| Entry |
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| Symbol |
LRP5
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| Name |
(RefSeq) low-density lipoprotein receptor-related protein 5
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| KO |
| K03068 | low density lipoprotein receptor-related protein 5/6 |
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| Organism |
mlk Mustela lutreola (European mink)
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| Pathway |
| mlk04928 | Parathyroid hormone synthesis, secretion and action |
| mlk05022 | Pathways of neurodegeneration - multiple diseases |
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| Brite |
KEGG Orthology (KO) [BR:mlk00001]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
131816811 (LRP5)
04150 mTOR signaling pathway
131816811 (LRP5)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
131816811 (LRP5)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
131816811 (LRP5)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
131816811 (LRP5)
05226 Gastric cancer
131816811 (LRP5)
05224 Breast cancer
131816811 (LRP5)
09164 Neurodegenerative disease
05010 Alzheimer disease
131816811 (LRP5)
05022 Pathways of neurodegeneration - multiple diseases
131816811 (LRP5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:mlk04131]
131816811 (LRP5)
Membrane trafficking [BR:mlk04131]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
131816811 (LRP5)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
1:285476708..285574728
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| AA seq |
1606 aa
MEAAPPRLLLLALCCSLAPAAASPLLLFANRRDVRLVDAGGVKLESTIVVSGLEDAAAVD
FQFSKGAVYWTDVSEEAIKQTYLNQTGVAVQNVVISGLVSPDGLACDWVGKKLYWTDSET
NRIEVADLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGETPRIERAGMDGSTRKII
VDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDT
LYWTDWQTRSIHACNKRTGEKRKEILSALYSPMDIQVLSPERQPYFHTRCAEDNGGCSHL
CLLSPREPFYTCACPTGVQLHDNGKTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQV
DDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARN
LYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGENPKIERANL
DGQERHILVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIF
GFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNVAKAVGTNACADGN
GGCSHLCFFTPHAAKCGCPIGLELLSDLKTCIVPEAFLVFTSRAAIHRISLETNNNDVAI
PLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPEGMAVDWVG
KNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRA
FMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDTNMIESSDMLGQERVVIADDLPHPF
GLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCMHN
NGQCGQLCLAVPGGHRCGCASHYTLDPSSRNCSPPTTFLLFSQKCAISRMIPDDQHSPDL
ILPLHGLRNVKAIDYDPLDKFIYWVDGRQNIKRAKDDGTQPFVLTSPSPSQNPDRQPHDL
SIDVYSRMLFWTCEATNTINVHRLNGDAMGVVLRGDRDKPRAIVVNAERGYLYFTNMQDR
