Myotis lucifugus (little brown bat): 102427329
Help
Entry
102427329 CDS
T07795
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf00562
Inositol phosphate metabolism
mlf01100
Metabolic pathways
mlf04014
Ras signaling pathway
mlf04015
Rap1 signaling pathway
mlf04020
Calcium signaling pathway
mlf04024
cAMP signaling pathway
mlf04070
Phosphatidylinositol signaling system
mlf04919
Thyroid hormone signaling pathway
mlf04933
AGE-RAGE signaling pathway in diabetic complications
mlf05205
Proteoglycans in cancer
Module
mlf_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
102427329 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
102427329 (PLCE1)
04015 Rap1 signaling pathway
102427329 (PLCE1)
04020 Calcium signaling pathway
102427329 (PLCE1)
04070 Phosphatidylinositol signaling system
102427329 (PLCE1)
04024 cAMP signaling pathway
102427329 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
102427329 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102427329 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102427329 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlf04131
]
102427329 (PLCE1)
Enzymes [BR:
mlf01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
102427329 (PLCE1)
Membrane trafficking [BR:
mlf04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
102427329 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
102427329 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
102427329
NCBI-ProteinID:
XP_023610603
Ensembl:
ENSMLUG00000016487
LinkDB
All DBs
Position
Unknown
AA seq
2296 aa
AA seq
DB search
MTSEEMAASDLIPVTQRKVVSSQSAADESSEKASGVSVPKTHTPGQSRPTSHTISKLNKP
NEETSGSNLPRILSTTRGKIMSDENSNETCWEKNMPDSVKNLNVNGNNILENRQCGLPQS
QFYKTCDSVVEEGLHLETGIPSSLERKVFPGIQLELDRPPTGIRPLGNQSATSRAHPDSD
LAVFHFHYELDRRMSDSVCSLSDNLILDDCGNCVSLPDVGREQKKNYMAYTCKLMELAKS
CDNENKQRQGDHCDALNDEYMCCEASCRKANVVCSSDSFCREGFTDSPSAETFLSHFEDF
PDNCEDVEDYFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLAAWSYI
DMKRSGSSLPCGRVTGQLSTVLIRQDGSPCLSEAQWYPIYNAVRRGEETEDTIGSLLHFF
TKLPASETAYERINVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGL
LSTFGGSTGRMMLKERQPGTSVANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQE
QNIYRRVLPVDYLCFLTQNLSTPECQRSLPCLKASISASILNSQNREHNALEDLVMRFNE
VSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKMWQFM
DQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCRVVPFCGVFLKELCEVLDGTSGL
VKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLEA
EDEDSPSEGSGSRKNSLKDKARCQFVIGDLLDTENDIFEQPKEWDPHGLEEPQKAFDHGI
ELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASPAS
AKAKLGMPAATSEPGKFPLLGNAGLSGLAEGVLDLFSVKAVYMGHPSIDIHTVCVQNKLS
SMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTKAVRKMRKFPDQRQQWL
RKQYVSLYQVRGVTFPLSSIASFSRYKSWQLDHQGSFSQLSHFLPEYMQRNNTLGIGTAK
KKKKILMRGESGEATDDEMATRKAKLHKECRSWSGSDPQDINEQEESEANAITSPPNPLP
SRRAHSLTTAGSPILAAGTSSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIKGGMKGFQSF
MVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRSGSESAPLYTNLTIDENTSG
LQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGVGI
LQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASENDE
SQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLRNPLGICRSVELDCWDG
DDGMPIIYHGHTLTTKIPFKDVIEAIDRSAFINSDLPIIISIENHCSLPQQRKMADIFKT
VFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQ
AQAYNGGNVNPPPTNNEEEEDEEDEYDYDYESLSDDNILEDRPESKSCSDKLQFEYNEEI
PKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTL
NASGSNRGKERKSRKSIFGNNPGRMSPGETASLNKTSGKSSYEGMRQAWEESSSPLSPAT
SLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLM
FWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDL
DNMEPAVYSLTIVSGQNVCPSNSTGSPCIEVDILGMPLDSCHFRTKPIHRNTLNPMWNEQ
FFFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFV
NSRRMEEISSGSSVPASLMFSTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQLLQ
QILTTEQDTKPIAADYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFPEEGY
VGRIVLKTQQENLEEKSIVQDDREVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQD
VIQQTLCKAKYSYSILSNPNPNDYVLLEEVVKDTANKKSSTPKPSQRVLLDQECVFQAQS
KWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTLPSQVLVSESVQN
KEERPVGGSDTMDYRQ
NT seq
6891 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgatctcatacctgtgactcagagaaaagtggtg
tcttctcagtcagctgcagatgaaagtagtgaaaaggcctcaggcgtcagtgttccaaag
acacatactcctgggcagagtaggccgacttctcataccatctcaaaactgaacaaaccc
aatgaggaaacttctggaagcaacttgcctaggattctctcaacaacaagggggaaaatc
atgagtgatgagaacagtaacgaaacgtgctgggagaaaaacatgcccgattctgtgaag
aaccttaacgtgaacggcaacaacatattggaaaaccgtcagtgtggtcttcctcagagc
cagttttacaaaacatgcgattctgttgtagaggaaggcctgcatttggaaactggaatc
ccttcttccctggaaagaaaggtgttccctgggattcaactggaactagacagacctccc
acgggcattcgtcccttaggaaatcaatcagcaaccagcagggcacaccccgacagcgat
ttggcggtatttcactttcattatgagcttgaccgaagaatgtcggacagtgtctgttcc
ctatcagacaacttgattttggatgattgtggaaactgtgtatcactgcctgatgttggt
agggagcaaaagaaaaattatatggcatatacttgcaaactgatggaattggcaaaaagc
tgtgataatgagaacaagcagcgacagggtgatcattgtgacgccttgaacgatgaatac
atgtgctgtgaagcttcctgccgaaaggccaacgtggtatgttctagtgacagcttctgc
agggagggttttactgatagtccatctgctgagacttttctgagccattttgaggacttc
cctgataattgtgaagacgtagaagattattttaaaagtaaaaaggagcgatctactttg
ttagtgaggagattttgtaaaaatgacagagaagttaagaaatctgtgtatactgggaca
agggcaattgtgaggactctgccttctggtcacattggactggcagcttggagttacatt
gatatgaagagaagtggaagctcgttgccttgtgggagagtaacgggccagctatcaaca
gtgctgattaggcaagatgggagcccatgtctgtcagaagcccagtggtatccgatctac
aatgcagtgagaaggggagaagaaacagaagatacaattggatctcttctccatttcttc
acaaagctcccagcctctgagacagcctatgaaaggattaatgttggtccctgcttaaag
caatgtgtccgagacaccgtatgtgagtaccgtgccaccctccaacggacatccatatct
cagtacatcacgggttctctcctagaagcaaccacatctttaggagcaagaagtgggctt
