KEGG   Myotis lucifugus (little brown bat): 102438914
Entry
102438914         CDS       T07795                                 
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mlf  Myotis lucifugus (little brown bat)
Pathway
mlf01522  Endocrine resistance
mlf04010  MAPK signaling pathway
mlf04015  Rap1 signaling pathway
mlf04068  FoxO signaling pathway
mlf04071  Sphingolipid signaling pathway
mlf04114  Oocyte meiosis
mlf04148  Efferocytosis
mlf04218  Cellular senescence
mlf04261  Adrenergic signaling in cardiomyocytes
mlf04370  VEGF signaling pathway
mlf04380  Osteoclast differentiation
mlf04517  IgSF CAM signaling
mlf04550  Signaling pathways regulating pluripotency of stem cells
mlf04611  Platelet activation
mlf04613  Neutrophil extracellular trap formation
mlf04620  Toll-like receptor signaling pathway
mlf04621  NOD-like receptor signaling pathway
mlf04622  RIG-I-like receptor signaling pathway
mlf04625  C-type lectin receptor signaling pathway
mlf04657  IL-17 signaling pathway
mlf04658  Th1 and Th2 cell differentiation
mlf04659  Th17 cell differentiation
mlf04660  T cell receptor signaling pathway
mlf04664  Fc epsilon RI signaling pathway
mlf04668  TNF signaling pathway
mlf04670  Leukocyte transendothelial migration
mlf04714  Thermogenesis
mlf04722  Neurotrophin signaling pathway
mlf04723  Retrograde endocannabinoid signaling
mlf04728  Dopaminergic synapse
mlf04750  Inflammatory mediator regulation of TRP channels
mlf04912  GnRH signaling pathway
mlf04914  Progesterone-mediated oocyte maturation
mlf04917  Prolactin signaling pathway
mlf04926  Relaxin signaling pathway
mlf04932  Non-alcoholic fatty liver disease
mlf04933  AGE-RAGE signaling pathway in diabetic complications
mlf04935  Growth hormone synthesis, secretion and action
mlf04936  Alcoholic liver disease
mlf05014  Amyotrophic lateral sclerosis
mlf05020  Prion disease
mlf05022  Pathways of neurodegeneration - multiple diseases
mlf05132  Salmonella infection
mlf05133  Pertussis
mlf05135  Yersinia infection
mlf05140  Leishmaniasis
mlf05142  Chagas disease
mlf05145  Toxoplasmosis
mlf05152  Tuberculosis
mlf05161  Hepatitis B
mlf05163  Human cytomegalovirus infection
mlf05167  Kaposi sarcoma-associated herpesvirus infection
mlf05169  Epstein-Barr virus infection
mlf05170  Human immunodeficiency virus 1 infection
mlf05171  Coronavirus disease - COVID-19
mlf05205  Proteoglycans in cancer
mlf05208  Chemical carcinogenesis - reactive oxygen species
mlf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlf05415  Diabetic cardiomyopathy
mlf05417  Lipid and atherosclerosis
mlf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102438914
   04015 Rap1 signaling pathway
    102438914
   04370 VEGF signaling pathway
    102438914
   04668 TNF signaling pathway
    102438914
   04068 FoxO signaling pathway
    102438914
   04071 Sphingolipid signaling pathway
    102438914
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    102438914
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102438914
  09143 Cell growth and death
   04114 Oocyte meiosis
    102438914
   04218 Cellular senescence
    102438914
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102438914
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102438914
   04613 Neutrophil extracellular trap formation
    102438914
   04620 Toll-like receptor signaling pathway
    102438914
   04621 NOD-like receptor signaling pathway
    102438914
   04622 RIG-I-like receptor signaling pathway
    102438914
   04625 C-type lectin receptor signaling pathway
    102438914
   04660 T cell receptor signaling pathway
    102438914
   04658 Th1 and Th2 cell differentiation
    102438914
   04659 Th17 cell differentiation
    102438914
   04657 IL-17 signaling pathway
    102438914
   04664 Fc epsilon RI signaling pathway
    102438914
   04670 Leukocyte transendothelial migration
    102438914
