| Entry |
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| Symbol |
PFAS
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| Name |
(RefSeq) phosphoribosylformylglycinamidine synthase
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| KO |
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| Organism |
mlk Mustela lutreola (European mink)
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| Pathway |
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| Module |
| mlk_M00048 | De novo purine biosynthesis, PRPP + glutamine => IMP |
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| Brite |
KEGG Orthology (KO) [BR:mlk00001]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
131816130 (PFAS)
Enzymes [BR:mlk01000]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
131816130 (PFAS)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
15:complement(58319987..58339297)
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| AA seq |
1341 aa
MALILHFYVHPSGHEKAASGHTQRKLQGQLPALQGVKTELCYNVNWTAKSRPSAEEMKKL
TWLFGCPLLPGDVALESWLHPDCNDLLLEVGPRLNFSTPASTNVVSVCWAAGLGAVDRVE
TTRRYLLSFAQPPSAEMKAIALATLHDRMTEQHFPCPIQSFSLGSISTPLNSSINILAEG
RCALEKANQELGLALDSWDLDFYTKRFQELQRNPSTVEAFDLAQSNSEHSRHWFFKGLLH
MDGQKLAHSLFESIMSTQASSNPNNVLKFCDNSSAIQGKEVQFLRPEDPTQPSSFQQQRA
LRHVVFTAETHNFPTGVAPFSGATTGTGGRIRDIQCTGRGAHVVAGTAGYCFGNLHIPGY
NLPWEDPSFQYPENFARPLEIAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW
IKPIMFSGGIGSMEAEHVSKEPPEPGMDVVKIGGPVYRIGVGGGAASSVQVQGDNASELD
FGAVQRGDPEMEQKMNRVIRACVEASRGNPICSLHDQGAGGNGNVLKELSDPAGAVIYTS
RFQLGDPTLNALEIWGAEYQESNALLLRPLDRDFLSRVSARERCPACFVGTITGDRRIVL
VDDRECPVGRNGHEDGSPLSPPTPVDLELDWVLGKMPRKEFFLQRSFPVLKPLALPPGLR
VRQALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGALQTPLADVAVVALSHQELVG
AATALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAA
LADACEAMVAVMAALGVAVDGGKDSLSMAARVGSETVRAPGSLVISAYAVCPDITATVTP
DLKHPGGGGRLLYVPLSPGQHRLGGTALAQCFSQLGEQPPNLDVPENLAHAFNVTQGLLR
DRLLCSGHDVSDGGLITCLLEMAFAGNCGIEVDVPAPGVDVLPVLFAEEPGLVLEVQEAD
LGQVLERYWAAGLRCLELGPTGDAGPHALVRVSVNGAVVLEDTVGQLRAVWEETSFQLDR
LQAEPRCVAEEEQGLRERTGPSYCLPPTFPEASVPHEPGGPLPRVAILREEGSNGDREMA
DAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWGAAVTFHPLAG
AELRRFRKRPDTFSLGVCNGCQLLALLGWVGGSPSKEAQEAEEPGPDSWPTPPGLVLRHN
LSGRFESRWASVRVGSGPALMLRGMEGAVLPVWSAHGEGYMAFSSPELQAQIEAMGLAPL
HWADDAGQPTEQYPMNPNGSPGGVAGVCSLDGRHLALMPHPERAVRPWQWAWRPPPFDTL
TASPWLQLFINARNWTREGGC |
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| NT seq |
4026 nt +upstreamnt +downstreamnt
atggccttgattcttcacttctatgtccatccctctggccatgagaaggcagcttccgga
cacactcagcgaaagctccaagggcagctaccagcgctgcagggtgtcaagacagagctg
tgctacaacgtgaactggacagccaagtcccgtccgagtgccgaggagatgaaaaagctg
acatggctctttggctgtcccttgttaccgggggacgttgctctggaatcctggctccat
cctgactgtaatgacctgctgctggaggttgggcccaggctgaacttctccaccccagca
tccaccaacgtcgtgtcagtgtgctgggccgctgggctgggggctgtggatcgtgtggag
accacccggcgctacctgctttcgtttgcccaacccccatcagctgagatgaaggccatc
gccctggccaccctccatgaccggatgacggaacagcacttcccctgtcccatccagagc
ttctcccttgggagcatttccacgcccctcaacagctctatcaatatactcgctgagggc
cggtgtgccctcgagaaggccaaccaggagctgggcctggccctagactcctgggacctg
gatttctacaccaaacgcttccaggagctccagcggaaccccagcaccgtggaggccttc
gacttggctcagtccaatagtgaacacagccgacactggttcttcaaggggctgctccac
atggacgggcagaagttggcacactctctctttgagtccatcatgagcacccaggcgtcc
tcgaaccccaacaacgtcctcaagttctgtgacaacagcagcgcaatccaggggaaagaa
