Myotis lucifugus (little brown bat): 102437402 Help Entry 102437402         CDS       T07795                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4   KO K10160   toll-like receptor 4 Organism mlf  Myotis lucifugus (little brown bat) Pathway mlf04064   NF-kappa B signaling pathway mlf04066   HIF-1 signaling pathway mlf04145   Phagosome mlf04151   PI3K-Akt signaling pathway mlf04217   Necroptosis mlf04613   Neutrophil extracellular trap formation mlf04620   Toll-like receptor signaling pathway mlf04621   NOD-like receptor signaling pathway mlf04936   Alcoholic liver disease mlf05132   Salmonella infection mlf05133   Pertussis mlf05134   Legionellosis mlf05135   Yersinia infection mlf05140   Leishmaniasis mlf05142   Chagas disease mlf05144   Malaria mlf05145   Toxoplasmosis mlf05146   Amoebiasis mlf05152   Tuberculosis mlf05161   Hepatitis B mlf05162   Measles mlf05164   Influenza A mlf05170   Human immunodeficiency virus 1 infection mlf05171   Coronavirus disease - COVID-19 mlf05205   Proteoglycans in cancer mlf05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mlf05321   Inflammatory bowel disease mlf05323   Rheumatoid arthritis mlf05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mlf00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     102437402 (TLR4)    04066 HIF-1 signaling pathway     102437402 (TLR4)    04151 PI3K-Akt signaling pathway     102437402 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     102437402 (TLR4)   09143 Cell growth and death    04217 Necroptosis     102437402 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     102437402 (TLR4)    04620 Toll-like receptor signaling pathway     102437402 (TLR4)    04621 NOD-like receptor signaling pathway     102437402 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     102437402 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102437402 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102437402 (TLR4)    05161 Hepatitis B     102437402 (TLR4)    05171 Coronavirus disease - COVID-19     102437402 (TLR4)    05164 Influenza A     102437402 (TLR4)    05162 Measles     102437402 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     102437402 (TLR4)    05135 Yersinia infection     102437402 (TLR4)    05133 Pertussis     102437402 (TLR4)    05134 Legionellosis     102437402 (TLR4)    05152 Tuberculosis     102437402 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     102437402 (TLR4)    05144 Malaria     102437402 (TLR4)    05145 Toxoplasmosis     102437402 (TLR4)    05140 Leishmaniasis     102437402 (TLR4)    05142 Chagas disease     102437402 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     102437402 (TLR4)    05321 Inflammatory bowel disease     102437402 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102437402 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102437402 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mlf04131]     102437402 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:mlf04054]     102437402 (TLR4)    04090 CD molecules [BR:mlf04090]     102437402 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:mlf00536]     102437402 (TLR4) Membrane trafficking [BR:mlf04131]  Endocytosis   Phagocytosis    Toll-like receptors     102437402 (TLR4) Pattern recognition receptors [BR:mlf04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    102437402 (TLR4) CD molecules [BR:mlf04090]  Proteins   102437402 (TLR4) Glycosaminoglycan binding proteins [BR:mlf00536]  Hyaluronan   Cell surface receptors    102437402 (TLR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 LRR_5 TIR_2 LRR_9 LRR_Zer-1 LRR_NXF1-5 LRR_EndoS ThsB_TIR LRR_R13L1-DRL21 Motif Other DBs NCBI-GeneID:  