Myotis lucifugus (little brown bat): 102439190
Help
Entry
102439190 CDS
T07795
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
102439190 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
mlf03021
]
102439190 (SETX)
Enzymes [BR:
mlf01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
102439190 (SETX)
5.6.2.5 RNA 5'-3' helicase
102439190 (SETX)
Transcription machinery [BR:
mlf03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
102439190 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
UvrD-helicase
AAA_19
AAA_30
AAA_22
ResIII
nSTAND3
AAA_16
Helicase_RecD
UvrD_C_2
ATP-synt_D
Motif
Other DBs
NCBI-GeneID:
102439190
NCBI-ProteinID:
XP_006104460
Ensembl:
ENSMLUG00000004836
LinkDB
All DBs
Position
Unknown
AA seq
2707 aa
AA seq
DB search
MSENPHPGISTERLTSLSRYIMSTCCWCTPGGVSAIEFLQHYASRTQSSEFQTANEDLCY
CLECVTEYHKARDKLPLLHEVLWELETLRLINHFEKSMKPEMEDDELYIIENNGEEQPFD
FTGQDFENKLRVPLLEILKYPYLLLHEHVNELCVEALCRMEQANCSFQVFEKQPGIYLFL
VHPNEMVRRWAILTAKGLGKVDRDDYYDLQEVLTCLFKVIELGLLENTDIYTTTVLEKGK
LIILPPHMYDTSNYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMKRQSED
DSEDPFWPALHCFMVILDRLGSKVWGQLIDPIEAFQTIIDNESYNREIQNIRNSSVRAKS
EPESCMDDMVTCSQIVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQD
MRVHNSTFLWFIPFVQSLMDLNDLGMAYIVEVIHHLYSQVKDVLNQTAVVCDKVTEFFFL
ILVSVIELHRSKKCLHLLWVSSQQWVEAIVKCAKLPTTAFARNSEKSSANGSKGAAMITS
LSLHSMPSNSVQFACVQLIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQE
THELQTCLKQIIRNIRLKMPQYTALAELAPPCKTPPASNGKEESEQIGRACEKDIPYLER
CSPTCSKEPVKADVCQVQESSVVSKASNTIEEGNEQNYIKDLKLEDHLSAESHLKQSSKN
LSTERTQDRVKIHTKKQKSVKDNSSCLKQNCTSRNDPEEGCDRGVTMSTHLLTDSNTDSL
EKAPTSKEDFSLKNDVLGKTSKAKTKAQKSDICTELSHVIKKQNRKSAMVKNTVDLEGDL
SISDRKNFCSRTDTAGQKGDGFMQNFSLDPNDNLDHKNEEQKSLNSLLLKQLKNEELDVP
SSHENDCQIQECHVDNKDFISFTSMPKTSPCKDPVTLLGSSDKGINKSTDPVSSDLREQA
PSSPQCDILTDSQIDRDLHTLSLIAQAHVNEFPLDSTQKSSFQLQRKVKDKRSFRANQNN
VRETCEQIIIISDSDEDGDEQTLDSEKHIKQDKMCIEKEWPGQGTSKANMNVDMKLTEEE
KIEEFEDSGSQVFEFESQQKVFSVWQDQKTDHGNSVQEDEKNSCLTHIVDITNDWGYDTD
YAMSEEVTKNEAEGTEHAKPQSDSSVEEVCEIKGKKPKRKQLKKMAKDSLRPSSSVRNED
QSDTLNERDLTENDTKIADIRTSSNSGVERTTLVSLKKSSPKNRTYSKVDRRASVSKTPK
KTHSDTKKGQNKAPNYISCRNTPAIVLPKKFRPCPEPTSKAEKLGLKKAPRRAVVLSQQS
LDVIGQLRNHGKIVGEIGTPKKAKLISPQTLPGNDKKLLVSQDRPFQRQRRPKSHRNRQR
LNGRAYTTRAGPHAAQNSDSVIPDIDRSDDSNKGGTEVMANSSGDQSIKCVSPEQGHGKE
KYVAQVAGDAFLLSPCSSPVLNGRTPTSEITVCTPEDPLGGGNLTGHHLEVPTLKRGQLD
SDSDMEDDIFLTQHDPEDMDLCSQMQNGDNRLIEEVHWKRVHVEDSVNRPQSESLSSTRC
