Entry
Symbol
MGST2
Name
(RefSeq) microsomal glutathione S-transferase 2 isoform X1
KO
Organism
mlf Myotis lucifugus (little brown bat)
Pathway
mlf00980 Metabolism of xenobiotics by cytochrome P450
mlf00982 Drug metabolism - cytochrome P450
mlf00983 Drug metabolism - other enzymes
mlf05204 Chemical carcinogenesis - DNA adducts
mlf05207 Chemical carcinogenesis - receptor activation
mlf05208 Chemical carcinogenesis - reactive oxygen species
mlf05418 Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlf00001 ]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102421114 (MGST2)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
102421114 (MGST2)
00982 Drug metabolism - cytochrome P450
102421114 (MGST2)
00983 Drug metabolism - other enzymes
102421114 (MGST2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102421114 (MGST2)
05204 Chemical carcinogenesis - DNA adducts
102421114 (MGST2)
05207 Chemical carcinogenesis - receptor activation
102421114 (MGST2)
05208 Chemical carcinogenesis - reactive oxygen species
102421114 (MGST2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102421114 (MGST2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
102421114 (MGST2)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102421114 (MGST2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:mlf02000 ]
102421114 (MGST2)
Enzymes [BR:mlf01000 ]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.18 glutathione transferase
102421114 (MGST2)
Transporters [BR:mlf02000 ]
Other transporters
Pores ion channels [TC:1 ]
102421114 (MGST2)
BRITE hierarchy
SSDB
Ortholog Paralog GFIT
Motif
Motif
Other DBs
LinkDB
All DBs
Position
Unknown
AA seq
146 aa AA seq DB search
MAGNSVLLAAVSVLSACQQSYFAMHVAKARLKYKVMPPAVSGSPEFERIFRAQQNGVEFY
PLFMITLWMAGWYFNQGFATCLGLVYMYARHQYFWGYSEAAKKRILGFRLSLGALALLAV
LAVLGIANSFLDEYLDIDIAKKLRHF
NT seq
441 nt NT seq +upstream nt +downstream nt
atggccgggaactcagttttgctggctgctgtctctgtcctctctgcctgtcagcaaagt
tattttgctatgcatgtagcaaaagcaagattaaaatacaaagttatgcccccagcagtc
tctgggtcacctgagtttgagagaatatttcgtgcacaacaaaatggtgtggagttttac
ccgctgttcatgattacactgtggatggctggatggtatttcaaccaaggtttcgctact
tgtctgggtctggtgtatatgtatgcccgtcaccagtatttctggggatattcggaagct
gctaaaaaaaggatccttggtttccggttgagtctgggggctctggccttgttggccgtc
ctagcagttctcgggattgcaaacagctttctggatgaatacctggacattgatatcgcc
aagaaactgaggcacttctaa