AAKIERAALDGTEREVLFTTGLIRPVALVVDNRLGKLFWVDADLKRIESCDLSGANRLTL
EDANIVQPAGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRVQGRVAHLTGIHAVEEISL
EEFSAHPCARDNGGCSHICIAKGDGTPRCSCPVHLVLLQNLLTCGEPPTCSPDQFACATG
EIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGEADCQDRSDE
ADCDAICLPNQFRCASGQCVLIKQQCDSFPDCIDGSDELMCEITKPPSDDSPAHSSAIGP
VIGIILSLFVMGGVYFVCQRVLCQRYAGASGPFPHEYVSGTPHVPLNFIAPGSSQHGPFT
GISCGKSMMSSVSLMGGRGGVPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPS
LYNVDMFYSSNIPTTARPYRPYIIRGMAPPTTPCSTDVCDSDYSASRWKASKYYLDLNSD
SDPYPPPPTPHSQYLSAEDSCPPSPATERSYFHLFPPPPSPCTDSS |
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| NT seq |
4821 nt +upstreamnt +downstreamnt
atggaggcggcgccgccgcggctgctgctgctcgcgctctgctgcagcctggcccccgcc
gcggcctcgcctctcctgctgttcgccaaccgccgggacgtgcggctggtggacgccggc
ggagtcaagctggagtccaccatcgtggtcagcgggctggaggatgcggccgccgtggac
ttccagttctccaagggagccgtgtactggacggacgtgagcgaggaagccatcaagcag
acctacctgaaccagacgggggtcgccgtgcagaacgtggtcatctccggcctggtgtcc
cccgacggcctggcctgcgactgggtcggcaagaaactgtactggacggactcggagacc
aaccgcatcgaggtggccgacctcaacgggacgtcgcggaaggtcctcttctggcaggac
ctcgaccagccacgggccatcgccttggaccccgctcacgggtacatgtactggacagac
tggggcgaaacacctcgaatcgagcgagcaggcatggacggcagtacccggaaaatcatc
gtggactccgacatctactggcccaacgggctgaccatcgacttggaggagcagaagctc
tactgggccgacgccaagctcagcttcatccaccgtgccaacctggatggctcgttccgg
cagaaggtcgtggagggcagcctgacgcacccctttgcgctgacactctctggggacact
ctgtactggacggactggcagacccgctccatccacgcctgtaacaagaggaccggagag
aagaggaaggagatcctcagcgccctctactcgcccatggacattcaagtgctcagcccg
gagcggcagccttacttccacacacggtgtgcagaggacaacggcggctgctcccacctg
tgcctgctgtccccgagggagcctttctacacgtgcgcctgccccaccggtgtgcagctc
catgacaacggcaagacgtgcaaggcaggagccgaggaggtgctgctgctggcccggcgg
acggatctgcggaggatctcgctggacacgccggacttcaccgacatcgtgctgcaggtt
gatgacatccgacatgccattgccatcgactacgacccgctggagggctatgtctactgg
acggacgacgaggtgcgggccatccgcagggcgtacctggatgggtcaggcgcacagacg
ctggtcaataccgagatcaacgaccccgacggcatcgcggttgactgggtggcccgcaac
ctctactggacggacacgggcaccgaccgcatcgaggtgacacgtctcaatggcacctcc
cgcaagatcctggtgtccgaggacctggacgagccccgggccattgtcctgcaccctgtg
atgggcctcatgtactggacagactggggggagaaccccaaaatcgagcgcgctaacctg
gatggacaggagcggcacatcctggtgaacacgtccctcgggtggcccaacggcttggcc
ctggacctgcaggagggaaaactgtactggggagatgccaagacggacaaaatcgaggtg
atcaacgttgatgggacaaagaggcggacactcctggaagacaagctcccccacattttc
gggttcacgctgctgggggacttcatctactggaccgactggcagcgtcgcagcatcgag
cgcgtgcacaaggtcaaggccagccgggacgtcatcatcgaccagctgcccgacctgatg
gggctgaaggccgtgaacgtggccaaggctgtcggaaccaacgcgtgtgcggacgggaac
gggggctgcagccacctgtgcttcttcacgcctcacgccgccaagtgcggctgccccatc
ggcctggagctgctgagcgacctgaagacctgcatcgtccccgaggccttcctggtgttc
accagccgagccgccatccacaggatctccctggagaccaacaacaacgacgtggccatc
ccgctgacgggcgtcaaggaggcctcggcgctggacttcgacgtgtccaacaatcacatc
tactggacggacgtcagcctgaagaccatcagccgagcgttcatgaacgggagctccgtg