ctcagtacttttggaggatccaccggacgaatgatgctgaaagaacgccaaccgggcacc
tctgtggccaattccagtgccctcccttcaagttcagctgggatcagcaaggagctgatt
gatctgcagcccctcatccagttccccgaggaagtcgccagcatcctgatggagcaggaa
cagaatatctaccgaagggtcttgccggttgactatctttgcttcttgacccagaacttg
agcactccagaatgtcagaggtccctgccctgcctcaaagcatccatctcagcatcaatt
cttaactcccagaacagagagcacaatgcccttgaagatcttgtgatgagatttaatgag
gtgagctcctgggtgacgtggctgatcctcacagctggctccatggaggagaagcgggaa
gtcttctcatatttggtgcatgtggccaaatgctgctggaacatgggcaactacaacacc
gtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtggcagttcatg
gaccagtctgacctggagaccatgaggagtctgaaggatgccatggctcagcacgaatcc
tcctgcgagtacaggaaggtggtgacgcgggcgctgcacatcccgggctgcagggtggtc
ccgttctgcggggtgtttctgaaggagctctgcgaagtgctggacggcacctccggcctc
gtgaagctctgccccagatacaattcccaggaggaaactctagagtttgtagccgactac
agtggacaagataattttttacaacgcgtgggacaaaatggcttgaagaattcggaaaaa
gagtccaccgtcaacagcatctttcagatcatcaggagctgcagccgcagtctggaggcg
gaggacgaggacagccccagtgaggggagcggctctcggaaaaactccctgaaggacaaa
gctcgctgccagtttgtaattggagatttgctggatacagaaaatgacatctttgagcag
cccaaagagtgggaccctcatggattagaagagccacagaaggcctttgaccacgggata
gagctcatcccatggtacgtgctgtccatccgagctgacgtgcaccagttcctgctgcag
ggggccacggtcatccactatgatcaggacacacacctctctgcccgctgcttcctccaa
cttcagcctgacaatagcaccttgacctggataaagcccaccacggcctccccagccagt
gcaaaagcaaaacttggtatgcctgctgccacgtccgagcctggcaaattcccgttactg
ggcaatgctggattaagtggcctggcggagggggtcttggatctgttttccgtaaaggct
gtgtacatggggcaccctagcattgatatacacactgtgtgtgttcagaacaaactgagt
agcatgtttctctcggagactggtgtgacactgctctatgggcttcagaccacggacaat
agattactgcactttgtggcaccaaagcacacagctaaaatgctcttcagtggattgttg
gaactcactaaagctgtgagaaagatgaggaagttccctgaccaaagacagcagtggctg
cggaaacagtacgtcagcctctatcaggtaaggggtgtgaccttccctctctcctcaata
gcatcattctccaggtataaatcttggcaactagaccaccagggctcattctcccagctc
agtcacttcctacctgagtacatgcagaggaacaacaccctgggcatcggtactgccaag
aagaagaagaaaatccttatgaggggtgagagtggagaggccaccgacgatgagatggcc
acccgaaaggccaaactgcacaaagagtgtcgaagctggagtggctctgatcctcaggac
attaacgagcaagaggagtcagaggcgaatgccatcacaagcccgcctaaccctctccct
tccagaagagcccactctctgaccacggctgggtcccccatcttggctgccgggacgtca
tctcccatcaggccagtgtcctcccctgtgctgtcttcaaacaagagcccgtccagtgcc
tggagcagcagcagctggcacggccgcatcaaaggaggaatgaaaggcttccagagcttc
atggtttccgacagcaacatgagttttgttgaatttgtggagctgttcaaatccttcagt
gtaaggagccgcaaggacctgaaggatctcttcgacctctacgccgtgccctgcaaccgg
tcaggctctgagtcggccccgctctacaccaacctaaccattgatgagaacaccagcggt
cttcagcctgatctagatttgttgaccagaaatgtctcagatttggggctgttcattaag
agtaaacagcagctgtcagacaaccagaggcagatctctgacgccattgctgctgcaagc
atcgtgacgaatggcactggggtcgagagcacatccctgggcgtgtttggggtcggcata
cttcagctcaatgacttcctagtgaactgccagggagaacactgcacttacgatgaaatc
ctcagcatcatccagaagtttgagcctagcattagtatgtgtcatcagggcctaatgtca
tttgaaggatttgcaaggtttctgatggataaagacaactttgcttcggaaaacgatgaa
tcacaggagaacattaaagaattacagctgcccctctcctactattacattgaatcttca
