Myotis lucifugus (little brown bat): 102433832
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Entry
102433832 CDS
T07795
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf04217
Necroptosis
mlf04380
Osteoclast differentiation
mlf04620
Toll-like receptor signaling pathway
mlf04621
NOD-like receptor signaling pathway
mlf04630
JAK-STAT signaling pathway
mlf04658
Th1 and Th2 cell differentiation
mlf04659
Th17 cell differentiation
mlf05145
Toxoplasmosis
mlf05160
Hepatitis C
mlf05161
Hepatitis B
mlf05162
Measles
mlf05164
Influenza A
mlf05165
Human papillomavirus infection
mlf05167
Kaposi sarcoma-associated herpesvirus infection
mlf05168
Herpes simplex virus 1 infection
mlf05169
Epstein-Barr virus infection
mlf05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102433832 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
102433832 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
102433832 (TYK2)
04621 NOD-like receptor signaling pathway
102433832 (TYK2)
04658 Th1 and Th2 cell differentiation
102433832 (TYK2)
04659 Th17 cell differentiation
102433832 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
102433832 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
102433832 (TYK2)
05160 Hepatitis C
102433832 (TYK2)
05171 Coronavirus disease - COVID-19
102433832 (TYK2)
05164 Influenza A
102433832 (TYK2)
05162 Measles
102433832 (TYK2)
05168 Herpes simplex virus 1 infection
102433832 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
102433832 (TYK2)
05169 Epstein-Barr virus infection
102433832 (TYK2)
05165 Human papillomavirus infection
102433832 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102433832 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlf01001
]
102433832 (TYK2)
Enzymes [BR:
mlf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102433832 (TYK2)
Protein kinases [BR:
mlf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102433832 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
FERM_C_FAK1
ABC1
APH
RIO1
Motif
Other DBs
NCBI-GeneID:
102433832
NCBI-ProteinID:
XP_014301915
Ensembl:
ENSMLUG00000012345
LinkDB
All DBs
Position
Unknown
AA seq
1188 aa
AA seq
DB search
MPLCHGGATAGGSKPDGDETQLTAITGGLKVFLHWAGPGNREPWVTFSEATLTAEEVCIH
IAHKVGITPPCFNLFALFDAQAQVWLPPNHIFEVSRDTNLTLHFRMRFYFRNWHGTNPQE
PAVYRCRPPGAEASSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
KNESLGMAFLHLCHLALCRGVPLEKVAKKTSFKDCIPRSFRQQIRQYNAFTRLRLRIIFR
RFLHAFQPDSLSQHVVMVKYLATLERLAPRFGTERVPVCHLELLAQAEGEPCYIQDSAQA
PGDPKPKSAVEPPTHEVLVTGTGGIQWRPIQAEVLGFQGPGGGDGGSSRNPHAGLSGKKA
KAQQRGGQPVDRPREAPWAYFCDFRDITHVVLRERHVSIHCQDKRLELTLPSPASALSLV
SLVDGYFRLTADSNHYLCHEVAPPRLVMSIQDGVHGPLLDPFVLAKMQREDGLYLIHWST
SHFNRLILTVAQQDQAPGTPRLRLWKFPIELCEGTFRLQSWDRSFPSVRELRAALQGCSL
RAGDHCFSLRHCCLPQPGEISNLIITRGPQASARSLNLSQLSFHRVCQDDLTQLSHLGQG
TRTNVYEGLLRVGGGGPEEDEAYVGDPTLPGGGHGQELRVVLKVLDTSHHDIALAFYETA
SLMSQVSHVHLTFVHGVCVHGSQNIMVTEYVEHGPLDVWLRRERGRVPVAWKVAVAQQLA
SALSYLEDKRLAHGNVCGRNILLARLGLAEGTSPFIKLSDPGMGLGALSREERVERIPWM
APECLFGGANSLSTAADKWGFGATLLEICFDGEAPLQDRSPAEKEYFYQKQHQLPEPSCP
ELATLTSQCLTYEPAQRPSFRTILRDLTHLQPQNLVEILCVNPTSPASDPTVFHKRYLKK
IRDLGEGHFGKVSLYCYDPTNEGTGEMVAVKALKADCGPQLRTSWRREIDILRTLYHEHI
VKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHRVGLAQLLLFAQQICEGMAYLHTQHY
VHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHDYYRVREDGDSPVFWYAPECLKECKFY
YASDVWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPEK
CPHEIYVLMKNCWEAEASFRPTFQNLIPILKTAHEKYQGQAPSVFSVG
NT seq
3567 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccatgggggggccaccgccgggggcagcaagcccgatggggacgaaact
cagctcacagccatcacaggaggcctgaaggtgttcctgcactgggctggccctggcaac
