KEGG   Myotis lucifugus (little brown bat): 102429560
Entry
102429560         CDS       T07795                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
mlf  Myotis lucifugus (little brown bat)
Pathway
mlf04010  MAPK signaling pathway
mlf04022  cGMP-PKG signaling pathway
mlf04137  Mitophagy - animal
mlf04141  Protein processing in endoplasmic reticulum
mlf04151  PI3K-Akt signaling pathway
mlf04210  Apoptosis
mlf04211  Longevity regulating pathway
mlf04261  Adrenergic signaling in cardiomyocytes
mlf04668  TNF signaling pathway
mlf04720  Long-term potentiation
mlf04722  Neurotrophin signaling pathway
mlf04725  Cholinergic synapse
mlf04728  Dopaminergic synapse
mlf04911  Insulin secretion
mlf04912  GnRH signaling pathway
mlf04915  Estrogen signaling pathway
mlf04918  Thyroid hormone synthesis
mlf04922  Glucagon signaling pathway
mlf04925  Aldosterone synthesis and secretion
mlf04926  Relaxin signaling pathway
mlf04927  Cortisol synthesis and secretion
mlf04928  Parathyroid hormone synthesis, secretion and action
mlf04932  Non-alcoholic fatty liver disease
mlf04934  Cushing syndrome
mlf04935  Growth hormone synthesis, secretion and action
mlf05010  Alzheimer disease
mlf05012  Parkinson disease
mlf05014  Amyotrophic lateral sclerosis
mlf05020  Prion disease
mlf05022  Pathways of neurodegeneration - multiple diseases
mlf05030  Cocaine addiction
mlf05031  Amphetamine addiction
mlf05034  Alcoholism
mlf05161  Hepatitis B
mlf05163  Human cytomegalovirus infection
mlf05166  Human T-cell leukemia virus 1 infection
mlf05203  Viral carcinogenesis
mlf05207  Chemical carcinogenesis - receptor activation
mlf05215  Prostate cancer
mlf05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlf00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102429560 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102429560 (ATF4)
   04668 TNF signaling pathway
    102429560 (ATF4)
   04022 cGMP-PKG signaling pathway
    102429560 (ATF4)
   04151 PI3K-Akt signaling pathway
    102429560 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    102429560 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    102429560 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102429560 (ATF4)
   04922 Glucagon signaling pathway
    102429560 (ATF4)
   04912 GnRH signaling pathway
    102429560 (ATF4)
   04915 Estrogen signaling pathway
    102429560 (ATF4)
   04926 Relaxin signaling pathway
    102429560 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    102429560 (ATF4)
   04918 Thyroid hormone synthesis
    102429560 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    102429560 (ATF4)
   04925 Aldosterone synthesis and secretion
    102429560 (ATF4)
   04927 Cortisol synthesis and secretion
    102429560 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102429560 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    102429560 (ATF4)
   04728 Dopaminergic synapse
    102429560 (ATF4)
   04720 Long-term potentiation
    102429560 (ATF4)
   04722 Neurotrophin signaling pathway
    102429560 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    102429560 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    102429560 (ATF4)
   05203 Viral carcinogenesis
    102429560 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    102429560 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102429560 (ATF4)
   05161 Hepatitis B
    102429560 (ATF4)
   05163 Human cytomegalovirus infection
    102429560 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102429560 (ATF4)
   05012 Parkinson disease
    102429560 (ATF4)
   05014 Amyotrophic lateral sclerosis
    102429560 (ATF4)
   05020 Prion disease
    102429560 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    102429560 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    102429560 (ATF4)
   05031 Amphetamine addiction
    102429560 (ATF4)
   05034 Alcoholism
    102429560 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102429560 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102429560 (ATF4)
   04934 Cushing syndrome
    102429560 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mlf03000]
    102429560 (ATF4)
Transcription factors [BR:mlf03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    102429560 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 KIF21A DUF3450 DUF724 Asd-4 DUF4407 DUF1826 OVT1 Baculo_F AAA_13
Other DBs
NCBI-GeneID: 102429560
NCBI-ProteinID: XP_006110033
Ensembl: ENSMLUG00000027798
UniProt: G1QEU7
LinkDB
Position
Unknown
AA seq 347 aa
MTEMSFLSSEVLVGGLMSPFNQSGLGAEESLDLLDDYLEVAKNLKPHGFSSDKAKAGSSE
WLAVDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDALLSLGDLDTMPDELLATLDDPC
DLFDPLDQEINKEPPHTMNPIGHLPESLLKTDQVAPFTFLQPLPLSPEALSCTPDHSFSL
ELGSEVDISEGERKSDSTTYIPIKEEDVTSDNDSGICMSPESYLGSPQNSPSTSRASPNR
NLLSSAPPCGSAGPKPYDPPVEKVVAAKVKGEKLDKRLKKMEQNKTAATRYRQKKRAEQE
ALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKRAP
NT seq 1044 nt   +upstreamnt  +downstreamnt
atgaccgagatgagcttcttgagcagcgaggtgttggtggggggcttgatgtcccccttc
aaccagtcgggtttgggggctgaagaaagcttagatctcttagacgactacctggaggtg
gccaagaacttgaaaccccatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtgcctcagacaacggcaaggaggatgccttctcg
gggacagattggatggtggagaaaatggatctcaaggagtttgacttcgatgccctgtta
agtttaggtgacctggacaccatgcctgatgagcttttggccacgttggatgacccctgt
gacctcttcgaccccctagaccaggagattaataaggagcccccccataccatgaaccca
attggccatcttccagaaagtttgctaaaaactgaccaggttgcccccttcaccttcctg
caacctcttcccctttccccggaggccctgtcctgcactccggatcattcctttagttta
gagctgggaagtgaagttgacatctctgaaggagagagaaaatcagactccactacttat
attcccataaaggaggaggatgtcacctcagacaatgacagtggcatctgtatgagccct
gagtcctatctgggctctccccagaatagtccctccacctccagggcctccccaaacagg
aatctgctgtcttcagctcccccctgtgggtctgctggccccaaaccctatgaccctccc
gtagagaaggtggtagctgcaaaagtaaagggtgagaaactagataaaaggctgaaaaaa
atggagcagaacaagacagcagctactaggtaccgccagaagaagagagcagagcaggag
gccctcaccggtgagtgtaaagagctagaaaagaaaaacgaggctctgaaagagaaggcc
gattccttggccaaggagatccagtacctgaaagatctgatagaggaagtccgcaaggcc
aggggaaagaaaagggccccctag

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