Myotis lucifugus (little brown bat): 102433074 Help Entry 102433074         CDS       T07795                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism mlf  Myotis lucifugus (little brown bat) Pathway mlf00220   Arginine biosynthesis mlf00330   Arginine and proline metabolism mlf01100   Metabolic pathways mlf04020   Calcium signaling pathway mlf04081   Hormone signaling mlf04145   Phagosome mlf04371   Apelin signaling pathway mlf04713   Circadian entrainment mlf04730   Long-term depression mlf04926   Relaxin signaling pathway mlf04970   Salivary secretion mlf05010   Alzheimer disease mlf05014   Amyotrophic lateral sclerosis mlf05022   Pathways of neurodegeneration - multiple diseases mlf05410   Hypertrophic cardiomyopathy mlf05412   Arrhythmogenic right ventricular cardiomyopathy mlf05414   Dilated cardiomyopathy mlf05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:mlf00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     102433074 (NOS1)    00330 Arginine and proline metabolism     102433074 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     102433074 (NOS1)    04020 Calcium signaling pathway     102433074 (NOS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     102433074 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     102433074 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     102433074 (NOS1)   09154 Digestive system    04970 Salivary secretion     102433074 (NOS1)   09156 Nervous system    04730 Long-term depression     102433074 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     102433074 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102433074 (NOS1)    05014 Amyotrophic lateral sclerosis     102433074 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     102433074 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     102433074 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     102433074 (NOS1)    05414 Dilated cardiomyopathy     102433074 (NOS1)    05416 Viral myocarditis     102433074 (NOS1) Enzymes [BR:mlf01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      102433074 (NOS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  102433074 NCBI-ProteinID:  XP_023616172 Ensembl:  ENSMLUG00000009207 LinkDB All DBs Position Unknown AA seq 1424 aa AA seqDB search MENHMFSVQQIQPNVISVRLFKRRVGGLGFLVKERVSKPPVIVSDLIRGGAAEQSGLIQA GDIILAVNGQPLVDMSYASALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTRPLGPPTTAVDLSHQSSACKEQPLAVDGATGPSNGPQHAQDNGPEAGSLSHTNGLDP AKKNAGAARQCSEEHNELLKEIKPVLNLLTSADRGINGGGPTKAETKDAEVQVDRDLDAK SHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQAPASGRQSPPKNGSPSKCPRFLK VKNWETDVVLTDTLHLKSTLETGCSERICMGSVMQPSQQIRRPEDVRTKEQLFPLAKEFI DQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRCVGRIQWS KLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRIDSKHDFRVWNSQLIRY AGYKQPDGSILGDPANVEFTEICILQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVL EVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNS RYNILEEVAKKMNLDTRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHM ENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHLWKGTNGT PTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYGTETGKSQAYAKTLCEIFKHAFD AKVVAMEDYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSYK VRFNSVSSYSDFHKSSGNGPNHRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTL LEELGGERILKMKEGDELCGQEEAFRTWAKKVFKTACDVFCVGDDVNIEKANNSLISNDR SWKRNKFRLTYVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGH QELQYQPGDHLGVFPGNQEDLVNALIERLEDAPPINQLVKVELLEERSTALGVIRNWTDE RRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQQLLVLSKGLQEYEEWKWSK NPTIVEVLEEFQSVQMPATLLLTQLSLLQPRYYSISSSPDMYPEEVHLTVAIVSYRTGDG EGPVHHGVCSSWLNQIQSDEVVPCFVRGAPGFHLPRNPQVPCILIGPGTGIAPFRSFWQQ RQFDIQHKGMSPCPMILVFGCRQSKVDHIYREETLQARSAGVFRELYTAYSREPDRPKKY VQDILQEKLAEPLYQALKEQGGHIYVCGDVTMAADVLKAIQRIMAQQGKLSVEDAGVFIS RLRDDNRYHEDIFGVTLRTYEVTNRLRSESSIAFIEESKKDTDE NT seq 4275 nt NT seq  +upstreamnt  +downstreamnt atggagaatcacatgttcagtgtccagcaaatccaacccaacgtgatttctgtccgcctc ttcaagcgcagagtggggggcttggggttcctggtgaaggagcgggtgagcaagcccccc gtgatcgtctccgacctgattcgagggggtgccgccgagcagagcggcctcatccaggcc ggagacatcatcctcgcggtcaacggccagccgttggtggacatgagctacgccagcgcc