KEGG   Myotis lucifugus (little brown bat): 102437455
Entry
102437455         CDS       T07795                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mlf  Myotis lucifugus (little brown bat)
Pathway
mlf01522  Endocrine resistance
mlf04010  MAPK signaling pathway
mlf04012  ErbB signaling pathway
mlf04014  Ras signaling pathway
mlf04024  cAMP signaling pathway
mlf04068  FoxO signaling pathway
mlf04071  Sphingolipid signaling pathway
mlf04137  Mitophagy - animal
mlf04140  Autophagy - animal
mlf04141  Protein processing in endoplasmic reticulum
mlf04210  Apoptosis
mlf04215  Apoptosis - multiple species
mlf04217  Necroptosis
mlf04310  Wnt signaling pathway
mlf04380  Osteoclast differentiation
mlf04510  Focal adhesion
mlf04530  Tight junction
mlf04620  Toll-like receptor signaling pathway
mlf04621  NOD-like receptor signaling pathway
mlf04622  RIG-I-like receptor signaling pathway
mlf04625  C-type lectin receptor signaling pathway
mlf04657  IL-17 signaling pathway
mlf04658  Th1 and Th2 cell differentiation
mlf04659  Th17 cell differentiation
mlf04660  T cell receptor signaling pathway
mlf04664  Fc epsilon RI signaling pathway
mlf04668  TNF signaling pathway
mlf04722  Neurotrophin signaling pathway
mlf04723  Retrograde endocannabinoid signaling
mlf04728  Dopaminergic synapse
mlf04750  Inflammatory mediator regulation of TRP channels
mlf04910  Insulin signaling pathway
mlf04912  GnRH signaling pathway
mlf04914  Progesterone-mediated oocyte maturation
mlf04917  Prolactin signaling pathway
mlf04920  Adipocytokine signaling pathway
mlf04926  Relaxin signaling pathway
mlf04930  Type II diabetes mellitus
mlf04931  Insulin resistance
mlf04932  Non-alcoholic fatty liver disease
mlf04933  AGE-RAGE signaling pathway in diabetic complications
mlf04935  Growth hormone synthesis, secretion and action
mlf04936  Alcoholic liver disease
mlf05010  Alzheimer disease
mlf05012  Parkinson disease
mlf05016  Huntington disease
mlf05017  Spinocerebellar ataxia
mlf05020  Prion disease
mlf05022  Pathways of neurodegeneration - multiple diseases
mlf05132  Salmonella infection
mlf05133  Pertussis
mlf05135  Yersinia infection
mlf05142  Chagas disease
mlf05145  Toxoplasmosis
mlf05152  Tuberculosis
mlf05161  Hepatitis B
mlf05162  Measles
mlf05166  Human T-cell leukemia virus 1 infection
mlf05167  Kaposi sarcoma-associated herpesvirus infection
mlf05169  Epstein-Barr virus infection
mlf05170  Human immunodeficiency virus 1 infection
mlf05171  Coronavirus disease - COVID-19
mlf05200  Pathways in cancer
mlf05208  Chemical carcinogenesis - reactive oxygen species
mlf05210  Colorectal cancer
mlf05212  Pancreatic cancer
mlf05231  Choline metabolism in cancer
mlf05415  Diabetic cardiomyopathy
mlf05417  Lipid and atherosclerosis
mlf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlf00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102437455 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    102437455 (MAPK10)
   04310 Wnt signaling pathway
    102437455 (MAPK10)
   04668 TNF signaling pathway
    102437455 (MAPK10)
   04068 FoxO signaling pathway
    102437455 (MAPK10)
   04071 Sphingolipid signaling pathway
    102437455 (MAPK10)
   04024 cAMP signaling pathway
    102437455 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102437455 (MAPK10)
   04137 Mitophagy - animal
    102437455 (MAPK10)
  09143 Cell growth and death
   04215 Apoptosis - multiple species
    102437455 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102437455 (MAPK10)
   04660 T cell receptor signaling pathway
    102437455 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    102437455 (MAPK10)
   04659 Th17 cell differentiation
    102437455 (MAPK10)
   04657 IL-17 signaling pathway
    102437455 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    102437455 (MAPK10)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    102437455 (MAPK10)
   04926 Relaxin signaling pathway
    102437455 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    102437455 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    102437455 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    102437455 (MAPK10)
   04722 Neurotrophin signaling pathway
