Myotis lucifugus (little brown bat): 102424113
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Entry
102424113 CDS
T07795
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1 isoform X1
KO
K05410
TANK-binding kinase 1 [EC:
2.7.11.10
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf04014
Ras signaling pathway
mlf04137
Mitophagy - animal
mlf04140
Autophagy - animal
mlf04620
Toll-like receptor signaling pathway
mlf04621
NOD-like receptor signaling pathway
mlf04622
RIG-I-like receptor signaling pathway
mlf04623
Cytosolic DNA-sensing pathway
mlf04657
IL-17 signaling pathway
mlf04936
Alcoholic liver disease
mlf05014
Amyotrophic lateral sclerosis
mlf05022
Pathways of neurodegeneration - multiple diseases
mlf05135
Yersinia infection
mlf05160
Hepatitis C
mlf05161
Hepatitis B
mlf05162
Measles
mlf05163
Human cytomegalovirus infection
mlf05164
Influenza A
mlf05165
Human papillomavirus infection
mlf05167
Kaposi sarcoma-associated herpesvirus infection
mlf05168
Herpes simplex virus 1 infection
mlf05169
Epstein-Barr virus infection
mlf05170
Human immunodeficiency virus 1 infection
mlf05171
Coronavirus disease - COVID-19
mlf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
102424113 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102424113 (TBK1)
04137 Mitophagy - animal
102424113 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
102424113 (TBK1)
04621 NOD-like receptor signaling pathway
102424113 (TBK1)
04622 RIG-I-like receptor signaling pathway
102424113 (TBK1)
04623 Cytosolic DNA-sensing pathway
102424113 (TBK1)
04657 IL-17 signaling pathway
102424113 (TBK1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
102424113 (TBK1)
05161 Hepatitis B
102424113 (TBK1)
05160 Hepatitis C
102424113 (TBK1)
05171 Coronavirus disease - COVID-19
102424113 (TBK1)
05164 Influenza A
102424113 (TBK1)
05162 Measles
102424113 (TBK1)
05168 Herpes simplex virus 1 infection
102424113 (TBK1)
05163 Human cytomegalovirus infection
102424113 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
102424113 (TBK1)
05169 Epstein-Barr virus infection
102424113 (TBK1)
05165 Human papillomavirus infection
102424113 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
102424113 (TBK1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
102424113 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
102424113 (TBK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102424113 (TBK1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102424113 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlf01001
]
102424113 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlf04131
]
102424113 (TBK1)
Enzymes [BR:
mlf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
102424113 (TBK1)
Protein kinases [BR:
mlf01001
]
Serine/threonine kinases: Other
IKK family [OT]
102424113 (TBK1)
Membrane trafficking [BR:
mlf04131
]
Autophagy
Xenophagy
Other xenophagy associated proteins
102424113 (TBK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
Pkinase_fungal
ABC1
CEP63
Kinase-like
DUF713
COG6_N
ubiquitin
Motif
Other DBs
NCBI-GeneID:
102424113
NCBI-ProteinID:
XP_006096914
Ensembl:
ENSMLUG00000009717
LinkDB
All DBs
Position
Unknown
AA seq
728 aa
AA seq
DB search
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLYAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPLSCSLSQGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQRMTAHKIYIHSYNTATVFHELVYKQTNISSANQELIYEGRRLV
LEPGRLGQHFPKTTEENPIFVVSRESLETVGLKYEKISLPKVHPRYDLDGDASMAKAMTG
VVCYACRIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLEFCLRSIQSMKV
YEKLLKTNLEATDLDEISDIHTKLLRLSSSRGTIENSLQDIESKLSPGGLLSDTWAHQEG
THPKDRHVEKLQVLLNWITEIYYQFKKDKAERKLPYNEEQIHKFDKQKLYYHATKAMTHF
TDECVKKYETFLAKSGEWMRKMLQLKKQLLSLTNQCLDIEEEISKYQDYTNELQETLPQK
MFAASSGIKHTMAPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDG
GLRNVDCL
NT seq
2187 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgacttatatgctatcaaagtattt
aataacataagcttccttcgtccagtagatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccatgtgggagtttatacactgttttagaagag
ccatctaatgcctatggactaccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatcttcgagaaaatggcatagtgcaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaagacggacagtctgtgtacaaactcaccgattttggtgca
gctagagaattagaagatgatgagcagtttgtttctttgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtgctaagaaaagatcatcagaagaaatatggagca
acagttgatctttggagcattggggtaactttttaccatgcagctactgggtcactgcca
tttaggccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaatcgactggagt
ggagacatgcctctttcttgtagtctttctcagggtcttcaagttctacttacccctgtt
cttgcaaacatccttgaggctgatcaggaaaaatgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccggatgataattcatgttttctcgctacaacgaatgaca
gctcataagatttatattcatagctataatactgctactgtatttcatgaactggtgtat
aaacaaaccaatattagttctgcaaatcaagaacttatatatgaaggacgccgcttagtt
ctagaacctggaagactaggacagcatttccctaaaactactgaggaaaatcctatcttt
gtagtaagccgggaatctctggagaccgtaggattgaaatatgaaaaaatttccctccct
aaagtacatccacgttatgatttagatggagatgctagcatggctaaggcaatgacagga
gttgtgtgttacgcctgtagaattgccagtaccttgctgctttatcaggaattaatgcga
aaggggatacgatggttgatagagttagttaaagatgattataatgaaactgttcacaaa
aagacggaagttgtgatcacattggaattctgcctcagaagcattcaaagtatgaaagta
tatgaaaaattgttgaaaaccaatctagaagcaacagacttagatgaaatttcagacata
cacaccaaattgttgagactttccagttctcggggaacaatagaaaacagtcttcaggat
attgaaagcaaattatctccaggtggattgctatcagatacatgggcccatcaagaaggc
actcatccaaaagatagacatgtagaaaagctacaagtcctgttaaattggatcacagag
atttactatcaattcaaaaaagacaaagcagaacgtaaattaccttataatgaagaacaa
atccacaaatttgataagcaaaaactgtattaccatgcaacaaaagcaatgacccacttc
acagatgaatgtgttaaaaagtacgagacatttttggctaagtcaggagaatggatgaga
aagatgcttcagcttaagaaacagttgttatccctaactaatcagtgtttagatattgaa
gaagaaatatcaaagtatcaagactatacaaatgagttacaagaaactttgcctcagaaa
atgtttgcagcctccagtggaatcaaacataccatggctccaatttatccatgttctaac
acattagtagaaatgactcttggtatgaagaagttaaaagaagagatggaaggggtggtt
aaagaacttgctgaaaataatcatattttagaaaggtttggctctttaaccatggatggt
ggccttcgcaatgttgactgtctttag
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