KEGG   Myotis lucifugus (little brown bat): 102438357
Entry
102438357         CDS       T07795                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
mlf  Myotis lucifugus (little brown bat)
Pathway
mlf04010  MAPK signaling pathway
mlf04012  ErbB signaling pathway
mlf04620  Toll-like receptor signaling pathway
mlf04664  Fc epsilon RI signaling pathway
mlf04668  TNF signaling pathway
mlf04912  GnRH signaling pathway
mlf04926  Relaxin signaling pathway
mlf04935  Growth hormone synthesis, secretion and action
mlf04936  Alcoholic liver disease
mlf05132  Salmonella infection
mlf05135  Yersinia infection
mlf05142  Chagas disease
mlf05161  Hepatitis B
mlf05166  Human T-cell leukemia virus 1 infection
mlf05167  Kaposi sarcoma-associated herpesvirus infection
mlf05169  Epstein-Barr virus infection
mlf05208  Chemical carcinogenesis - reactive oxygen species
mlf05417  Lipid and atherosclerosis
mlf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102438357 (MAP2K4)
   04012 ErbB signaling pathway
    102438357 (MAP2K4)
   04668 TNF signaling pathway
    102438357 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102438357 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    102438357 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102438357 (MAP2K4)
   04926 Relaxin signaling pathway
    102438357 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    102438357 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    102438357 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102438357 (MAP2K4)
   05161 Hepatitis B
    102438357 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102438357 (MAP2K4)
   05169 Epstein-Barr virus infection
    102438357 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102438357 (MAP2K4)
   05135 Yersinia infection
    102438357 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    102438357 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102438357 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    102438357 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102438357 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlf01001]
    102438357 (MAP2K4)
Enzymes [BR:mlf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     102438357 (MAP2K4)
Protein kinases [BR:mlf01001]
 Serine/threonine kinases: STE group
  STE7 family
   102438357 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal Seadorna_VP7 ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 102438357
NCBI-ProteinID: XP_023599627
LinkDB
Position
Unknown
AA seq 295 aa
MVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREVIHTSFL
LSASSATGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLK
IIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGY
DVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFV
NLCLTKDESKRPKYKELLKHPFILMYEERTVEVASYVCKILDQMPATPSSPMYVD
NT seq 888 nt   +upstreamnt  +downstreamnt
atggtccacaaaccaagtggacaaataatggcagttaaaagaattcggtcaacagtggat
gaaaaagaacaaaagcaacttcttatggatttggatgtagtaatgcggagtagtgattgc
ccatacattgttcagttttatggtgcactcttcagagaggtaatacacacttcctttctg
ctgtcagcatcctcagcaaccggtgactgttggatctgtatggaactcatgtctacctcg
tttgataagttttacaaatatgtatatagtgtattagatgatgttattccagaagaaatt
ttaggcaaaatcactttagcaactgtgaaagcactaaaccacttaaaggaaaacttgaaa
atcattcacagagatatcaaaccttccaatatccttctggacagaagtggaaatattaaa
ctctgtgactttggcatcagcggacagcttgtggactctattgccaagaccagagatgct
gggtgtaggccgtacatggcaccggaaagaatagacccaagtgcatcacgacaaggctat
gatgtccgctctgatgtctggagtttggggatcacgttgtacgagttggccacaggccga
tttccttatccaaagtggaatagtgtatttgatcaactaacgcaagttgtgaaaggagac
cccccgcagctgagtaattcggaggaaagggaattctccccgagtttcatcaattttgtc
aacttgtgccttacaaaggacgaatccaaaaggccaaagtataaagaacttctgaaacat
ccctttattttaatgtatgaagaacgtactgtagaggtcgcaagctatgtttgtaaaatc
ctggatcaaatgccagcaactcccagctctcccatgtatgtcgattga

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