KEGG   Mustela lutreola (European mink): 131816095
Entry
131816095         CDS       T09578                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
mlk  Mustela lutreola (European mink)
Pathway
mlk04010  MAPK signaling pathway
mlk04015  Rap1 signaling pathway
mlk04218  Cellular senescence
mlk04620  Toll-like receptor signaling pathway
mlk04664  Fc epsilon RI signaling pathway
mlk04668  TNF signaling pathway
mlk04714  Thermogenesis
mlk04750  Inflammatory mediator regulation of TRP channels
mlk04912  GnRH signaling pathway
mlk04935  Growth hormone synthesis, secretion and action
mlk04936  Alcoholic liver disease
mlk05014  Amyotrophic lateral sclerosis
mlk05022  Pathways of neurodegeneration - multiple diseases
mlk05132  Salmonella infection
mlk05135  Yersinia infection
mlk05145  Toxoplasmosis
mlk05161  Hepatitis B
mlk05169  Epstein-Barr virus infection
mlk05170  Human immunodeficiency virus 1 infection
mlk05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlk05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    131816095 (MAP2K3)
   04015 Rap1 signaling pathway
    131816095 (MAP2K3)
   04668 TNF signaling pathway
    131816095 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    131816095 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    131816095 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    131816095 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    131816095 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    131816095 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    131816095 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    131816095 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    131816095 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    131816095 (MAP2K3)
   05161 Hepatitis B
    131816095 (MAP2K3)
   05169 Epstein-Barr virus infection
    131816095 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    131816095 (MAP2K3)
   05135 Yersinia infection
    131816095 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    131816095 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    131816095 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    131816095 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    131816095 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    131816095 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlk01001]
    131816095 (MAP2K3)
Enzymes [BR:mlk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     131816095 (MAP2K3)
Protein kinases [BR:mlk01001]
 Serine/threonine kinases: STE group
  STE7 family
   131816095 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Seadorna_VP7 Pkinase_fungal Choline_kinase APH RIO1 DUF4344
Other DBs
NCBI-GeneID: 131816095
NCBI-ProteinID: XP_059004451
LinkDB
Position
15:49865049..49894335
AA seq 347 aa
MESPASSQPASMPQTKGKAKRKKDLRISCMSKPLVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggaatcgcccgcctccagtcagcccgccagcatgccccagaccaaagggaaggccaaa
aggaagaaggacttacggatatcctgcatgtccaagccgctcgtgcccaaccccacaccc
ccccggaaccttgactcccggaccttcattaccattggagacaggaacttcgaggtggag
gccgatgacctggtgaccatctcggagctgggccgcggagcctatggggtggtggagaag
gtgcggcacgcccagagtggcaccatcatggccgtcaagcggatccgggccaccgtgaac
tcacaggagcagaagcgtctgctcatggacttggacatcaacatgcgcacagtcgactgc
ttctacaccgtcaccttctacggggccctcttcagagagggagatgtgtggatctgcatg
gagctcatggacacatccctggacaagttctaccggaaggtgctcgaaaagaacatgacc
attccagaggacattctgggggaaattgctgtgtctatcgtgagggcactggagcatctg
cacagcaagctgtccgtgatccacagagatgtgaagccgtccaatgtcctcatcaacaag
gagggtcacgtgaagatgtgtgactttgggattagtggctacttggtggattctgtggcc
aagacgctggacgccggctgcaaaccctacatggctcctgagagaatcaatccggagctg
aaccagaagggctacaatgtcaagtccgatgtctggagcctcggcatcaccatgatcgag
atggccatcctccgctttccgtatgaatcctggggaactcctttccagcagctgaagcag
gtggtggaagagccgtctccccagctcccagctgaccgtttctctcccgagtttgtggac
ttcactgcacagtgcttgaggaagaaccctgcggagcgcatgagctacttggagctgatg
gagcacccgttcttcacattgcacaaaaccaagaagacggacattgctgccttcgtgaag
gagatcctgggggaggactcgtag

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