Mustela lutreola (European mink): 131811758
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Entry
131811758 CDS
T09578
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk01521
EGFR tyrosine kinase inhibitor resistance
mlk01522
Endocrine resistance
mlk01524
Platinum drug resistance
mlk04010
MAPK signaling pathway
mlk04012
ErbB signaling pathway
mlk04014
Ras signaling pathway
mlk04015
Rap1 signaling pathway
mlk04022
cGMP-PKG signaling pathway
mlk04024
cAMP signaling pathway
mlk04062
Chemokine signaling pathway
mlk04066
HIF-1 signaling pathway
mlk04068
FoxO signaling pathway
mlk04071
Sphingolipid signaling pathway
mlk04072
Phospholipase D signaling pathway
mlk04114
Oocyte meiosis
mlk04140
Autophagy - animal
mlk04148
Efferocytosis
mlk04150
mTOR signaling pathway
mlk04151
PI3K-Akt signaling pathway
mlk04210
Apoptosis
mlk04218
Cellular senescence
mlk04261
Adrenergic signaling in cardiomyocytes
mlk04270
Vascular smooth muscle contraction
mlk04350
TGF-beta signaling pathway
mlk04360
Axon guidance
mlk04370
VEGF signaling pathway
mlk04371
Apelin signaling pathway
mlk04380
Osteoclast differentiation
mlk04510
Focal adhesion
mlk04520
Adherens junction
mlk04540
Gap junction
mlk04550
Signaling pathways regulating pluripotency of stem cells
mlk04611
Platelet activation
mlk04613
Neutrophil extracellular trap formation
mlk04620
Toll-like receptor signaling pathway
mlk04621
NOD-like receptor signaling pathway
mlk04625
C-type lectin receptor signaling pathway
mlk04650
Natural killer cell mediated cytotoxicity
mlk04657
IL-17 signaling pathway
mlk04658
Th1 and Th2 cell differentiation
mlk04659
Th17 cell differentiation
mlk04660
T cell receptor signaling pathway
mlk04662
B cell receptor signaling pathway
mlk04664
Fc epsilon RI signaling pathway
mlk04666
Fc gamma R-mediated phagocytosis
mlk04668
TNF signaling pathway
mlk04713
Circadian entrainment
mlk04720
Long-term potentiation
mlk04722
Neurotrophin signaling pathway
mlk04723
Retrograde endocannabinoid signaling
mlk04724
Glutamatergic synapse
mlk04725
Cholinergic synapse
mlk04726
Serotonergic synapse
mlk04730
Long-term depression
mlk04810
Regulation of actin cytoskeleton
mlk04910
Insulin signaling pathway
mlk04912
GnRH signaling pathway
mlk04914
Progesterone-mediated oocyte maturation
mlk04915
Estrogen signaling pathway
mlk04916
Melanogenesis
mlk04917
Prolactin signaling pathway
mlk04919
Thyroid hormone signaling pathway
mlk04921
Oxytocin signaling pathway
mlk04926
Relaxin signaling pathway
mlk04928
Parathyroid hormone synthesis, secretion and action
mlk04929
GnRH secretion
mlk04930
Type II diabetes mellitus
mlk04933
AGE-RAGE signaling pathway in diabetic complications
mlk04934
Cushing syndrome
mlk04935
Growth hormone synthesis, secretion and action
mlk04960
Aldosterone-regulated sodium reabsorption
mlk05010
Alzheimer disease
mlk05020
Prion disease
mlk05022
Pathways of neurodegeneration - multiple diseases
mlk05034
Alcoholism
mlk05132
Salmonella infection
mlk05133
Pertussis
mlk05135
Yersinia infection
mlk05140
Leishmaniasis
mlk05142
Chagas disease
mlk05145
Toxoplasmosis
mlk05152
Tuberculosis
mlk05160
Hepatitis C
mlk05161
Hepatitis B
mlk05163
Human cytomegalovirus infection
mlk05164
Influenza A
mlk05165
Human papillomavirus infection
mlk05166
Human T-cell leukemia virus 1 infection
mlk05167
Kaposi sarcoma-associated herpesvirus infection
mlk05170
Human immunodeficiency virus 1 infection
mlk05171
Coronavirus disease - COVID-19
mlk05200
Pathways in cancer
mlk05203
Viral carcinogenesis
mlk05205
Proteoglycans in cancer
mlk05206
MicroRNAs in cancer
mlk05207
Chemical carcinogenesis - receptor activation
mlk05208
Chemical carcinogenesis - reactive oxygen species
mlk05210
Colorectal cancer
mlk05211
Renal cell carcinoma
mlk05212
Pancreatic cancer
mlk05213
Endometrial cancer
mlk05214
Glioma
mlk05215
Prostate cancer
mlk05216
Thyroid cancer
mlk05218
Melanoma
mlk05219
Bladder cancer
mlk05220
Chronic myeloid leukemia
mlk05221
Acute myeloid leukemia
mlk05223
Non-small cell lung cancer
mlk05224
Breast cancer
mlk05225
Hepatocellular carcinoma
mlk05226
Gastric cancer
mlk05230
Central carbon metabolism in cancer
mlk05231
Choline metabolism in cancer