agggagccctgggtcactttcagcgaggccacactgaccgcagaggaggtctgcattcac
atcgcacacaaagtcggcatcactccaccctgtttcaatctctttgccctctttgatgcc
caggcccaggtctggctgcccccaaaccacatttttgaggtctccagagacacaaacttg
acgctgcacttccgcatgaggttttatttccgcaactggcatggcacaaatcctcaggag
ccagctgtgtaccgctgcaggcccccaggggccgaggcttcgtcagaacaggcagagcag
ggggtgcaactcctggacccagcctcctttgagtacctctttgagcagggcaagcacgag
tttgtgaatgatgtggcatcgctgtgggagctgtcgagtgaggaggagatccaccacttt
aagaacgagagcctgggcatggcctttctgcacctctgtcaccttgctctctgccgcggt
gttcccctggagaaggtggccaagaagaccagcttcaaggactgtatcccgcgctctttc
cggcaacagatccggcagtacaatgcgttcacacggctgcgcctgcggatcatcttccgc
aggttcctgcacgccttccagccggacagcctttcccagcacgtcgtcatggtcaagtac
ctggccacactcgagcggctggcaccccgcttcggcacggagcgtgtgcctgtgtgccac
ctggagctgctagcccaggccgagggggagccctgctatatccaggacagtgcgcaggcc
cctggagatcccaagcccaagtctgcggtcgaaccgcccacccacgaggtgctggtgacc
ggcactggcggcatccagtggcggccaatacaggcagaggtgctgggtttccagggtccc
ggtggtggtgacggtggcagcagcaggaatcctcatgctggcttatctgggaagaaagcc
aaggcccagcagcggggcggccagcccgtggacaggccgcgggaggcgccgtgggcctac
ttctgtgacttccgggacatcacccatgtggtgctgagagaacgccacgtcagcatccac
tgtcaggacaagcgcctggagctgaccctgccgtccccggccagcgccctgtccttggtg
tcactggtggacggctatttccgcctgacggccgactcgaaccactacctgtgccacgag
gtggctcctccacggctggtgatgagcatccaggacggtgtccacgggcccctgctggat
ccatttgtgctggccaagatgcagcgcgaggatggcctctaccttatccactggagcacc
agccacttcaaccgcctcatcctcacggtggcccagcaggaccaggcacctggcacgccg
cgtttgcgcctgtggaagttccccattgagctgtgcgagggcaccttccggctgcagagc
tgggaccggtccttccccagcgtgcgggagctgcgggctgccctgcagggctgctcactg
cgggccggtgaccactgcttctccctgcgccactgctgcctgccgcagcccggagagatc
tccaacctcatcatcacgcgggggcctcaagccagcgccaggtctctcaacctcagccag
ctcagcttccaccgggtctgccaggatgacctcacccagctgtcccacttgggccagggc
acgaggaccaatgtgtatgagggcctcttgcgagttgggggcggaggccctgaggaagac
gaagcatatgttggggaccccaccttgcccggcgggggccatgggcaggagctgcgagtg
gtgctgaaggtgttagacactagtcaccatgacatcgccctggctttctacgagacggcc
agcctcatgagccaggtgtcccacgtgcacctgaccttcgtccacggtgtctgcgtgcac
ggctctcaaaatatcatggtgacagagtacgtggagcatggacccctggacgtgtggctg
cggcgggagaggggccgtgtgcccgtggcctggaaggtggcagtggcccagcagctggcc
agtgccctcagctacctggaggacaagcgcctggctcatggtaacgtgtgtggccggaac
atcctgctggcacgtctagggctggcggagggcaccagcccattcatcaaactgagcgac
cctggcatgggcctgggcgccctctccagggaggagcgggtagagcggatcccctggatg
gcccccgagtgcctgtttggtggggccaacagcctcagcaccgccgctgacaagtggggc
ttcggtgccaccctcctggagatctgcttcgatggggaggcccccctgcaggaccgcagc
cccgccgagaaggagtacttctaccagaagcagcaccagctgcctgaaccctcatgcccg
gagctagccacgctcaccagccagtgcctgacctatgagccggctcagcggccttccttc
cgcaccatccttcgtgacctcactcaccttcagccccaaaatcttgttgaaatcttgtgt
gtgaatccaacctcgccagcatcagaccccacagttttccacaagcgctacttgaagaag
atccgggatctgggtgagggtcacttcggcaaggtcagcctgtactgctatgacccgacc
aacgaaggcaccggcgagatggtggccgtgaaggctctcaaggcggactgcggccctcag
ctccgcaccagctggaggcgggagatcgacatcctgcgcacgctctaccacgagcacatt
gtcaagtacaagggctgctgtgaggaccaaggcgagaaatcggtccagctcgtcatggag
tacgtgcctctgggcagcctccgagactacctgccccggcaccgcgtagggctggcccag
ctgctgctgttcgcccagcagatctgcgagggcatggcctacctgcacacccagcactat
gtccaccgagacctggctgcccgcaacgtgctgctggacaacgacaggctggtcaagatc
ggggactttggcctcgccaaggccgtgcccgaaggccacgactactaccgcgtgcgcgag
gatggggacagccccgtgttctggtacgctcctgagtgtctgaaggagtgtaagttctac
tacgcgtccgatgtctggtcctttggagtcaccatgtatgaactgctgacctactgtgac
tccagccaaagccccccctcgaaattcatcgagctcataggcctcacccaggggcagatg
acggtactgaggctcactgagctgctggaacgaggggagaggctgccacggccagagaaa
tgtccccatgagatatatgtcctcatgaagaactgctgggaggcagaggcctcatttcgc
ccaaccttccagaacctcatacccatcctgaaaacggcccacgagaagtaccagggccag
gccccctcggtgttcagtgtcggctaa
DBGET
integrated database retrieval system