cacaatacctacctcacaggccatcagctcaaaggagaatcctcagtagaactctacagc
caggtactgagaaatccccttggaatctgtaggagcgtagagttggactgctgggacgga
gatgatgggatgcccatcatttaccatggacatacactgacaaccaagatccccttcaag
gacgtgatcgaagccattgatcgcagtgccttcatcaactctgacctgccaatcatcata
tcaattgaaaaccactgttcattgcctcagcaacgaaaaatggcagacattttcaagact
gtatttggagaaaaactggtggctaagttcttatttgaaagtgatttctcagatgatcca
atgcttccttcccctgaccaacttagaaggaaggtgcttctcaaaaataagaagctaaaa
gcccaccagacgccggtggatatcttaaagcaaaaggctcatcagttagcatccatgcaa
gctcaggcttacaatggtgggaatgtcaaccccccacctactaataatgaggaggaggaa
gatgaagaggacgagtacgattatgactatgaatctctctctgatgataacattctagaa
gacagacctgaaagcaaatcgtgtagcgacaagcttcagtttgagtataatgaagaaatc
cccaagaggataaagaaagcagacaactctgcttgcaacaaaggaaaggtgtatgacatg
gagttgggagaagaattttatcttcctcagaataaaaaagaaagcagacagattgcacca
gagctttccgaccttgtcatctattgccaagcagtaaaattcccaggcctgtcaactcta
aatgcatctggctctaacagaggaaaagaaaggaaaagcaggaagtccatttttggcaac
aatccgggcagaatgagccctggggagacggcatcacttaacaaaacatctggaaaaagt
tcctatgaaggaatgcgacaggcctgggaggagtcttcttcccccctcagcccagccacg
tccctcagcgctatcattagaactcccaaatgttaccatatctcatcgctgaatgaaaat
gccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacaccgcctgtcag
ctgctgaggacttacccggctgccacccgcatcgactcctccaaccccaaccccctcatg
ttctggctgcacgggatacagctcgtggcactcaactaccagacagatgatctcccttta
catttaaacgctgccatgtttgaggccaacggtggctgtggctatgtgttgaaaccccca
gttctgtgggacaagaactgccccatgtatcagaagttttctcccctggaaagagacctg
gacaacatggagcccgccgtctactctttgactattgtctctggccagaacgtgtgcccg
agcaacagcacaggaagcccgtgcatcgaggtcgacatcctgggcatgccgctggacagc
tgccacttccgcacgaagcccatccaccggaacactctgaaccccatgtggaacgagcag
tttttcttccgggttcactttgaagacctcatatttcttcgttttgcagttgtggaaaac
aacagctcggcggtcactgctcagaggatcatcccactcaaggctctaaagcgaggatat
cgacatcttcagctgcgaaacctccacaatgaagtcttggaaatctctagtttattcgta
aacagcagaaggatggaagaaatctcctctggcagttccgtgccggcctctttgatgttt
agtacagaagaaagaaaatgtttgcagactcacagagtcacggtgcatggcgtcccaggt
ccggagcccttcactgttttctctataaatggaggcaccaaggcaaagcaacttctccag
caaattctgaccactgagcaagacaccaaacctattgccgcagactactttttgatggaa
gaaaaatattttatatctaaagaaaagaatgaatgcagaaaacagccgttccagagggcc
attggtcccgaggaagagatcgtgcagattttaagcagctggtttccagaagagggctat
gttggcaggattgtcttaaaaacccagcaggaaaacctggaagagaaaagcattgttcaa
gatgacagagaggtgatcttgagctcggaggaggagagtttctttgtccaagtgcacgac
gtttctccagagcagccgcggacagtcatcaaagcgccgcgcgtcagcaccgcacaggac
gtcattcagcagaccttatgcaaagccaagtactcctacagcatcctgagcaaccccaac
ccgaacgactacgtacttttggaagaggtggtgaaagacacagccaacaagaagtcttct
acccccaagccctcccagcgggtccttttggatcaggagtgtgtgtttcaagcccaaagc
aagtggaaaggtgcaggaaaattcatccttaagctaaaggagcaagtgcaggcatccaga
gaagacaagagaaaaggcatttcttttgcaagtgaattcaagaagttcaccaagtcaact
aaacagccccgaggactcacattaccttctcaggtcttggtttcggaaagtgtccaaaac
aaagaggagagacctgtgggtggcagcgacacgatggactatcgacagtga
DBGET
integrated database retrieval system
