Myotis lucifugus (little brown bat): 102429332 Help Entry 102429332         CDS       T07795                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism mlf  Myotis lucifugus (little brown bat) Pathway mlf01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:mlf00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102429332 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:mlf03032]     102429332 (TOP2A)    03036 Chromosome and associated proteins [BR:mlf03036]     102429332 (TOP2A) Enzymes [BR:mlf01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      102429332 (TOP2A) DNA replication proteins [BR:mlf03032]  Eukaryotic type   DNA Topoisomerases    102429332 (TOP2A) Chromosome and associated proteins [BR:mlf03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     102429332 (TOP2A)   Centrosome formation proteins    Centriole proteins     102429332 (TOP2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  102429332 NCBI-ProteinID:  XP_014321722 Ensembl:  ENSMLUG00000007831 LinkDB All DBs Position Unknown AA seq 1482 aa AA seqDB search MEVSPLQPVNENMQINKKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQM WVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN GKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET ASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVR RAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVCL TMSEKGFQQISFVNSIATSKGGRHVDYVTDQIVTKLVDVVKKKNKGGVAVKAHQVKNHMW IFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQV QLNKKCSAVKHNRIKGIPKLDDANDAGSRNSADCTLILTEGDSAKTLAVSGLGVVGRDKY GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMSFYSLPEFEEWKNS TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQTDDR KEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDG LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDNTLKFLYDDNQRVEPEWY IPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIEE LASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYH TDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRD FYELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRG YDSDPVKAWKEAQQKVTEEEENEESDNEKETEKSDSASGPTFNYLLDMPLWYLTKEKKDE LCKQRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGKGGKGKGK KTQMAEVLPSPSGKRVVPRVTIEMKAEAEKKIRRKIKNENTEGSPQEDSVEPESLKQRLE KKQKREPGNKAKKQTTLPFKPIQKGKKRNPWSDSESDMSGNESDFDVPPREVEPRRAATK AKFTVDLDSDEDFSDIDKKSEDEDFVPSDASPVKTKTSPKHTNKELKPQKSTTSGQSSTS TTGAKKRAAPKGTKKDPSLTSDVPQKPDPPKTKIRRKRKASSSDDSDSNFEKMISKAVTS KKSKGESDDFHMDLDSAVAPRVKSGRTKKPIKYLEESDEDLF NT seq 4449 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtcaccattgcagcctgtaaatgagaatatgcaaatcaacaaaaagaaaaat gaagatgctaaaaaaagactgtctattgaaagaatctatcaaaagaaaacgcaactggaa catattttgctccgtccagacacctacattggctctgtggaattagtgacccagcaaatg tgggtttacgatgaagatattggcattaactatagggaagtcacttttgttcctggtttg tacaagatctttgatgagattctagtcaatgctgcagacaacaaacaaagggacccaaaa atgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaataat ggaaaaggtattcctgttgttgaacacaaagtagagaagatgtatgtcccagctctcatc tttggacagctcttaacttctagtaactatgatgatgatgaaaagaaagtaacaggtggt cgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaaaca gccagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggagagcc ggtgagatggaactcaagccctttaatggagaagattatacatgtattactttccagccc gatttgtctaaatttaaaatgcaaagcctagacaaagacattgttgcactaatggttaga agagcatatgatattgctggatccactaaagatgtcaaagtctttctcaatggaaataag ctgccagtgaaaggattccgtagctatgtggatatgtatttgaaggataaggtagatgaa actggcaatccattgaaagttatccatgaacaagtaaaccacaggtgggaagtatgttta acaatgagtgaaaaaggctttcaacaaattagctttgtcaacagcattgctacttccaag ggtggcagacatgttgattatgtaactgatcagattgtgactaaacttgttgatgttgtg