Mustela lutreola (European mink): 131816749
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Entry
131816749 CDS
T09578
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk00260
Glycine, serine and threonine metabolism
mlk00630
Glyoxylate and dicarboxylate metabolism
mlk00670
One carbon pool by folate
mlk01100
Metabolic pathways
mlk01200
Carbon metabolism
mlk01230
Biosynthesis of amino acids
mlk01240
Biosynthesis of cofactors
mlk01523
Antifolate resistance
mlk04981
Folate transport and metabolism
Module
mlk_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
131816749 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
131816749 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
131816749 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
131816749 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
131816749 (SHMT1)
Enzymes [BR:
mlk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
131816749 (SHMT1)
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GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
131816749
NCBI-ProteinID:
XP_059005675
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Position
15:48396012..48420985
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AA seq
483 aa
AA seq
DB search
MAEVNGTHKDADLWSSHNKMLAQPLKDGDTEVYDIIKKESNRQRVGLELIASENFASRAV
LEALGSCLNNKYSEGYPGQRYYGGTEFIDELEILCQKRALQVYGLDPKSWGVNVQPYSGS
PANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYI
NYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADENGAYLMADMAHISGLVAAGVV
PSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETLYNLESLINSAVFPGLQ
GGPHNHAIAGVAVALKQALTPEFRLYQRQVVANCQVLAQTLMELGYKVVTGGSDNHLILV
DLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQKV
AQFIHRGIELTLQIQNDIGAKATLKEFREKLAGDEKHQRAIRVLREEVESFASLFPLPGL
PEF
NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atggcagaagtcaatgggactcacaaggatgctgacctgtggtcctcacataataaaatg
ctggcgcagcccctgaaagacggcgacactgaggtttacgacatcatcaagaaagagagt
aaccggcagagggtcgggctggagctgatcgcctcagagaatttcgccagccgggcagtt
ttggaggccctaggctcttgcttaaataacaagtactctgagggatacccaggccagagg
tattatggcgggaccgagttcatcgatgagctggaaatcctctgtcaaaagcgagcgctg
caggtctatggtctggatcccaagagctggggggtcaatgtccagccctactcaggctcc
cctgccaacttcgcggtgtacaccgccctagtggagccgcacgggcgcatcatgggcctg
gacctgcccgacggtggccacctgacccacgggttcatgacagacaagaagaaaatctct
gccacgtccatcttttttgagtctatgccctataaggtgaacccagacactggctacatc
aactatgaccaactggaggaaaacgcccgcctcttccacccgaagctcattatcgcagga
accagctgctattcccgaaacctggactacgctcgactgaggaagattgcagacgagaat
ggggcgtatctcatggcggacatggcgcacattagcgggctggtggcagctggtgtggtg
ccctcaccctttgagcactgccacgtggtgtccaccaccacccacaaaaccctgagaggc
tgccgagccggcatgatcttctacaggaaaggagtgcgcagcgtggatcccaagacgggt
aaagagactctgtacaacctagagtcgctcatcaactctgccgtgttcccaggcctgcag
ggtggtccccacaaccacgccattgctggggtcgctgtggctctgaagcaggctctgact
cccgagttcagactttaccagcgacaggtggtggccaactgccaggtgctggcgcagacc
ctgatggagctgggctacaaagtggtaacaggtggttctgacaaccatttgatcctcgtg
gatctccgttccaaaggcacagatggcggaagggctgagaaggttctagaagcctgttct
attgcctgtaataagaacacctgtccaggtgacaaaagtgcactgcggcccagtggactg
cgtctggggactccagccctgacatcgagaggactattggaaaaagagttccagaaagta
gcccagtttattcaccgaggaatagaactgactttgcagatacagaatgacattggggcc
aaggccaccctgaaggagttcagagagaaactggcaggggacgagaagcaccaacgggcc
atcagggtgcttagggaggaagtggagagctttgcgtctctattccctctgcctggcctg
cctgagttctag
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