gagcacgtgatcgagtttggcctcgactacccggaaggcatggctgtcgactgggtgggc
aagaacctctactgggcggacactgggaccaacaggatcgaagtggcccggttggacgga
cagttccggcaggtccttgtgtggagggacctggacaacccgaggtcactggccctggac
cccaccaaaggctacatctactggactgagtggggggggaaacccaggattgtgcgggcc
ttcatggacgggaccaactgcatgacgctggtggacaaggtgggtcgggccaacgacctc
accatcgactacgctgaccagcgtctctactggaccgacctggacaccaacatgatcgag
tcatccgacatgctgggtcaggagcgcgttgtgatcgcggacgaccttccgcaccccttc
ggcctgacgcagtacagcgattacatctactggaccgactggaacctgcacagcatcgag
agggccgacaagaccagcggccggaaccgcaccctcatccagggccacctggacttcgtg
atggacatcctggtgttccactcctcccgccaggatggcctcaacgactgcatgcacaac
aatgggcagtgcgggcagctgtgcctcgccgtccccggcggccaccgctgtggctgtgcc
tcacactacaccctggaccccagcagccgcaactgcagcccgcccaccaccttcttgctg
ttcagccagaaatgtgccatcagccgcatgatccccgacgaccagcacagcccagacctc
atcctgcccctgcacgggctgaggaacgtcaaggccatcgactatgaccccctggacaag
ttcatctattgggtggacggacgccagaacatcaagcgagccaaggacgacgggacccag
cccttcgttttgacctcgccgagcccgagccagaacccggacaggcagccccacgacctc
agcatcgacgtctacagccggatgctcttctggacgtgtgaggccaccaacaccatcaac
gtccaccggctgaatggagacgccatgggtgtggtgctccgtggggaccgcgacaagccg
cgggccatcgtcgtcaacgccgagcgggggtacctgtacttcaccaacatgcaggaccgc
gcggccaagatcgagcgagcggccttggatggcaccgagcgtgaggtcctgttcaccacg
ggcctcatccggcccgtggccctcgtggtggacaacaggctcggcaagctcttctgggtg
gacgcggacctgaagcgcatcgagagctgtgacctgtcaggggccaaccgcctgaccctg
gaggacgccaacatcgtgcagccggcaggcctgaccgtgctgggcagacacctctactgg
atcgaccggcagcagcagatgattgagcgtgtggagaagaccaccggcgacaagcggacg
cgggtccagggccgcgtcgcccacctgactggcatccacgccgtggaggagatcagcctg
gaggagttctcggcccacccatgcgcccgggacaacggcggctgctcccacatctgcatt
gccaagggcgacgggaccccacggtgctcctgcccagtccaccttgtgctcctgcagaac
ctgctgacctgtggcgagcctcccacctgctcccccgaccagttcgcctgtgccactggg
gagattgactgcatccctggggcctggcgctgcgacggcttccccgagtgtgacgaccag
agcgacgaggagggctgccctgtgtgctcagccgcccagttcccctgtgcgcggggccag
tgcgtggacctgcgcctgcgatgcgacggtgaagccgactgccaggaccgctccgacgag
gctgactgcgatgccatctgcctgcccaaccagttccgctgcgccagcggccagtgcgtc
ctgatcaagcagcagtgcgactccttccccgactgcatcgacggctccgatgagctcatg
tgcgagatcaccaagccaccgtccgacgacagcccggcccatagcagcgccatcgggcct
gtcatcggcatcatcctgtccctgtttgtcatgggcggggtctacttcgtgtgccagcgt
gtgctgtgccagcgctacgccggggccagtgggcccttcccgcatgagtacgtcagtggg
accccccacgttcccctcaatttcatagcccccggcagctcccagcatggtcccttcaca
ggcatctcatgtggcaagtccatgatgagctccgtgagcctgatggggggccggggtgga
gtgcccctctatgaccggaaccacgtcaccggggcctcgtccagcagctcgtctagcacc
aaggccactctgtacccgccgatcctgaacccgccaccgtcccccgccacggacccctct
ttgtacaacgtggacatgttctactcttcaaacattcccaccaccgcaagaccctacagg
ccctacattatccgaggcatggcccccccgacgacgccctgcagcacggacgtctgtgac
agcgactacagcgccagccgctggaaggccagcaagtactacctggacttgaactcggac
tcagacccctacccgccgccgcccacgccccacagccagtacctgtcggcggaggacagc
tgccccccttcgcccgccaccgagaggagctacttccacctcttcccgccccctccgtcc
ccctgcacagactcctcctga |
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