Myotis lucifugus (little brown bat): 102424778
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Entry
102424778 CDS
T07795
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf00230
Purine metabolism
mlf00670
One carbon pool by folate
mlf01100
Metabolic pathways
mlf01523
Antifolate resistance
Module
mlf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102424778 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102424778 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102424778 (GART)
Enzymes [BR:
mlf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
102424778 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
102424778 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
102424778 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_4
ATP-grasp_3
Dala_Dala_lig_C
RimK
Motif
Other DBs
NCBI-GeneID:
102424778
NCBI-ProteinID:
XP_006104331
Ensembl:
ENSMLUG00000012398
LinkDB
All DBs
Position
Unknown
AA seq
1009 aa
AA seq
DB search
MAARVLVVGSGGREHTLAWKLAQSPHVKQVLVAPGNAGTTGSGKISNTAISISDHSALAQ
FCKEENIEFVVVGPEAPLAAGIVGDLTAAGVRCFGPTAQAAQLESSKRFAKEFMDRHGIP
TARWRAFTEPEEARSFILSADFPALVVKASGLAAGKGVIVAESREEACRAVQEIMQDKAF
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDRGPNTGGMGAYCPAP
QVSKDLLLKIKNAILQRTVDGMQQEGTPYTGVLYAGVMLTRDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCAAPPVWLENRAAITVVMASQGYPGDYAKGVEVAGVAEA
QALGLEVFQAGTALKDGKVVTSGGRVLTVTAIRDTLVAALEGAKQGLAAIKFEGAVYRKD
IGGRAIAFLQQPRGLTYKDSGVDIAAGNLLVKKIKPFAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLVSGTDGVGTKLKIAQQCSQHGTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDVGTAAAVVAGIAEACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAVERDQQLP
RLESIAEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPHGCGDQTLGDLLLTPTR
IYSQSLLPVLRSGRVKAFAHITGGGLLENIPRVLPPRCGVELDARTWRVPTIFSWLQREG
RLSDEEMARTFNCGVGAALVVSEDLAEQVLRDVRQHQEEAWLIGRVVARPEGSPRVRVRH
LLDALQLSGPVLQNGSAHAPSSAPEKARVAVLISGTGSNLQALIDSTREPSSAAHIVVVI
SNKAAVAGLDRAARAGIPTRVLNHKLYKSRVDFDTAIDQVLTEFSADIVCLAGFMRILSG
PFVRKWNGRMLNIHPSLLPSFKGADAHEQALAAGVAVTGCTVHFVAEDVDAGRIILQEAV
PVRRGDTVATLSERVKVAEHRIFPAALQLVASGAVRLGEDGQLCWAQEE
NT seq
3030 nt
NT seq
+upstream
nt +downstream
nt
atggccgcccgagtgcttgtcgttggcagtgggggcagagagcacacgctggcctggaaa
ctggcgcagtctcctcacgtcaaacaggtgttggtcgcccccggaaatgcaggcactacc
ggctctgggaagatttcaaacactgccatctccatcagcgatcacagtgccctcgctcag
ttctgcaaagaggagaacattgaattcgttgttgttggaccagaggcacctctggctgct
ggcatcgtcggggacctgacggcggccggcgtgcggtgctttggccccacagcacaggcg
gctcagctagagtccagcaaaaggtttgccaaagagttcatggaccgacatggcatcccc
actgcccggtggagagccttcaccgagcccgaggaggcccgcagcttcatcctgagtgca
gacttccctgctctggtcgtgaaggccagcggcctggccgccgggaagggggtgatcgtg