KYKDCVETVKSQGEYCSKHSEAKAADEDVFRKPALPLSASKPLRPSTTKIFSSSSTSRIA
HLSKSLESASASPGLKNKSNGGQPVSKVPQPASPLSPKPRAEVKSLYNIPHSPTPNNSSR
QAFKLPLGERRPFSSPANIFLSSQSISDTFIKEVLKWKYEMFANFDQCGPPTNLCQAISR
SVPVRFQDCEDYFSVFFPLVLLNAFETVAQEWINSPNRGKFYELQLRKFPGEYKKYWEFV
ISLEECELSKQLYPKENDLVFLVPERLKGEKRELEGNSIQASREYHCAYVQKFRRTSVMH
NGKYECSLLIQTQDKFPVNVNETVRCVVISSLVTTQRKLKAMSLLNSRNQLARAILNPNP
MDFCTRNLLTTTSEGINAYLRDFNDDQKKAIETAYAMVKHSPAVAKICLIHGPPGTGKSK
TIVGLLYRLLTERRGQLDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKERCKNKKN
PLGNCGDINLVRVGPERSINNEVLRFSLDNQVNHKMKKEKDLPSYVQEMHRRKEHLDHQL
DELSRQRALSRYGRGIQRQELDEKIAQVSKERQELASKIKEVQGRPQKTQSNIILESHII
CCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQACEVETLTPLIHRCNKLVLVGDPKQL
PPTVISLEPHQRPETRKNLLHVRWAFPLQQAECSCFKTAQDYGYEQSMMARFCKLLEENV
EHHVSGRLPVLQLTVQYRMHPDICLFPSNYIYNKSLKTHKGTESTRCSSSWPFQPYLVFD
VGDGSERRENDSYVNIQEIKLVIELIKLLRDKGRDVNSRSVGVITHYKAQKMKMLKELDK
EFEGRGLAEVDTVDAFQGRQKDCIIVTCVRANATQGSIGFLASLQRLNVAITRAKYSLFI
LGHLRTLMDNQHWNHLIQDAQRRGAIIKTCDKNYKQDAMKILKLKSVVLQRSLTYPPSAA
PEGSSPQGGSPGSDQNRTLLNDSLYHAFLDAKEAADNVAGKDLERPPVKDQLRDPRLLRR
MGRSAEAPGNCLRNPEPRGPQHSEAAPPSGVPGFPVSPQTLDRALKLCMATWSSHRPHVP
CEPPAASIDSTNESDQQGGHNHQREARAVSDRDQEMPSPGNHHLKRSSSWDDGRAEEEDS
GSKKRKL
NT seq
8124 nt
NT seq
+upstream
nt +downstream
nt
atgagtgaaaatcctcacccaggaatctcgactgagaggctcacatctctatccaggtac
ataatgagcacatgttgctggtgtacgccaggtggcgtttccgccattgagttcctacag
cactatgcatccaggacccagtccagtgaattccagacagcaaatgaagacctctgctac
tgcttagagtgtgtgaccgagtaccacaaagcaagggacaaactgccattgttgcatgag
gttttatgggaattagaaaccttacgtctcataaatcactttgaaaaatctatgaaacca
gaaatggaagatgatgaattatatatcatagaaaacaatggagaggaacaaccgtttgac
ttcactggccaagactttgagaataagcttcgagttcctcttctcgaaatcctgaaatac
ccttatctgcttttacatgagcatgttaatgagttatgtgttgaagcactttgtcggatg
gaacaagccaattgctcctttcaggtttttgagaaacagcccggaatctatttgtttttg
gtccatcccaacgaaatggttcgtcgttgggctatcctaactgcaaaaggcttgggaaaa
gtggacagagacgattattatgacttacaagaggttttgacttgcctttttaaagtcatt
gaattggggcttttagaaaatacagacatttatactactactgtccttgagaagggtaaa
ttgatcatcctgcctccacacatgtatgacacttccaactacaaaaactattggttaggg
atttgcatgctgctgaccattctcgaggagcaagccatggattcactgttgttgggctca
gacaaacagaatgatttcatgcagtcaatacttcacaccatgaagaggcagtcagaggat
gatagtgaagatcctttctggccagcattgcactgtttcatggtcattttggatcgcctg
ggatctaaggtctggggtcaacttattgatcctattgaggcctttcagaccattatcgac
aatgaaagctacaacagagagatccagaatatacggaacagctctgtgagggccaagtca