mlk05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mlk05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
131811758 (MAPK1)
04012 ErbB signaling pathway
131811758 (MAPK1)
04014 Ras signaling pathway
131811758 (MAPK1)
04015 Rap1 signaling pathway
131811758 (MAPK1)
04350 TGF-beta signaling pathway
131811758 (MAPK1)
04370 VEGF signaling pathway
131811758 (MAPK1)
04371 Apelin signaling pathway
131811758 (MAPK1)
04668 TNF signaling pathway
131811758 (MAPK1)
04066 HIF-1 signaling pathway
131811758 (MAPK1)
04068 FoxO signaling pathway
131811758 (MAPK1)
04072 Phospholipase D signaling pathway
131811758 (MAPK1)
04071 Sphingolipid signaling pathway
131811758 (MAPK1)
04024 cAMP signaling pathway
131811758 (MAPK1)
04022 cGMP-PKG signaling pathway
131811758 (MAPK1)
04151 PI3K-Akt signaling pathway
131811758 (MAPK1)
04150 mTOR signaling pathway
131811758 (MAPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
131811758 (MAPK1)
04148 Efferocytosis
131811758 (MAPK1)
09143 Cell growth and death
04114 Oocyte meiosis
131811758 (MAPK1)
04210 Apoptosis
131811758 (MAPK1)
04218 Cellular senescence
131811758 (MAPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
131811758 (MAPK1)
04520 Adherens junction
131811758 (MAPK1)
04540 Gap junction
131811758 (MAPK1)
04550 Signaling pathways regulating pluripotency of stem cells
131811758 (MAPK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
131811758 (MAPK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
131811758 (MAPK1)
04613 Neutrophil extracellular trap formation
131811758 (MAPK1)
04620 Toll-like receptor signaling pathway
131811758 (MAPK1)
04621 NOD-like receptor signaling pathway
131811758 (MAPK1)
04625 C-type lectin receptor signaling pathway
131811758 (MAPK1)
04650 Natural killer cell mediated cytotoxicity
131811758 (MAPK1)
04660 T cell receptor signaling pathway
131811758 (MAPK1)
04658 Th1 and Th2 cell differentiation
131811758 (MAPK1)
04659 Th17 cell differentiation
131811758 (MAPK1)
04657 IL-17 signaling pathway
131811758 (MAPK1)
04662 B cell receptor signaling pathway
131811758 (MAPK1)
04664 Fc epsilon RI signaling pathway
131811758 (MAPK1)
04666 Fc gamma R-mediated phagocytosis
131811758 (MAPK1)
04062 Chemokine signaling pathway
131811758 (MAPK1)
09152 Endocrine system
04910 Insulin signaling pathway
131811758 (MAPK1)
04929 GnRH secretion
131811758 (MAPK1)
04912 GnRH signaling pathway
131811758 (MAPK1)
04915 Estrogen signaling pathway
131811758 (MAPK1)
04914 Progesterone-mediated oocyte maturation
131811758 (MAPK1)
04917 Prolactin signaling pathway
131811758 (MAPK1)
04921 Oxytocin signaling pathway
131811758 (MAPK1)
04926 Relaxin signaling pathway
131811758 (MAPK1)
04935 Growth hormone synthesis, secretion and action
131811758 (MAPK1)
04919 Thyroid hormone signaling pathway
131811758 (MAPK1)
04928 Parathyroid hormone synthesis, secretion and action
131811758 (MAPK1)
04916 Melanogenesis
131811758 (MAPK1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
131811758 (MAPK1)
04270 Vascular smooth muscle contraction
131811758 (MAPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
131811758 (MAPK1)
09156 Nervous system
04724 Glutamatergic synapse
131811758 (MAPK1)
04725 Cholinergic synapse
131811758 (MAPK1)
04726 Serotonergic synapse
131811758 (MAPK1)
04720 Long-term potentiation
131811758 (MAPK1)
04730 Long-term depression
131811758 (MAPK1)
04723 Retrograde endocannabinoid signaling
131811758 (MAPK1)
04722 Neurotrophin signaling pathway
131811758 (MAPK1)
09158 Development and regeneration
04360 Axon guidance
131811758 (MAPK1)
04380 Osteoclast differentiation
131811758 (MAPK1)
09159 Environmental adaptation
04713 Circadian entrainment
131811758 (MAPK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
131811758 (MAPK1)
05206 MicroRNAs in cancer
131811758 (MAPK1)
05205 Proteoglycans in cancer
131811758 (MAPK1)
05207 Chemical carcinogenesis - receptor activation
131811758 (MAPK1)
05208 Chemical carcinogenesis - reactive oxygen species
131811758 (MAPK1)
05203 Viral carcinogenesis
131811758 (MAPK1)
05230 Central carbon metabolism in cancer
131811758 (MAPK1)
05231 Choline metabolism in cancer
131811758 (MAPK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
131811758 (MAPK1)