102437402 NCBI-ProteinID:  XP_006091147 Ensembl:  ENSMLUG00000007417 LinkDB All DBs Position Unknown AA seq 839 aa AA seqDB search MWPTRLAGMLLPAMAFLSCLRPESWDPCVQVVPNVTYQCMELNLYKIPDNLPTSIKNLDL SFNPLRHLGSHSFSNFSELQVLDLSRCEIQKIEDDAYQGLKHLSILILTGNPIQSLAPGA FSGLPSLQTLVAVETNLASLEDFPIRHLKTLKELNVAHNLIDSFKLPDYFSNLPNLEHLD LSNNKIRNIYHEDLQVLHQMPSFKLSLDLSLNPLDFIQPGAFEKIKLHELTLRSNFDSAE VMKTCIQGLAGLKINRLILGEFKNERTIVNFNKSALEGLCNLTIEEFRIAHFDEFPGDDL GFLNCLPEASTISLMGLYLDELKIFPKGFKWQYLNLSKCIFEHFPTLELTFLKQFVFTAN KGITTFTKVNLPNLEFLDLSKNGLSYKSCCSHRDFGTTQLKHLNLSFNNIIIMTSNFLGL EQLERLDFQHSTLKQASDFSVFLSLKNLLYLDISYTNTKIVFLRIFDGLISLQVLKMAGN SFQDALLPNIFRDLTQLTELDLSQCQLERVSQEAFGSLLRLQVLNMSHNHLLSLDMLPFK NLSLRVLDCSFNRIVAANGQELQHFPSNVTSLNLNQNNFACVCEHMRFLQWVQDHRHILV GAEHMMCEKPLAMQGVPVLSFRNATCQMSKTIISVSVLSVLVVSVAAVLVYKFYFHLMLL AGCKKYGKGESTYDAFVIYSSHDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAAN IIQEGFHKSRKVIVVVSRHFIQSRWCLFEYEIAQTWQFLSSHAGIIFIVLQKVERSLLRQ QVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKPWSPEGTEDAESSQDEATTST NT seq 2520 nt NT seq  +upstreamnt  +downstreamnt atgtggcccacccgcctggctgggatgctgctcccagccatggccttcctctcctgcctg agacccgagagctgggacccttgcgtgcaggtggttcctaatgttacttaccagtgcatg gagctgaatctctacaaaatccctgataacctccctacatcaatcaagaacctggacttg agctttaaccccctgaggcatttaggcagccacagcttctccaacttctcagaactgcag gtgctggatttatccaggtgtgaaattcagaagattgaagatgatgcatatcaaggccta aagcatctctccatcttgatattgacaggaaaccctatccagagtttagccccgggagcc ttttctggactgccaagtttacagacactggtggctgtggagacaaacctagcatcacta gaggacttccccatcagacatctgaaaaccttgaaggagcttaatgtggctcacaatcta attgattccttcaagttaccggactatttttctaacctgcctaacctggagcacttggat ctttccaataacaagatccgcaatatttaccatgaagacttgcaggttttacatcaaatg ccctcattcaaactctccttagacctgtccctcaaccctttagactttattcaaccaggt gcctttgaaaaaattaagctccatgaactgactttgagaagtaattttgatagtgcagag gtcatgaaaacgtgtattcaaggtctggctggtttaaagatcaatcggttgattctggga gaatttaaaaatgaaagaaccatagtaaacttcaacaaatctgccctggagggtctgtgc aatttgaccattgaagaattccggatagcacacttcgatgagtttccaggggatgatctt ggctttttaaattgtttgccagaggcttctacaatatctcttatgggtctgtatttagac gagctaaaaatctttccaaaaggtttcaaatggcaatacttaaatttgtctaaatgtata tttgaacattttcctacattggagcttacctttctcaagcagtttgttttcactgccaac aaaggtattaccacttttactaaagttaatctaccaaaccttgagtttctagatctcagt aaaaatggcttgagttacaagtcttgctgctctcaccgtgattttgggacaacccaactg aaacacttaaatctgagcttcaataatattattatcatgacttcaaacttcttgggctta gagcaactagaacgtctggatttccagcattccactctgaaacaggccagtgatttttca gtattcctctcactcaaaaatctcctttaccttgatatctcttacactaacaccaagatt gtcttcctgcgcatctttgatggcttgatcagcctccaagtcttgaaaatggctggcaat tcttttcaggatgcactccttccaaatatcttcagagatctgactcagttgactgaactg gacctctctcagtgtcaactggaacgggtgtcccaggaggcatttggctcactccttaga ctccaggtgctaaatatgagtcacaaccacctcttgtccttggatatgcttccttttaaa aatctctctctccgggttctagactgtagttttaaccgtatagtggccgccaatgggcag gaactacagcattttccaagcaatgtaacttccttaaacctgaaccagaataactttgct tgtgtttgtgaacacatgcgcttcctgcagtgggtccaggatcacaggcacatcttggtg ggagctgaacacatgatgtgtgagaaacctttagctatgcagggtgtgcctgtgctcagt tttagaaatgccacctgccagatgagcaaaactatcattagtgtgtcagttctctcagta ctcgtggtatctgtagccgcagttctggtctacaagttctatttccacctgatgcttctg gctggctgcaaaaagtatggcaaaggggaaagcacctacgatgcctttgtcatctactcc agccatgatgaggactgggtgaggaatgagttggtgaagaacttggaggagggagtcccc ccctttcagctctgccttcactacagagactttatccctggtgtggccattgctgccaac atcatccaggaaggtttccacaagagccggaaggtcattgtggtggtgtcccggcacttc atccagagccgatggtgcctctttgagtacgagatcgcccagacctggcagttcctgagc agtcacgcaggcatcatcttcatcgtcctgcagaaggtggagaggtccctgctcaggcag caggtggaactgtatcgccttctcagcaggaacacttacctagagtgggaggacagtgtc ctgggccggcacatcttctggcgacgactgagaaaagccttgctggatggtaagccatgg agtccagaaggaacagaggatgcagaaagcagccaggatgaagcaacgacctccacctaa

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