gaaccagagtcgtgtatggatgatatggtgacttgcagccagattgtgtacaattataac
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagccagcgtgcttcagtcagatattggtcaagac
atgcgtgttcacaacagcacatttctgtggttcatcccttttgttcagtccctcatggat
cttaatgatttgggtatggcttacatagtagaggtcatccaccatctgtactcccaagtc
aaagatgttctcaaccaaacagctgtggtgtgtgacaaagtcactgaattttttttccta
attttggtgtcggtgattgaactacatagaagtaaaaaatgtttgcatttgctgtgggtt
agctcccagcagtgggtagaagccattgtgaaatgtgccaagcttcccaccactgcattt
gcacggaattctgagaagtcatctgccaatggctccaaaggagcagcaatgataacgtct
ttgtcactgcattcaatgccatctaactctgtacaattcgcttgtgtgcagctcattaga
agtctccttaaagaaggttatcagcttgggcagcagactctttgtaagcgattctgggat
aagctcaacttattcctgcgaggaaatttatctctaggttggcagttgactagtcaggaa
acccacgagttacaaacttgtttaaagcaaattattagaaacataagattgaaaatgcct
caatatactgctttggcagagctggctcctccatgtaaaacccctcctgcctctaatggt
aaagaagaaagtgaacaaatagggagggcatgtgaaaaagacatcccctatctggaaagg
tgcagcccaacgtgttctaaagaaccagtgaaagctgatgtatgtcaagtacaagagagt
agtgtagtaagcaaagcaagtaacactatagaagaaggtaatgagcaaaattatataaaa
gatttgaaactagaagaccatctctcagctgagtcacacttaaagcagagtagtaaaaac
ctttccactgaaagaactcaagatcgagttaaaatacacacaaagaagcagaagtctgta
aaagataattcctcctgtttgaaacagaactgtacttcaagaaatgatccagaagaggga
tgtgacagaggagtaactatgtcaacacatttgttgactgattctaacactgattctctg
gaaaaggcacccacatcaaaagaggatttctctctaaagaatgatgttcttggcaaaacc
tcaaaagcaaaaactaaggcacagaaaagtgacatttgtactgagttatcccatgtaata
aagaagcaaaacaggaaaagtgccatggtcaaaaatactgtggacttagagggagacctg
tctatctctgaccgtaagaatttctgttcaaggacagatactgcaggtcagaaaggtgat
ggcttcatgcagaacttttctttagaccctaatgataatctggatcataaaaatgaagaa
cagaaatctcttaacagtttattgctgaaacagttgaagaatgaagagttagatgttcct
tcttcccatgaaaacgattgtcaaatacaggaatgtcatgttgataataaagattttatc
tcatttacttccatgcctaaaacatctccctgtaaagatcctgtgactttacttggatca
agtgataaggggattaacaagagcactgatccagtttcttctgacctgagagaacaggcc
cctagcagtcctcagtgtgacatcctaacagattctcagatagacagagaccttcacaca
ttatctttaatagctcaagcccatgtcaatgagtttccattagattcaactcaaaaaagc
tcattccagttacaaagaaaagtaaaagataaaagaagtttcagagccaaccaaaataat
gtcagggaaacctgtgaacaaattattattatttcagattctgatgaagatggtgatgaa
caaactctagattctgagaaacacattaaacaagataaaatgtgcattgagaaagaatgg
ccagggcagggaacttcaaaagctaatatgaatgtggacatgaagctaacagaggaagaa
aagatagaggagtttgaggactctggctctcaggtttttgagtttgaaagccaacagaaa
gtgttttcagtttggcaagatcagaaaacagaccatgggaattcagttcaagaggatgaa
aaaaattcatgtttgactcatatagtagatatcacaaacgattggggttatgatacagat
tacgctatgtctgaagaagttaccaaaaatgaagcagagggcactgagcatgcaaaacca