gtccaattcctacggcccgaggaccccacacagccaagcagcttccagcagcagcgggcc
ctgagacacgtcgtcttcacagcggagacccacaacttccccacaggagtggcccccttc
agcggtgcgaccacgggcactggaggccggatccgagacatccagtgcacaggccgtggg
gcccacgtggtggctggcaccgctggctattgctttggaaacctgcacatcccaggttat
aacctgccctgggaggatccaagcttccagtatcctgagaactttgctaggcccctggag
atcgccattgaggccagtaatggggcttctgattacggcaacaagtttggggagccagtg
ctggccggcttcgcccgctccttgggcctccagctccccgatggccagcggcgtgagtgg
atcaagcccatcatgttcagcgggggcatcgggtccatggaagctgaacacgtgagcaag
gaacccccagagccaggcatggatgtggtgaagattggggggcctgtctacaggatcgga
gttgggggtggagccgcatcgtctgtgcaggtgcagggcgacaatgccagcgagctggac
ttcggggccgtgcagcggggggacccggagatggaacagaagatgaaccgtgtgatccgg
gcttgtgtggaggcctccagggggaaccccatctgcagcctccacgatcagggcgctggc
ggcaatggcaacgtcctgaaggagctcagtgaccccgccggggctgtcatctacaccagc
cgcttccagctcggggatccgaccctgaacgccctggaaatctggggggctgagtaccag
gagtcgaatgctcttctgctgaggccccttgaccgggactttctcagtcgtgtcagcgcc
cgggaacgctgtccggcttgttttgtgggcaccatcactggggacaggaggatagtgctg
gtggatgatcgcgagtgccccgttggaagaaatggccatgaggatggctcccccttgtct
cccccaacccctgtggacctggagctggactgggtgctgggcaagatgcctaggaaggag
ttcttcctccagaggagtttccctgtgctgaagcccctggccttgcccccgggtctccgt
gtgcgccaggctctggagcgcgttctgaggctgcctgccgtggccagcaagcgctacctt
accaacaaggtggaccgctccgtgggcggcctggtggcccagcagcagtgtgtgggagcc
ctgcagacccccctggcagatgtggctgtcgtggccctgagtcaccaggagcttgttggg
gctgccaccgctctaggagagcagcctgtcaagagcctgctggaccccaaggtggctgcc
cgcctggccgtggccgaagccctcaccaacctggtgttcgcgctggtcaccgacctccgg
gacgtgaaatgcagcgggaactggatgtgggctgccaagctcccaggggagggcgcggct
ctggccgatgcctgcgaggctatggtggcagtgatggcggccttgggcgtggcagtggat
ggtggcaaggactctctcagcatggccgcccgggttggctctgagacagtgcgggctcct
ggatcgctggtcatctcagcctacgctgtctgtccagacattacggccactgtaacccca
gacctcaagcatcctggagggggaggccgtctgctgtatgtgcctctgagccctgggcag
caccggctggggggcacggctctggcccagtgcttctcacagctgggcgagcagcctccc
aacctggacgtccccgagaacttggcgcatgcctttaatgtcacccagggcctgctgaga
gaccgcctcctctgctcaggccatgatgtcagtgacgggggtctcatcacctgcctgctg
gagatggcctttgctgggaattgtgggatagaggtggatgtgcctgcccccggggttgac
gtgctgcccgtgctcttcgccgaggagccaggcctggtgctggaggtgcaggaggcagac
ctgggccaggtgctggagcgctactgggctgctggactccgctgcctggaactgggcccc
acaggcgatgccgggccccacgccctggtgcgagtgtccgtgaatggggcggtggtcctg
gaggacactgttgggcagctgcgcgccgtgtgggaagagacgagtttccagctggaccgg
ctgcaggcagagccgcgctgtgtggcagaggaagagcaggggctgcgggagcgcacagga
cccagttactgcctgcccccaaccttccccgaagcgtctgtgccccacgagcccggtggt
cccctgccccgagtcgccatcctgcgagaggagggcagtaacggagaccgtgagatggca
gatgccttccacttggctgggtttgaggtgtgggacgtgaccatgcaggacctgtgctct
ggggcaatcggcttggacactttccgtggtgtggcttttgtgggcggcttcagctatgcg
gacgtcctgggctctgccaaagggtggggggctgctgtgaccttccacccgctggccggg
gccgagctgaggcgcttccggaagcggcccgacacctttagcctgggcgtgtgtaacggc
tgtcagctgctggctctgctgggctgggtgggaggcagccccagcaaggaggcccaggag
gccgaggagccaggccccgactcctggcccacccctcctggcctcgtgctgcgccacaac
ctgtccggccgcttcgagtctcgctgggccagcgtgcgtgtggggtccgggccggccctg
atgctgcgagggatggagggcgccgtgctgcccgtgtggagcgctcatggggaaggttac
atggcattttcttccccggagctccaagcccagatcgaagccatgggcctggcgccactg
cactgggcagacgatgctgggcagcccacggaacagtaccccatgaaccccaatgggtcc
ccagggggcgtggctggcgtctgctccctcgatggccgccacctggctctcatgccacac
cctgagcgcgctgtgaggccatggcagtgggcgtggcgacctcccccgtttgacaccctg
acggcctccccctggctccagctcttcatcaacgcccgaaactggacccgggaagggggc
tgctga |
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