gcagagagcagagaagaggcctgcagagccgtgcaggagatcatgcaggataaagctttt
ggagcagctggagaaacgattgtcattgaggaacttcttgaaggagaagaggtttcttgt
ctgtgcttcaccgatgggaggaccgtggctcccatgccccccgcgcaggaccacaagcgg
ctgctggagggagatcgcggccccaacacaggcgggatgggggcctactgcccagccccc
caggtctctaaggatttgctgctgaagattaaaaacgccatccttcagcggacagtggac
ggcatgcagcaggagggcacgccgtacacaggtgttctctacgcgggtgtgatgctcacc
agggatggcccgaaggttctggagtttaactgccgtttcggggacccggagtgccaggtg
atcctcccgctcctgaaaagtgatctctatgaggtgattcagtccaccctggacggcctg
ctctgcgcagctccgcctgtttggcttgaaaaccgggcggccatcactgtcgtcatggca
agtcagggctatcccggagactacgccaagggtgtggaggtagcaggggtcgccgaggcc
caggctttagggctggaggtgttccaggcaggcacagccctgaaagacggcaaagtggtg
accagcggagggcgagtcctcacggtgaccgccatccgggacactctcgtcgcagccctc
gaaggggccaagcaaggactggctgccatcaagtttgagggcgccgtctacaggaaggac
attggcggccgcgccatagcgttcctccagcagcccaggggcctgacgtacaaggactct
ggggtagacattgcagctggaaatctgctggtcaagaaaattaagcctttcgccaaagcc
acctccagaccaggctgtgatgtggatcttggaggttttgctggtctttttgatttgaaa
gcagcgggtttcaaagaccctctcctggtcagtggaacagatggcgttggcacgaaactg
aagatcgcccagcagtgcagccaacatggtaccattggccaagacctggttgccatgtgt
gtgaacgatatcctggcacaaggcgcggagcccctcttcttcctcgactatttttcctgt
gggaaacttgacgttggcacagctgcagcggttgttgctggcatcgccgaagcgtgcagg
aaagctgggtgtgccctcctcggaggggaaacggcagaaatgccggacatgtatccccct
ggggagtacgacctggccgggttcgccgtgggcgccgtggagcgggaccagcaactccct
cgcctggaaagcatcgccgaaggggacgtggttattggaatagcgtcatcgggtctccac
agcaacgggttcagccttgtgaggaagattgtggcgaaatcttcccttcagtactcctcc
ccggcaccccacggctgcggcgaccagaccttgggggacttactcctgactccgaccagg
atctacagccagtccctgttacctgtcttgcgttcgggtcgtgtcaaggcctttgcccac
atcacgggtggagggctgctggagaacatcccgcgggtcctccctccgaggtgcggggtg
gagttagatgcccggacctggagggtccccaccatcttctcgtggctgcagcgggaagga
cgcctctcggatgaggagatggccaggacctttaactgcggggtcggggctgccctcgtg
gtgtcagaggacctggcggagcaggtgctgagggacgttcggcagcaccaggaggaggcc
tggctgatcggcagggtggtggcccgccccgaaggctccccccgagtgagagtcaggcac
ctgctggatgccctgcagctgagcgggcccgtgctgcagaacggctccgcgcacgctccc
tcctctgccccggaaaaggccagagtggccgtcctcatctctgggacaggctcgaacctg
caggcgctgatagacagcacccgggagccgagcagcgccgcgcacatcgtcgtggtcatc
tccaacaaggccgcggtggccgggctggaccgagcggcgcgtgcgggcattcccaccagg
gtgctcaatcacaagttatataaaagccgtgtcgactttgacacggccattgaccaggtc
ctcacagagttctccgcggacatcgtctgcctggcagggttcatgaggatcttgtctggc
cccttcgtcaggaagtggaatgggagaatgctcaacatccacccgtccctgctgccgtcc
ttcaagggcgccgatgcccacgagcaagccctggccgccggcgtcgcggtgacggggtgc
accgtgcactttgtcgcggaagacgtggatgccgggcggatcattttacaagaagctgtg
ccggtgaggaggggcgacacggtggccaccctgtccgagcgggtgaaggtcgcggagcac
aggatcttccccgcggccctgcagctggtggccagcggcgccgtgcggctgggcgaggac
ggccagctctgctgggcccaggaggagtga
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