Myotis lucifugus (little brown bat): 102437135
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Entry
102437135 CDS
T07795
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102437135 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mlf01002
]
102437135 (BACE1)
Enzymes [BR:
mlf01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
102437135 (BACE1)
Peptidases and inhibitors [BR:
mlf01002
]
Aspartic peptidases
Family A1: pepsin family
102437135 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
102437135
NCBI-ProteinID:
XP_006103022
Ensembl:
ENSMLUG00000007898
UniProt:
G1PAB0
LinkDB
All DBs
Position
Unknown
AA seq
500 aa
AA seq
DB search
MAPALPWLLLWMGWAVLPTRCAQPGIRLPLRSGLGGTPLGLRLPRDTEEPDEPGRRGSFV
EMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTY
RDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILG
LAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGTGFSPNQSEVLASVGGSMIIGGID
PSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKV
FEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMSEVTNQSFRITI
LPQQYLRPVEDVATSQDDCYKFAVSQSSTGTVLGAVVMEGFYVVFDRARKRIGFAVSACH
VHDEFRTAAVEGPFVTLDMMDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWR
CLRCLRHQHDDFADDISLLK
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atggccccagcactgccctggctcctgctgtggatgggctgggcagtgctgcccacccgc
tgtgcccagcctggcatccggctgcctctgcggagcgggctagggggcacccccctgggc
ctgcgactgccccgggacaccgaggagcccgacgagcccggccggaggggcagcttcgtg
gagatggtggacaacctgaggggcaagtccggtcagggctactatgtggagatgactgtg
ggcagccccccccagacgctcaacatcctggtggacacgggcagcagcaacttcgcagtg
ggtgccgcgccccaccctttcctgcatcgctactaccagaggcagctgtccagcacatac
cgggacctccgcaagggcgtgtatgtgccctacacccagggcaagtgggagggggagctg
ggcaccgacctggtgagcatcccccatggccccaatgtcactgtacgtgccaacattgcc
gccatcacggagtcagacaagttcttcatcaatggctccaactgggaaggcatcctgggg
ctggcctatgccgagatcgccaggccggacgactccctggagcctttctttgactcgctg
gtaaagcagacccacgtgcccaacctcttctccctgcagctgtgcggcaccggcttctcc
cccaaccagtcggaagtgctggcctcagttggagggagcatgatcattgggggtatcgac
ccctcgctatacacgggcagcctctggtacacacccatccgacgggagtggtattatgag
gtgatcattgtgcgggtagagatcaatggacaggatctgaaaatggactgcaaggagtac
aactatgataagagcatcgtggacagtggcaccaccaaccttcgtttgcccaagaaagtg
tttgaagctgcagtcaaatccatcaaggcagcctcctcgaccgagaagttcccggacggc
ttttggctgggggagcagctggtgtgctggcaggcaggcaccaccccctggaacatcttc
ccggtcatctcgctctacctgatgagtgaggtcaccaaccagtccttccgcatcaccatt
ctcccacagcaatacctgcggccagtggaggatgtggccacatcccaagacgactgctac
aagttcgccgtctcccagtcgtccacgggcaccgtcctgggagctgtcgtcatggagggc
ttctacgtggtctttgatcgggcgagaaagcggatcggctttgctgtcagcgcttgccat
gtgcacgacgagttcaggacggcggcggtggaaggcccgtttgtcaccctggacatgatg
gactgtggctacaacatcccacagacagacgagtcaaccctcatgaccatagcctacgtc
atggccgccatctgcgccctcttcatgctgccactctgcctcatggtgtgccagtggcgc
tgcctccgctgcctgcgccaccagcacgatgactttgctgatgacatctccctgctgaag
tga
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