caaagtgatagttccgttgaggaagtttgtgaaattaaaggaaaaaaacccaagagaaaa
caattaaaaaaaatggctaaagactctttaaggccttcttcttctgtcagaaatgaggac
caatctgatactcttaatgagagggatctaactgaaaatgatactaaaattgcagacata
agaacatcttccaattcaggtgttgagagaaccactctggtctccctgaagaagtcatct
ccaaagaatcgaacttactccaaagtggatcggagagcctcagtttctaaaacgcctaag
aaaacgcattcagataccaaaaaagggcagaataaagctccaaattacataagttgcagg
aacactcctgctattgtgctaccaaagaaatttcgcccgtgtcctgaaccaacttcaaag
gctgagaaacttggtctgaaaaaggctcctcgtcgggcagttgtgttgtctcagcaatct
ttagacgtgataggtcaattacgcaaccatggcaaaattgttggagaaattggtacccca
aaaaaggctaaactaatttctcctcagactctccctgggaacgataagaaactgctcgtg
agtcaagatcgtccatttcagaggcagaggagacccaaatctcatcgaaacagacaaaga
cttaatggcagagcatacactacaagagcaggaccacatgcggcccagaattctgacagt
gtaataccagatatagataggtcagatgacagtaacaaaggaggaactgaggtcatggca
aacagtagtggagatcagtcaataaaatgtgtgtctcctgaacaaggacatgggaaagaa
aaatacgttgctcaggtggctggtgatgcttttcttttgagcccttgtagttcccctgtg
ttaaatggaagaacaccaaccagtgaaattacggtctgtactccagaggaccctttaggt
ggtggcaacctgactggacatcatttagaggtgccaactttgaaaaggggacagcttgac
tccgacagtgatatggaagatgatatctttttaacacaacatgatcccgaagatatggac
ttatgttcacaaatgcagaatggtgataatagactcattgaagaagtccattggaaaaga
gttcatgtagaagattctgtaaatcggcctcagtcagaatctttgagtagcacaagatgt
aagtacaaggattgtgtggaaactgtgaaaagccagggtgagtactgctcaaaacactct
gaagctaaagcagcagatgaagatgtctttcgtaaacctgccctgcctctttctgcctct
aaacctttgagaccttccaccacaaagatttttagctcaagcagtacttcacgaattgct
catctttccaagtctttggaaagtgcctcggcatctccaggcctaaaaaataagtcaaat
ggaggacagcctgtttccaaagtaccacagcctgcctctccgttgtctccaaagccaagg
gctgaagtgaagagtttgtacaatattcctcattctccaactccgaataactccagcagg
caagctttcaaactcccgcttggtgagcgcagacctttttcttctccagccaacattttc
ttgtcatcacagtctatctctgacaccttcatcaaagaggtcttgaaatggaaatatgag
atgtttgcgaactttgaccagtgtgggcccccaacaaatctttgtcaggccatctcaaga
tccgtgcctgtcagatttcaagattgtgaagattacttcagtgttttcttccctctggtg
ttactgaatgcctttgaaacagtagcacaggaatggatcaactctccaaacagaggaaaa
ttctatgagttgcagttacgaaaatttcctggagaatataaaaaatactgggagtttgtg
atttctcttgaggaatgtgaactgtctaaacagctttatccaaaggagaatgacttggtg
tttttggttcctgagagactgaaaggagagaagagagagttggaggggaattccatccaa
gcttctcgtgaatatcactgtgcttatgttcagaaattccgccgcacttcagtcatgcat
aatgggaaatatgagtgttcccttctcatccagactcaggataaattcccagtcaatgta
aatgaaaccgtgagatgtgttgtaatcagttctctggtaactacacaaaggaagttgaaa
gcaatgtctttgttgaatagtcgaaaccaactggccagagctattctgaatccaaacccc
atggacttctgtacaagaaatctactaactacaacatctgagggaattaatgcctactta