aagaagaagaacaagggcggtgttgcagtaaaagcacatcaggtgaaaaatcacatgtgg atttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaacatg actttacaagccaagagttttggatcaacatgccaattaagtgaaaaattcatcaaagct gcaattggctgtggtattgtagaaagcatactaaactgggtgaagtttaaggctcaagtc cagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaactt gatgatgccaatgatgcagggagccgaaactctgctgactgcacacttattctgactgag ggagactcagctaaaaccttggctgtttcaggcctaggtgtggttgggagagacaagtac ggggttttccctcttagaggaaaaatactcaatgttcgagaagcttctcataaacagata atggaaaatgccgaaattaacaatatcataaagattgtgggtcttcagtacaagaaaaac tatgaagatgaagattcactgaagactcttcgttatgggaagataatgattatgacagat caggaccaagatggttcccatatcaaaggtttgctgattaattttatccatcacaactgg ccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtgtct aaaaacaagcaagaaatgtctttctatagtcttcctgaatttgaagaatggaagaattct acaccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcacatca aaagaagctaaagaatactttgcagatatgaaaagacatcgtatccaattcaaatattct ggtcctgaagatgatgctgcgatcagcctggcctttagcaaaaaacagacagatgatcga aaggaatggttaactcatttcatggaagacagaagacaacggaagttacttggccttcct gaggattacttgtatgggcaaactaccacatatctgacgtacaacgacttcataaacaag gaacttatcctattctcaaattctgataacgagagatctatcccatctatggtggatggt ttgaaaccaggtcagagaaaggttttgtttacgtgtttcaaacggaatgacaagcgagag gtgaaggttgcccaattagctgggtcagtggctgagatgtcctcttatcatcatggtgag atgtcactaatgatgacgattatcaatttggctcagaattttgtgggtagcaataatctg aacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattctgct agtcctcgatacatcttcacaatgctcagtcctttggctcggttgttatttccaccaaaa gatgataacacattaaagttcttatatgatgacaaccaacgtgtggagcccgaatggtat attcctattatacccatggtgctgataaatggtgctgaaggaattggtactgggtggtcc tgcaaaatccccaactttgatattcgtgaagttgtgaataacatcaggcgtttgatggat ggagaagaacctttgccaatgcttccaagttataagaacttcaagggtactattgaagag ctggcttcaaatcaatatgtgattagtggtgaagtggctattcttaattccacaaccatt gaaatctcagagcttcccatcagaacatggacccagacatacaaagaacaggtgctagaa cccatgttgaatggcactgagaagacgccacctctcataacagattatagggaatatcat acagataccactgtgaagtttgttgtgaagatgactgaagaaaaactggctgaggctgag agagttggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatggtg ctttttgaccacgtaggctgtttaaagaaatatgacacggtgcttgatattctaagagac ttctatgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatgctt ggcgctgaatctgctaaactgaacaatcaggcccgctttatcttagagaaaatagatggc aaaataatcattgaaaataagcccaaaaaagaattaattaaagttttgattcagagggga tatgattcggatcctgtgaaggcttggaaagaagcccagcaaaaggttacagaagaagaa gaaaatgaagagagtgacaatgaaaaggaaactgaaaaaagtgactctgcatctggacca actttcaactaccttcttgatatgccactttggtatctaactaaagaaaagaaagatgaa ctgtgtaaacaaagaaatgaaaaagaacaagagctggaaacattaaagagaaaaagtcca tcagatttgtggaaagaagacttggctgcttttattgaagagctggaggctgttgaagcc aaggaaaaacaagatgaacaagtaggacttcctgggaaaggggggaaaggaaaagggaaa aaaacacaaatggctgaagttttgccttctccaagtggaaaaagagtcgtcccccgggtg accatagagatgaaagcagaggcagaaaagaaaattagaaggaaaataaagaatgaaaat actgaaggaagccctcaagaggacagtgtggaaccagaaagcctaaaacaaagattagag aagaaacagaaaagagaaccaggtaacaaagcaaagaaacaaaccacattgccatttaaa ccaatccaaaaaggaaagaagagaaacccctggtctgattcggaatcagatatgagcggt aatgaaagtgattttgatgtccctccacgagaagtagagccacgaagagcagcaacaaaa gccaaattcacagtggatttggattcagatgaagatttctcagatattgataaaaaaagt gaagatgaagattttgtcccatcagatgctagtccagttaagaccaaaacttccccaaaa catacgaacaaagaactaaagccacagaagagcaccacatcaggtcagtcttccacctcc actacaggtgccaaaaaaagggctgcaccaaaaggaactaaaaaggatccaagcttgact tctgatgtccctcaaaagccagatccccccaaaaccaagattcgccgcaaaaggaaggca tcctcttctgatgattccgactctaattttgagaaaatgatttctaaagcagtcacaagc aagaaatccaagggggagagtgatgacttccatatggacttggactcagctgtggctcct cgggtaaaatctggacggacaaagaaacctattaagtacctcgaagaatcagatgaagat ctgttttaa

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