Myotis lucifugus (little brown bat): 102441477
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Entry
102441477 CDS
T07795
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X2
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf00260
Glycine, serine and threonine metabolism
mlf00630
Glyoxylate and dicarboxylate metabolism
mlf00670
One carbon pool by folate
mlf01100
Metabolic pathways
mlf01200
Carbon metabolism
mlf01230
Biosynthesis of amino acids
mlf01240
Biosynthesis of cofactors
mlf01523
Antifolate resistance
mlf04981
Folate transport and metabolism
Module
mlf_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
102441477 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
102441477 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102441477 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102441477 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102441477 (SHMT1)
Enzymes [BR:
mlf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
102441477 (SHMT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
DegT_DnrJ_EryC1
DUF6303
Motif
Other DBs
NCBI-GeneID:
102441477
NCBI-ProteinID:
XP_006103916
Ensembl:
ENSMLUG00000000249
UniProt:
G1NSV7
LinkDB
All DBs
Position
Unknown
AA seq
484 aa
AA seq
DB search
MATAVSRAPKDADLWASHDKMLAQPLKDSDIEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFVDELEILCQKRALQVYGLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRRGVRSTDPKTGKEILYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRVYQQQVVANCRALAEALTELGYKIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLETEFRK
VAHFIHKGIELTLQIQKDAGDKASLKEFKEKLAGDERHRGAARALREEVESFASLFPLPG
LPGF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcgactgcggtgagcagggctcccaaggatgctgacctgtgggcctcgcatgacaaa
atgctggcgcagcccctgaaagacagcgacatcgaggtttacaacatcattaagaaggag
agtaaccggcagagggttggactagagctgatcgcctcagagaatttcgccagccgagca
gttttggaggccctgggctcttgcttaaataacaagtactctgaggggtaccctggccag
aggtattacggcgggactgagtttgttgatgagctggagatcctctgtcagaagcgagcg
ctgcaggtctacggtctggacccccagtgctggggggtcaacgtccagccctactcgggc
tcccctgccaacttcgcagtgtacaccgccctggtggaaccccacgggcgcatcatgggc
ctggacctgcccgacggaggccacctgacccacgggttcatgacggacaagaagaaaatc
tctgctacatccatcttttttgaatctatgccctataaggtgaaccccgacactggctac
atcaactacgaccagctggaggaaaacgcccgcctcttccacccgaggctcattatcgca
ggaaccagctgctactcccgaaacctggactacgctcgattgcggaagattgccgatgac
aacggggcgtatctcatggccgacatggcgcacatcagcgggctggtggcggctggcgtg
gtgccctcccccttcgaacactgccacgtggtgtccaccaccacccacaagacccttcga
ggctgccgcgcgggcatgatcttctacaggcgaggagtgcgcagcacggaccccaaaacc
ggcaaagagatcctgtacaacctggagtcgctcatcaactctgctgtgttcccagggctg
cagggagggccccacaaccacgccattgctggggtggccgtggctctgaagcaggccatg
actccagagttccgggtgtaccagcagcaggtggtggccaactgcagggcgctggctgag
gccctgacggagctgggctacaaaatagtaacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacagatggtggccgggctgagaaggtgctagaagcctgt
tctattgcttgcaacaagaacacctgcccaggtgacagaagcgccctgcggcccagtggg
ctgcgactggggaccccagcactgacatcccgaggacttctggaaacagagttccggaaa
gtagcccactttattcacaaagggatagaactgactctgcagatccagaaggacgctggg
gacaaggccagcctgaaggagttcaaggagaagctagcaggggatgagcggcaccgtggg
gccgcccgagccctccgggaggaggtggagagcttcgcgtctctcttccctctgcccggc
ctgccgggcttttag
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