| Entry |
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| Symbol |
SREBF1
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| Name |
(RefSeq) sterol regulatory element-binding protein 1 isoform X1
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| KO |
| K07197 | sterol regulatory element-binding transcription factor 1 |
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| Organism |
mlk Mustela lutreola (European mink)
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| Pathway |
| mlk04932 | Non-alcoholic fatty liver disease |
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| Brite |
KEGG Orthology (KO) [BR:mlk00001]
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
131816222 (SREBF1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
131816222 (SREBF1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
131816222 (SREBF1)
04932 Non-alcoholic fatty liver disease
131816222 (SREBF1)
04931 Insulin resistance
131816222 (SREBF1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:mlk03000]
131816222 (SREBF1)
04131 Membrane trafficking [BR:mlk04131]
131816222 (SREBF1)
Transcription factors [BR:mlk03000]
Eukaryotic type
Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
Ubiquitous bHLH-ZIP factors
131816222 (SREBF1)
Membrane trafficking [BR:mlk04131]
Endoplasmic reticulum (ER) - Golgi transport
Others
Others
131816222 (SREBF1)
Autophagy
Mitophagy
Other mitophagy associated proteins
131816222 (SREBF1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
15:48831570..48853769
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| AA seq |
1147 aa
MDEPPFSEAALEQALAEPCELDAALLTDIEDMLQLINNQDSDFPGLFDPPYAGGGAGSTG
PASPDASTPGSLSPSPATMSSPLEGFLGGPKATPPPLSPPQPAPTSLKMYPSGPAFSPGP
GIKEEPVPLTILQPPTPQPLPGSLLPQSFPAPAPPQFSSAPVLGYPSPTGGFSAGTPPGS
TPQPLPGLPLASLPGVPPVSLHTQVQNAAPQQLLTATANPTAAPGTTTVTSQIQQVPVLL
QPHFIKADSLLLTTMKTDMAATVKAAGISSLAPGTAVQTAPLQTLVSGGTILATVPLVVD
AEKLPINRLAAGGKAPGSAQSRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNK
SAVLRKAIDYIRFLQQSNQKLKQENLSLRSAAHKSKSLKDLVSACGSGGNTDVHMEGMKP
EVVDTLSPPPSDAGSPSQSSPLSLGGRSSGSGGSGSDSEPDSPVFEDSQVKPEQLLSPRS
RGMLDRSRLALCALVFLCLSCNPLASLLGNRGLLSSSDVSSTYHGPGRNMLGAESGDGPG
WAPWLLPPLVWLTNGLLVLVFLALLFVYGEPVTRPHSDPAVHFWRHRKQADLDLARGDFA
QAAQQLWLALRALGRPLPTSHLDLACSLLWSLIRHLLQRLWVGRWLAGRAGGLHRDCALQ
ADARASARDAALVYHKLHQLHTMGKYTGGHLAAANLALSALNLAECAGDTVSVATLAEIY
VAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPLAMQWLCHPVGHRFFVDGDWAV
CSTPRESLYSLAGNPVDPLAQVTQLFREHLLERALNCVVQPSPSPGSADGDREFSDALGY
LQLLNSCSDAAGAPACSFSISSSMATATGTDPVAKWWASLTAVVTHWLRRDEEAAERLYP
VVEHLPRALQESERPLPRAALHSFKAARAVLGRGKAESGPASLAICEKASGYLQDSLATT
PAGSSIDKAMQLFLCDLLLVARTSLWRRQQPPAPTQTSQGPGAGAQASALELRGFQRDLS
GLRRLAQSFRPAMRRVFLHEATARLMAGASPTRTHQLLDRSLRRRAGPCGKGAGAELEPR
PTRREHAEALLLASCYLPPGFLSAPGQRVGMLAEAARTLEKLGDRRLLHDCQQMLMRLGG
GTTVTSS |
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| NT seq |
3444 nt +upstreamnt +downstreamnt
atggacgagccgcccttcagcgaagcggccttggagcaggcgctggccgagccgtgcgag
ctggacgcggccctgctgaccgacatcgaagacatgctgcagctcatcaacaaccaagac
agcgacttccctggcctgttcgacccaccctatgccggcggcggggcagggagcacaggc
cctgccagtcctgatgccagcaccccgggcagcttgtccccatctcctgccacaatgagc
tccccactcgaaggcttcctggggggacccaaggcgacacctccacccttgtcccctccc