  09152 Endocrine system
   04912 GnRH signaling pathway
    102438914
   04914 Progesterone-mediated oocyte maturation
    102438914
   04917 Prolactin signaling pathway
    102438914
   04926 Relaxin signaling pathway
    102438914
   04935 Growth hormone synthesis, secretion and action
    102438914
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102438914
  09156 Nervous system
   04728 Dopaminergic synapse
    102438914
   04723 Retrograde endocannabinoid signaling
    102438914
   04722 Neurotrophin signaling pathway
    102438914
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102438914
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102438914
  09159 Environmental adaptation
   04714 Thermogenesis
    102438914
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102438914
   05208 Chemical carcinogenesis - reactive oxygen species
    102438914
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102438914
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102438914
   05161 Hepatitis B
    102438914
   05171 Coronavirus disease - COVID-19
    102438914
   05163 Human cytomegalovirus infection
    102438914
   05167 Kaposi sarcoma-associated herpesvirus infection
    102438914
   05169 Epstein-Barr virus infection
    102438914
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102438914
   05135 Yersinia infection
    102438914
   05133 Pertussis
    102438914
   05152 Tuberculosis
    102438914
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102438914
   05140 Leishmaniasis
    102438914
   05142 Chagas disease
    102438914
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102438914
   05020 Prion disease
    102438914
   05022 Pathways of neurodegeneration - multiple diseases
    102438914
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102438914
   05418 Fluid shear stress and atherosclerosis
    102438914
   05415 Diabetic cardiomyopathy
    102438914
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102438914
   04932 Non-alcoholic fatty liver disease
    102438914
   04933 AGE-RAGE signaling pathway in diabetic complications
    102438914
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102438914
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlf01001]
    102438914
Enzymes [BR:mlf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102438914
Protein kinases [BR:mlf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102438914
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 102438914
NCBI-ProteinID: XP_023604468
Ensembl: ENSMLUG00000002164
LinkDB
Position
Unknown
AA seq 287 aa
MRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHETLSEDRVQFLVYQMLKG
LKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNW
MHYTQTVDIWSVGCIMAEMITGKTLFKGNDHLDQLKEILKVTGTPPDEFVQRLQSTDAKN
YMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAAEALTHPYFESLHDAEDE
PQAQKYDESFDDVDRTLDEWKRDTYKEVLSFRPPRQLGAKSSKETAL
NT seq 864 nt   +upstreamnt  +downstreamnt
atgcgccatgagaacgtgatcgggctgctggacgtgttcactccagatgagaccctggat
gacttcacagacttttacctggtcatgccgttcatgggcacggacctgggaaaactcatg
aagcacgagacgctgagcgaggaccgcgtccagttcctcgtctaccagatgctgaagggg
ctgaagtacatccacgcggccggcgtcattcacagggacctgaagcccggcaacctggca
gtgaacgaggactgtgagctgaagatcctggacttcggcctggccaggcaggccgacagc
gagatgaccggatacgtagtgacgcggtggtaccgggcgcccgaggtcatcttgaactgg
atgcactacacacagacagtggacatctggtccgtgggctgcatcatggcggagatgatc
acagggaagacgctgttcaagggcaacgaccacctggaccagctgaaggagatcttgaag
gtgacgggcacgccgcccgacgagttcgtccagaggctgcagagcacggatgcgaagaac
tacatgaagggcctccccgagttggagaagaaggattttgcctccattctgaccaatgca
agccctctggcggtgaacctcctggagaaaatgctggtgctggacgcagagcagcgggtg
acggcggccgaggccctgacccacccgtacttcgagtcgctgcacgacgccgaggatgag
ccccaggcccagaagtacgacgagtcctttgacgacgtggaccgcaccctggacgagtgg
aagcgtgacacgtataaagaggtgctcagcttcaggcccccccggcagctgggggccaag
tcctccaaggagacggccctgtga

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