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102420466 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
Kdo
ABC1
RIO1
Kinase-like
FERM_C_FAK1
FERM_M
Motif
Other DBs
NCBI-GeneID:
102420466
NCBI-ProteinID:
XP_014315881
Ensembl:
ENSMLUG00000012756
LinkDB
All DBs
Position
Unknown
AA seq
1128 aa
AA seq
DB search
MEMACLTMTEMEGTCTPPMHQNGDIPGITDSVKQIDPVLQVYLYHSPGKTEGDYLKFSTG
EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNYVFHIDESTRHNVLYRIRFYF
PYWYCSGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKENDQTPLDVYSSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVSIKQASQEGSNESRXVTIHKQMEIELSSLKEALS
FVSLIDGYYRLTADAHHYLCKEVASPVVLENIQSNCHGPISMDFAISKLKKAGNQTGLYV
LRCSPKEFNKYFLTFAVEHDNVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNCYQME
TVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNSVSDVPTSPTLQRHNNVNQMVFHKIRNED
LVFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSQL
SHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMHFL
EEKNLIHGNVCAKNILLIREEDRKSGNPPFIKLSDPGISVTVLPKDILQERIPWVPPECI
ENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELANLI
NNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQF
EERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKS
LQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICKGM
EYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPE
SLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKN
NGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRNLALRVDQIRDNIAG
NT seq
3387 nt
NT seq
+upstream
nt +downstream
nt
atggaaatggcttgcctcacaatgacagaaatggaaggaacatgcacacctcctatgcat
cagaatggagatattcctggaattactgattctgtgaagcaaatagatccagtccttcag
gtgtatctttatcattcccctgggaaaactgagggagattacctgaagttttcaactggg
gaatatgttgcagaagaaatttgtgttgctgcttctaaagcctgtggaatcacacctgtg
tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccgcccaactat
gtcttccatatagatgagtcaaccaggcacaatgtactctacagaataagattttacttt
ccttactggtattgtagcggcagcaacagaacttatcggcatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgttatgtcttacctttttgctcagtggcggcatgat
tttttgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaatgatcaaaccccactcgacgtc
tatagctctatcagctataagacattcttaccaaaatgtattcgagcaaagatccaagac
tatcatattttgacaagaaagcgaataaggtaccgatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgaaacactgacagaacaggatttacagttatattgtgacttt
cccgatattattgatgtcagtattaagcaggcaagccaagaaggctcaaatgaaagcaga
nttgtaactatccataaacagatggaaattgaacttagttcattaaaggaggctttgtct
tttgtgtcattaattgatggatattatagattaactgcagatgcacatcattacctctgt
aaagaagtagcatctccagtggtgcttgaaaatatacaaagcaattgtcatggcccaatt
tcaatggattttgccataagtaaactgaagaaagcaggtaatcagactggactttatgta
cttcgatgcagtcctaaggagtttaataaatattttttgacttttgctgtcgagcatgat
aatgtcattgaatataagcactgtctgattacaaaaaatgagaatggagaatacaacctc
agtgggactaagaagaacttcagtaatcttaaagatcttttgaattgctaccagatggaa
actgttcgctcagacaatataattttccagtttacaaaatgctgtcctccaaagccaaaa
gataaatcaaaccttctagtctttagaacaaatagtgtttctgatgtaccaacctcacca
acattacagagacataataatgtgaaccaaatggtgtttcacaaaatcagaaatgaagat
ttagtatttaatgaaagtcttggccaaggcacttttacaaaaatttttaaaggtgtaaga
agagaagtaggagattatggtcaactgcatgaaacagaagttcttttaaaagttctggat
aaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagccagctt
tctcacaagcatctggttttaaattatggagtatgtgtctgtggagaggagaatattctg
gttcaggagtttgtgaaatttggatcactagatacatatttgaaaaagaataaaaattct
ataaatatattatggaaacttgaagtggctaaacagttggcatgggccatgcattttcta
gaagaaaaaaaccttattcatgggaatgtgtgtgccaaaaacattctacttatcagagaa
gaagacaggaagtcaggaaatcctcctttcatcaaacttagtgatcctggcattagtgtt
acagttttaccaaaggacattcttcaggagagaataccatgggtaccacctgaatgtatt
gaaaatcctaaaaacttaaacttggcaacagacaaatggagttttggtaccactttgtgg
gaaatctgcagtggaggagataagcctctgagtgctttggattctcaaagaaagctacag
ttttatgaagatagacaccagcttcctgcaccaaagtggacagaattagcaaatcttatt
aataattgtatggattatgaaccagattttagaccttctttcagagccatcatacgagat
cttaatagtttgtttactccagattatgaattgttaacagagaatgacatgttaccaaat
atgaggataggtgccctagggttttctggagcttttgaagaccgagaccctactcagttt
gaagagagacacttgaaatttctgcagcaacttggcaagggtaactttgggagtgttgag
atgtgccggtatgaccctctacaagacaacactggggaggtggtggccgtgaaaaagctc
cagcacagtactgaagagcacctcagagactttgaaagggaaattgaaatccttaaatcc
ctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggccgacgtaat
ctaagattaattatggaatatttaccatatggaagtttacgagactatctccaaaagcat
aaagaacgaatagatcataagaaacttctgcaatatacatctcaaatatgcaagggtatg
gaatatcttggtacaaaaaggtatatccacagggatctggcaacaaggaatatattggta
gagaatgaaaacagagttaaaattggagattttgggttaaccaaagtcttgccacaagac
aaagaatactacaaagtgaaagaacctggtgaaagtcctatattctggtatgctccagaa
tcactgacagagagcaagttttctgtggcctcagatgtttggagctttggagtggttcta
tatgaacttttcacctatattgagaagagtaaaagtccaccagcggaattcatgcgtatg
attggcaatgacaaacaaggacagatgattgtgtttcatttgatagaactcttgaagaat
aatggaagattaccaagaccagatggatgcccagatgagatctatctgatcatgacagaa
tgctggaataataatgtaaatcaacgtccatctttcagaaacctagctcttcgagttgat
caaataagggacaacatagctggatga
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integrated database retrieval system