cagcctgcacccacctccctgaagatgtacccctctgggcctgccttctccccggggcct
ggtatcaaggaggagccagtgccgctgactatcctgcagcccccaaccccgcagcccctg
ccggggtccctcctgccccagagcttcccggccccagctccaccacagttcagctctgcc
cctgtcttgggctatcccagccccacgggaggcttctctgcagggacccctccagggagc
accccgcagccgctgcctggcctgccactggcttccctgccaggggtcccgcccgtctcc
ttgcacacccaggtccagaacgcggccccccagcagctgttgacggccacggccaacccc
acggcagcccctggaacaaccacggtgacctcgcagatccagcaggtcccggtcctgctg
cagccacacttcatcaaggcagactcgctgctcctgacgaccatgaaaacagacatggca
gccactgtgaaggcggcgggtatcagctccctggcccctggcacagctgtgcagacggcg
cccttgcagaccctggtgagcggaggaaccatcctggcgacagtgccactggtagtggat
gccgaaaagctgcccatcaaccggctggcggctggtggcaaggcgccgggctctgcccag
agccgtggagagaagcgcacggcccacaacgccattgagaagcgctaccgttcttccatc
aacgacaaaatcgtcgagctcaaggacctggtagtgggcactgaggcgaagctgaataag
tctgccgtcttgcgcaaggccatcgactacatccgcttcctacaacagagcaaccagaag
ctcaagcaagagaacctgagtctccgctctgctgcccacaaaagcaagtctctgaaggat
ctggtctcagcctgtggcagtggaggaaacacagacgtgcacatggagggcatgaagcct
gaggtggtagacacactgagcccgcctccctcggacgctggctcgccctctcagagcagc
cccttgtccctcggaggcaggagtagtggcagtggcggcagtggaagcgactcggagccc
gacagcccagtctttgaggacagccaggtgaagcccgagcagctgctgtccccccgcagc
cggggcatgctggaccgctcccggctggccctgtgtgcactcgtcttcctctgcctttcc
tgcaaccccttggcctccctgctgggaaaccggggtctccttagctcctcagatgtcagc
agcacctaccatggtcctggccgcaacatgctgggtgctgaaagcggagacggccctggc
tgggccccatggctgctgcccccactggtctggctgaccaatgggctgctggtgctggtc
ttcctggcgcttctctttgtctatggagagccagtcacgcggccccactcggaccctgct
gtgcacttctggaggcatcgcaagcaggctgacctggacctggcccggggggactttgcc
caagctgcccagcagttgtggctggccctgcgggccctgggccgcccgctacccacctcc
cacctggacctggcctgcagcctgctctggagccttatccgccacctgctgcagcgcctc
tgggtgggccgctggctggccggccgcgctgggggcctgcacagggactgtgccctgcag
gcggacgcccgcgccagcgcccgggacgccgcacttgtctaccacaagctgcaccagctg
cacaccatggggaagtacacgggcgggcacctcgctgctgccaacctggccctaagcgcc
ctgaacctggcagaatgtgcaggggataccgtgtccgtggccacgctggccgagatctat
gtggctgccgcgctgagggtcaagaccagtctcccacgggccttgcattttctgacacgc
ttcttcctgagtagtgcccgccaggcctgcctggcacagagcggctcggtgcctcttgcc
atgcagtggctgtgccaccccgtgggccaccgtttcttcgtggacggggactgggccgtg
tgcagcaccccgagggagagcctgtacagcttggccggcaacccagtggacccattggcc
caggtgactcagctgttccgtgagcatctcctggagcgagcactgaattgtgtcgttcag
cccagtcccagccctggatcagctgatggagacagggagttctccgatgccctggggtac
ctccagctgctcaacagctgttctgatgccgctggggctccggcctgcagcttctccatc
agctccagcatggccactgccaccggcacagaccccgtggccaagtggtgggcctccctg
acagctgtggtaacccactggctgcgacgcgatgaggaggcggccgagcggctatacccg
gtggtggagcacctgccccgtgccctgcaggagtctgagagacccctgcccagggcagct
ctgcactccttcaaggctgcccgggctgtgctaggccgcgggaaagcagagtctggccca
gctagcctggccatctgtgagaaggccagtggatacctgcaggacagcctggccaccacc
ccagctggcagctccatcgacaaggccatgcagctgttcctgtgtgacttgctcctggtg
gcacgaactagcctgtggcggcgccagcagccgcctgctcccacccagacctcgcagggc
ccgggcgctggggcccaggcctctgccctcgaactgcgcggcttccaacgggacctgagt
ggcctgaggcgtctggcacaaagtttccggcctgccatgcggagggtgttcttgcacgag
gccacggcccggctgatggcgggggccagccccacgaggacacaccagctcctggaccgc
agtctgcggaggagggcaggaccctgtggcaaaggcgcaggggcggagctggaaccgaga
cccacgcggcgggagcacgctgaggctctgctgctggcctcctgctacttgcctcccggc
ttcctgtcggcgccggggcagcgcgtgggcatgctggccgaggcggcgcggacgctcgag
aagctcggcgatcgccgcctgctgcacgactgccagcaaatgctcatgcgcctgggcggc
gggaccaccgtcacctccagctag |
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