ctggaggtgctcaggggcattgcttccgagacccacgtggtcctcattctgaggggcccg gagggcttcaccacgcacctggagaccacctttactggggacgggacccccaagaccatc cgggtgacacggcccctgggcccccccaccacggctgtcgatctgtcacaccagtcgtca gcctgcaaagagcagccgctggcggtggacggggccacaggccccagcaacgggccccag cacgcccaggacaacgggccagaagccggctcgctgtcccacaccaacggcctggaccct gccaagaagaatgccggggccgcccgtcagtgcagtgaggagcacaatgagttgctcaaa gagatcaagcctgtgctgaaccttctcacctcggccgacagagggatcaacggaggggga cctaccaaggcggagacaaaagatgcagaagttcaggtggacagagacctggatgccaag tcacacaaacctctgcccctcggcgtggagaatgaccgtgtcttcaatgacctgtggggg aagggcaacgtgcctgtggtcctcaacaacccgtattcagagaaggagcaggcccctgcc tcgggaagacagtcccccccaaagaacggcagcccctccaagtgcccccgcttcctcaag gtcaagaactgggagactgacgtggttctcacggacaccctccaccttaagagcacgttg gaaacgggatgcagcgagcgcatctgtatgggctccgtcatgcagccttctcagcagata cggaggcctgaggacgtccgcactaaagagcagctcttccctctcgccaaagagttcatt gatcagtactactcgtccattaaaagatttggctccaaagcccacatggagaggctggaa gaggtgaacaaggagatagaaaccaccagcacctaccagctcaaagacacagagctcatc tatggggccaagcacgcctggaggaatgcctcccgctgcgtcggcaggatccagtggtcc aagctgcaggtgtttgatgcccgcgactgcaccacggctcatgggatgttcaactacatt tgcaaccacatcaagtatgccaccaacaaagggaacctcaggtccgccatcaccatattt ccccagaggatcgacagcaagcacgatttccgagtctggaactcccagcttatccgctat gctggctacaagcagcctgatggctccatcctgggggacccagccaatgtggagttcaca gagatctgcatcctgcagggctggaagcccccgagaggccgcttcgacgtcctgccactc ctgctccaggccaatggcaatgaccccgagctcttccagatccccccagagctggtgctg gaagtgcccatcaggcaccccaagtttgagtggttcaaggacctggggctgaagtggtac ggcctccccgctgtgtccaacatgctgctggagattggcggcctggagttcagcgcctgt cccttcagcggctggtacatgggcacggagattggcgtccgcgactactgtgacaactct cggtacaacatcctggaggaagtggccaagaagatgaacttggacacgaggaagacgtcc tccctgtggaaggaccaggcgctggtggagatcaacattgccgttctctacagcttccag agtgacaaagtgaccatcgtcgaccaccactcggccaccgagtccttcattaagcacatg gagaacgaataccgctgccgggggggctgtccggcagactgggtgtggatcgtgcccccc atgtctggcagcatcacccctgtcttccaccaggagatgctcaactaccggctcaccccc tccttcgaataccagccggacccttggaacacccacctctggaaaggcaccaacgggacc cccaccaagcggcgagccatcggcttcaagaagctggcagaagccgtcaagttctcagcc aagctgatggggcaggcaatggccaagagggtcaaggcgaccatcctgtatggcacagag acgggtaaatcgcaggcctatgccaaaaccctgtgtgagatcttcaagcacgccttcgat gccaaggtggttgccatggaagactatgacattgtgcacctggaacatgaaacgctggtc ctggtggtcaccagcacctttggcaatggagacccccctgaaaatggggagaaattcggc tgtgctttgatggaaatgaggcaccccaactctgtgcaggaggaaaggaagagctacaag gtcaggttcaatagtgtttcctcctattccgacttccacaaatcatcaggcaatgggccg aaccacagagacaactttgagagcaccggccccctggcaaacgtgaggttctcagtgttt ggccttggctcgagggcatacccgcacttctgcgcctttggccacgctgtggacaccctc ctggaagagctgggaggagagaggatcctgaagatgaaggaaggggatgagctctgtggt caggaggaggcgttcaggacctgggccaagaaggtcttcaagacagcctgtgacgtgttc tgcgtgggagatgatgtcaacattgagaaggcgaacaactccctcatcagcaatgaccgc agctggaagaggaacaagttccgcctcacctatgtggccgaagctccagagcttacacaa ggtctatccaacgtgcacaagaagcgggtctcagctgctcgtcttctcagccgtcaaaac cttcagagccctaaatccagccggtcaaccatcttcgtgcgtctccacacaaatgggcat caggagctgcagtaccaacctggggaccacttgggcgtcttccctggcaaccaggaggac ctggtgaatgccctgatcgagcggctggaggatgcgccccctatcaaccagctggtgaaa gtggagctgctggaagagcggagcacggctctgggagtcatccgcaactggacggatgag cgccgcctcccgccctgcaccatcttccaggccttcaagtactacctggacatcaccacg ccgcccacgcccctgcagctgcagcagttcgcctccctggccaccagcgagaaagagaag cagcagctgctggtcctcagcaagggcttgcaggagtacgaggaatggaaatggagcaag aaccccaccatcgtggaggtgctggaggagttccagtccgtccagatgcctgccaccctg ctcctgacccagctgtcccttctgcagcctcgttactactccatcagctcctccccggac atgtaccccgaggaggtgcacctcaccgtggccatcgtctcttaccgcactggagatgga gaaggaccagttcaccacggcgtgtgctcctcctggctcaaccagatacagtccgacgaa gtggtcccctgtttcgtgagaggagcgcccggcttccacctgccccgaaacccccaagtg ccctgcatcctgattggcccgggcaccggcatcgcccctttccgaagcttctggcagcag cggcagtttgatatccagcacaaaggaatgagtccctgccccatgatcctggtcttcggg tgccggcagtccaaggtggaccacatctacagggaggagaccctgcaggcccggagcgcg ggggtcttcagagaactgtacacggcctactcccgggagcccgacagaccaaagaagtac gtgcaggacatcctgcaggagaagctggcggaaccgctgtaccaggccctgaaggagcag gggggccacatctatgtgtgcggggacgtcaccatggccgccgacgtcctcaaggccatc cagcgcatcatggcgcagcaggggaagctctcggtggaggacgcgggcgtgttcatcagc cggctgagggatgacaaccgctaccatgaggatatcttcggggtcaccctgcgaacgtat gaagtgaccaaccgccttaggtctgaatcctcgatcgccttcattgaggagagcaaaaag gacacggacgagtaa

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