Mustela lutreola (European mink): 131815770
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Entry
131815770 CDS
T09578
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk01521
EGFR tyrosine kinase inhibitor resistance
mlk01522
Endocrine resistance
mlk01524
Platinum drug resistance
mlk04010
MAPK signaling pathway
mlk04012
ErbB signaling pathway
mlk04020
Calcium signaling pathway
mlk04066
HIF-1 signaling pathway
mlk04151
PI3K-Akt signaling pathway
mlk04510
Focal adhesion
mlk04520
Adherens junction
mlk04530
Tight junction
mlk05200
Pathways in cancer
mlk05205
Proteoglycans in cancer
mlk05206
MicroRNAs in cancer
mlk05212
Pancreatic cancer
mlk05213
Endometrial cancer
mlk05215
Prostate cancer
mlk05219
Bladder cancer
mlk05223
Non-small cell lung cancer
mlk05224
Breast cancer
mlk05226
Gastric cancer
mlk05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
131815770 (ERBB2)
04012 ErbB signaling pathway
131815770 (ERBB2)
04066 HIF-1 signaling pathway
131815770 (ERBB2)
04020 Calcium signaling pathway
131815770 (ERBB2)
04151 PI3K-Akt signaling pathway
131815770 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
131815770 (ERBB2)
04520 Adherens junction
131815770 (ERBB2)
04530 Tight junction
131815770 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
131815770 (ERBB2)
05206 MicroRNAs in cancer
131815770 (ERBB2)
05205 Proteoglycans in cancer
131815770 (ERBB2)
05230 Central carbon metabolism in cancer
131815770 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
131815770 (ERBB2)
05226 Gastric cancer
131815770 (ERBB2)
05219 Bladder cancer
131815770 (ERBB2)
05215 Prostate cancer
131815770 (ERBB2)
05213 Endometrial cancer
131815770 (ERBB2)
05224 Breast cancer
131815770 (ERBB2)
05223 Non-small cell lung cancer
131815770 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
131815770 (ERBB2)
01524 Platinum drug resistance
131815770 (ERBB2)
01522 Endocrine resistance
131815770 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlk01001
]
131815770 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mlk04147
]
131815770 (ERBB2)
04090 CD molecules [BR:
mlk04090
]
131815770 (ERBB2)
Enzymes [BR:
mlk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
131815770 (ERBB2)
Protein kinases [BR:
mlk01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
131815770 (ERBB2)
Exosome [BR:
mlk04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
131815770 (ERBB2)
CD molecules [BR:
mlk04090
]
Proteins
131815770 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Bestrophin-like
Kinase-like
CcmD
Motif
Other DBs
NCBI-GeneID:
131815770
NCBI-ProteinID:
XP_059003690
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All DBs
Position
15:complement(22128600..22153071)
Genome browser
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGAVGTQVCTGTDMKLRLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDHYALAVLDNG
DPPEGGPSVAGAAPGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LTLIDTNRSRACQPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTSCP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFERDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLRGLGISSLGLRSLRELGSGLVLIHRNAHLCFIHTV
PWDQLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHSECRPQNGSVTCFGSEADQCVACAHYKDTPFCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDERGCPAEQRASPVTSIIAAVVG
ILLAVLVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGPAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPRAPSEG
AGSDVFDGDLGMGAAKGLQSLPLQDTSPLQRYSEDPTAPLPPETDGYVAPLTCSPQPEYV
NQPEVWPQPPSPLEGPLPPPRPAGATLERPKTLSPKTLSPGKNGVAKDVFAFGSAVENPE
YLVPRGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctgctcgccctcctgccctccggagcc
gtgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggatatgctccgccacctctaccaggcctgtcaagtggtgcagggtaacctg
gagctcacctatctgcctgccaatgccagcctgtccttcctgcaggatatccaggaggtg
cagggctacgtgctcatcgctcacagccaagtgaggcaggtcccgctgcagaggctccga
attgtacggggcacccagctctttgaggaccactatgccctggccgtgctggacaatgga
gatccgcccgaggggggcccctctgtggcaggggctgccccaggagggctgcgggagcta
cagcttcgaagcctcacagagatcctgaagggcggggtcttgattcagcggaacccacag
ctctgccaccaggacacgatcctgtggaaggacatcttccacaagaacaaccagctggcc
ctcacgctaatagacaccaaccgctctcgggcctgccagccctgttctccagcttgtaaa
gacccccactgctggggagcaagttccggggactgtcagagcttgacgcgaaccgtctgt
gctggcggctgtgcccgctgcaagggcccgaaacccacggactgctgccacgagcagtgt
gcggctggctgcacgggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctacactgtccagccctggtcacctacaacacagacacctttgaa
tccatgcccaaccctgagggccggtacacctttggagccagctgtgtgacctcctgtccc
tacaattacctgtcaacggatgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacggctgaggatggaacgcagcgttgtgagaaatgcagcaagccctgtgcccga
gtgtgctacggcctgggcatggagcacctgcgggaggtgagggcggtcaccagcgccaac
atccaagagtttgccggctgcaagaagatctttgggagcctggcatttctaccagagagc
tttgagagagacccagcctccaacactgcccccctccagcctgagcagctcagagtgttt
gaggccttggaggagatcacaggttacctgtacatctcagcatggccagacagcctgcct
gacctcagtgtcttccagaaccttcgagtcatccggggacgagttctgcatgacggtgcc
tactcgctgaccctgcgagggctgggcatcagctctctggggctgcgctcgctgcgggaa
ctgggcagcgggctggtcctcatccaccgcaacgcccacctgtgcttcatacacacggtg
ccctgggaccagctcttccggaacccgcaccaggccctgctccacagcgccaaccggcca
gaggccgagtgtgtgggcgagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggctaccccgggagtatgtgaaggacaggtactgt
ctcccatgccactccgagtgtcggccgcagaatggctcagtgacctgctttgggtcggaa
gctgaccagtgtgtggcctgcgcccactacaaagacactcccttttgcgtggctcgctgc
cccagtggtgtgaaacccgacctctccttcatgcccatttggaagttcgccgatgaggag
ggcacgtgccagccatgccccatcaactgcacccactcctgtgcggatctggacgagagg
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgccgctgtggtgggc
attctgctggccgtgcttgtggggctggtcctcggcatcctaatcaagcgaaggcggcag
aagatccgcaagtacacgatgcggaggctgctgcaggaaaccgagctggtggagccgctg
acgcccagcggagccatgcccaaccaggctcagatgcggatcctgaaagagacagaactg
aggaaggtgaaagtgcttggatccggagcctttggcactgtctacaagggcatctggatc
cctgatggggaaaatgtgaagattccagtggccattaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggcgtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcttagaccacgtccgagagcatcgtgggcgcctgggctcccaa
gacctgctgaactggtgtgtgcagatcgccaaggggatgagctacttagaggatgttcgg
ctggtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
ataacagactttgggctggctcggctgctggacattgacgagaccgagtaccacgcagat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagtgacgtgtggagctacggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggaaaagggggaacgg
ctgccccagccccccatctgcaccattgacgtctacatgatcatggtcaaatgttggatg
atagactctgaatgtcgaccacggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgcttcgtggtcatccagaatgaagacttgggccctgccagcccactg
gacagcaccttctaccgctcgctgctggaagatgatgacatgggggacctcgtggatgct
gaggagtacctggtgccccagcaggggttcttctgccccgaccctgccccaggtgctggg
ggcccagcccaccgcaggcaccgcagctcatccacgaggagtggcggtggtgagctgaca
ctgggactggagccctccgaggaggagccccccaagtctccacgggcaccctcagagggg
gctggctctgacgtgtttgatggcgacttgggaatgggggcagccaaggggctgcagagc
cttcccctacaggacaccagccctctacagcggtacagcgaagaccctactgcacccctg
cccccagagactgatggctacgttgcccccctgacctgcagcccccagcctgaatacgtg
aaccagccggaggtttggccgcagcccccctcacccctagaaggccctctgccaccgcct
cgacctgccggtgccactctggaaaggcccaagactctgtcccccaagactctctcccct
ggcaagaatggggttgccaaagacgtttttgcctttgggagtgctgtggagaaccctgag
tacttggtaccccggggcagggctgcccctcagccccaccctcctccagccttcagtcca
gcctttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagc
acctttgaagggacccctacagcagagaaccctgagtacctgggcctggatgtgccagtg
tga
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