09162 Cancer: specific types
05210 Colorectal cancer
131811758 (MAPK1)
05212 Pancreatic cancer
131811758 (MAPK1)
05225 Hepatocellular carcinoma
131811758 (MAPK1)
05226 Gastric cancer
131811758 (MAPK1)
05214 Glioma
131811758 (MAPK1)
05216 Thyroid cancer
131811758 (MAPK1)
05221 Acute myeloid leukemia
131811758 (MAPK1)
05220 Chronic myeloid leukemia
131811758 (MAPK1)
05218 Melanoma
131811758 (MAPK1)
05211 Renal cell carcinoma
131811758 (MAPK1)
05219 Bladder cancer
131811758 (MAPK1)
05215 Prostate cancer
131811758 (MAPK1)
05213 Endometrial cancer
131811758 (MAPK1)
05224 Breast cancer
131811758 (MAPK1)
05223 Non-small cell lung cancer
131811758 (MAPK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
131811758 (MAPK1)
05170 Human immunodeficiency virus 1 infection
131811758 (MAPK1)
05161 Hepatitis B
131811758 (MAPK1)
05160 Hepatitis C
131811758 (MAPK1)
05171 Coronavirus disease - COVID-19
131811758 (MAPK1)
05164 Influenza A
131811758 (MAPK1)
05163 Human cytomegalovirus infection
131811758 (MAPK1)
05167 Kaposi sarcoma-associated herpesvirus infection
131811758 (MAPK1)
05165 Human papillomavirus infection
131811758 (MAPK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
131811758 (MAPK1)
05135 Yersinia infection
131811758 (MAPK1)
05133 Pertussis
131811758 (MAPK1)
05152 Tuberculosis
131811758 (MAPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
131811758 (MAPK1)
05140 Leishmaniasis
131811758 (MAPK1)
05142 Chagas disease
131811758 (MAPK1)
09164 Neurodegenerative disease
05010 Alzheimer disease
131811758 (MAPK1)
05020 Prion disease
131811758 (MAPK1)
05022 Pathways of neurodegeneration - multiple diseases
131811758 (MAPK1)
09165 Substance dependence
05034 Alcoholism
131811758 (MAPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
131811758 (MAPK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
131811758 (MAPK1)
04933 AGE-RAGE signaling pathway in diabetic complications
131811758 (MAPK1)
04934 Cushing syndrome
131811758 (MAPK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
131811758 (MAPK1)
01524 Platinum drug resistance
131811758 (MAPK1)
01522 Endocrine resistance
131811758 (MAPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlk01001
]
131811758 (MAPK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mlk03036
]
131811758 (MAPK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mlk04147
]
131811758 (MAPK1)
Enzymes [BR:
mlk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
131811758 (MAPK1)
Protein kinases [BR:
mlk01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
131811758 (MAPK1)
Chromosome and associated proteins [BR:
mlk03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
131811758 (MAPK1)
Exosome [BR:
mlk04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
131811758 (MAPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Choline_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
131811758
NCBI-ProteinID:
XP_058996529
LinkDB
All DBs
Position
11:complement(64133226..64241465)
Genome browser
AA seq
360 aa
AA seq
DB search
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgat
gtggggccgcgctacaccaacctctcgtacatcggcgagggcgcctacggcatggtgtgc
tctgcttatgataatgtcaacaaagttcgagtagctatcaagaaaatcagtccttttgaa
caccaaacctactgccagagaaccctgagggagataaaaatcttactgcgcttcagacat
gagaacatcattggaatcaatgacattattcgagcaccaaccattgagcaaatgaaagat
gtatatatagtacaggacctcatggaaacagatctctacaagctcttgaagacgcaacac
ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttaaaatatatc
cattcagctaatgtactgcatcgtgacctcaaaccttccaacctgctgctcaacaccacc
tgcgatctcaagatctgtgactttggcttggcccgtgttgcagatccagaccatgatcac
acagggttcctgacggagtatgtagccacacgttggtacagggctccagaaatcatgttg
aattccaagggctataccaagtccattgatatttggtctgtaggctgcattctggcagag
atgctgtccaacaggcccatcttccctgggaagcattatctcgaccagctgaaccacatt
ctgggtattcttggatccccatcacaggaagacctgaactgtataataaatttaaaagct
agaaactacttgctttctcttccacacaaaaataaggtgccatggaacaggctgttccca
aatgctgattccaaagctctggatttactggacaaaatgttgacattcaaccctcacaag
aggattgaagtagaacaggctctggcccatccgtatctggagcagtattatgacccaagc
gatgagcccattgccgaggcgccattcaagtttgacatggagctggacgacctgcccaag
gaaaagctcaaagagctcatcttcgaagagacagctagattccagccgggatacagatct
taa
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