    102437455 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102437455 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102437455 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102437455 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    102437455 (MAPK10)
   05231 Choline metabolism in cancer
    102437455 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102437455 (MAPK10)
   05212 Pancreatic cancer
    102437455 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102437455 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    102437455 (MAPK10)
   05161 Hepatitis B
    102437455 (MAPK10)
   05171 Coronavirus disease - COVID-19
    102437455 (MAPK10)
   05162 Measles
    102437455 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102437455 (MAPK10)
   05169 Epstein-Barr virus infection
    102437455 (MAPK10)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102437455 (MAPK10)
   05133 Pertussis
    102437455 (MAPK10)
   05152 Tuberculosis
    102437455 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102437455 (MAPK10)
   05142 Chagas disease
    102437455 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102437455 (MAPK10)
   05012 Parkinson disease
    102437455 (MAPK10)
   05016 Huntington disease
    102437455 (MAPK10)
   05017 Spinocerebellar ataxia
    102437455 (MAPK10)
   05020 Prion disease
    102437455 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    102437455 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102437455 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    102437455 (MAPK10)
   05415 Diabetic cardiomyopathy
    102437455 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102437455 (MAPK10)
   04936 Alcoholic liver disease
    102437455 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    102437455 (MAPK10)
   04931 Insulin resistance
    102437455 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102437455 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102437455 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlf01001]
    102437455 (MAPK10)
Enzymes [BR:mlf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102437455 (MAPK10)
Protein kinases [BR:mlf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102437455 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 102437455
NCBI-ProteinID: XP_006084643
Ensembl: ENSMLUG00000014822
LinkDB
Position
Unknown
AA seq 460 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSQFYSVEVGDSTFTVLKRY
QNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNII
SLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAG
IIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENV
DIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKY
AGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYD
PAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSS
ESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagccagttctacagcgtggaagtaggagactcaaccttcacagttctcaagcgctac
cagaacctaaagcctattggctctggggctcagggaatagtttgtgctgcatatgatgct
gtccttgacagaaatgtggccattaagaagctcagcagaccctttcagaaccaaacacat
gccaagagagcttaccgggaactggtcctcatgaagtgtgtgaaccataaaaacattatt
agtttactaaatgtcttcacaccccagaaaacgctggaggagttccaagatgtttactta
gtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaattagaccatgaa
cgaatgtcttaccttctataccaaatgttgtgtggcatcaagcaccttcactctgctgga
attattcacagggatttaaaaccaagtaacattgtagtcaagtctgattgtacattgaaa
atcctcgactttggactggccaggaccgcaggcacgagcttcatgatgactccttacgtg
gtgacgcgttattacagagcccctgaggtcatcctgggaatgggctacaaggagaacgtg
gatatatggtctgtgggatgcattatgggagaaatggttcgccacaaaatcctctttcca
ggaagggactatattgaccagtggaacaaagtaattgagcaactaggaacaccatgtccg
gaattcatgaagaaattgcaacccacagtaagaaattatgtggagaatcggcctaagtat
gcaggactcacctttcccaagctctttccagattccctcttcccagcggattctgagcac
aataaactcaaagccagccaagccagggacttgttgtcaaagatgctagtgattgaccca
gccaaaaggatatcagtggacgatgccttacagcatccatacatcaacgtctggtacgac
cctgctgaagtggaggcgcctccacctcagatatatgacaaacagttggatgaaagagaa
cacaccattgaagaatggaaagaacttatctataaagaagtaatgaattcagaagaaaag
actaaaaatggtgtcgtaaaaggacaaccttctccttcaggtgcagcagtgaacagcagt
gagagtctccctccatcctcgtccgtcaacgacatctcctccatgtccaccgaccagacc
ctggcgtccgacactgacagcagcctggaagcctcggcgggacccctgggttgttgcagg
tga

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