agggatttcaacgacgaccagaagaaagcgatagaaaccgcgtacgccatggtgaaacac
tccccggcggtggccaagatctgtctgattcatgggccacctggaacagggaaatcaaaa
accatcgttggcctcctgtaccgcctgctgaccgagaggagggggcagttggatgaaaac
tccaacgccaagatcaagcagaaccgcgtgcttgtgtgtgcgccttccaacgcagccgtg
gatgagctgatgaaaaaaatcatcctcgaattcaaagaaaggtgtaaaaacaagaagaat
cctctgggaaactgtggagatatcaatttagtacgtgtgggtccagaaaggtctattaat
aatgaggtcctaagattcagtttggacaaccaagttaaccacaaaatgaaaaaagaaaaa
gacttaccttcttacgttcaggagatgcatagaagaaaggaacatctagaccatcaacta
gatgaactttcccgccagcgtgctttaagccgatatggaagaggaatccagaggcaagaa
ttagatgaaaaaattgcccaagtttcaaaagaaaggcaggaacttgcgtctaaaattaaa
gaggttcaagggcgcccacagaaaacccagagcaacatcatcctagagtcccacatcatc
tgctgcaccctgagcacgagcggcggtttactgctcgagtccgctttccgggggcaagga
ggagtccccttcagttgtgtcatcgttgacgaggccgggcaggcttgtgaagtggaaacc
cttacccccctcatccaccgctgcaacaagctggtcctcgtgggagacccgaagcagctc
ccccccacagtcatctccttggagccgcatcagagaccagagactagaaagaacctactc
catgtgcgctgggcttttcctttgcaacaggcagagtgcagctgttttaagacggcgcag
gactacggctacgagcagtcgatgatggcccgcttctgcaagctgctggaggagaacgtg
gagcaccacgtgagcggcaggctgccggtgctccagctgaccgtgcagtacaggatgcac
cccgacatctgtctcttcccctccaattacatttacaacaagagcctgaaaacccacaaa
gggactgagagcacgcggtgttcctcaagctggccgtttcagccttacctcgtgtttgac
gtcggggacggctcagaacggcgggaaaatgactcatacgtaaacattcaagaaatcaaa
ctggtgatagaattgattaaacttctcagagacaaaggaagggatgttaattcccgaagc
gttggcgtcatcacccattacaaggctcagaagatgaagatgctgaaggagttggacaaa
gaatttgaaggaagagggctagcagaagtagatactgtggatgcatttcagggtcgtcag
aaagattgtattattgttacatgtgtcagagcaaacgccacacaaggctcaatcggattc
ctggcgagtttgcagaggttgaacgtcgccattacacgagccaagtacagcctcttcatc
cttgggcatctgaggaccctgatggacaatcagcattggaaccacctgattcaagacgcg
cagaggcgtggcgccatcatcaagacctgcgacaagaactataagcaggacgccatgaag
atcctgaagctcaagtcggtggtgctgcagcggagtctgacctaccctccttctgcagcc
cctgagggctccagcccccagggtggctcgccgggcagcgaccagaacaggacattgctg
aatgactccctgtaccacgcattcttggacgctaaggaggctgctgataatgttgctgga
aaggaccttgaacggcctcctgttaaggaccagcttcgggacccacgactgctcaggaga
atgggcagaagtgctgaagccccagggaactgcctaaggaacccagagccccggggcccc
cagcattctgaagcagcgcccccctcaggagtgcccggcttccctgtgagtccccagaca
ctggaccgcgccttgaagctgtgcatggccacatggagcagccacagacctcacgtgccg
tgtgaacctcctgccgccagcattgactccacaaatgaaagtgaccagcaagggggtcac
aaccaccagagagaggccagggctgtcagtgacagggaccaggagatgcccagccctggg
aaccatcacctcaagaggagctccagctgggacgatgggagagccgaggaggaggacagc
ggctcgaagaagaggaagctctag
DBGET
integrated database retrieval system
