Mustela lutreola (European mink): 131816957
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Entry
131816957 CDS
T09578
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk04140
Autophagy - animal
mlk04141
Protein processing in endoplasmic reticulum
mlk04210
Apoptosis
mlk04932
Non-alcoholic fatty liver disease
mlk05010
Alzheimer disease
mlk05012
Parkinson disease
mlk05014
Amyotrophic lateral sclerosis
mlk05016
Huntington disease
mlk05017
Spinocerebellar ataxia
mlk05022
Pathways of neurodegeneration - multiple diseases
mlk05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
131816957 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
131816957 (ERN1)
09143 Cell growth and death
04210 Apoptosis
131816957 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
131816957 (ERN1)
05012 Parkinson disease
131816957 (ERN1)
05014 Amyotrophic lateral sclerosis
131816957 (ERN1)
05016 Huntington disease
131816957 (ERN1)
05017 Spinocerebellar ataxia
131816957 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
131816957 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
131816957 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
131816957 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlk01001
]
131816957 (ERN1)
Enzymes [BR:
mlk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
131816957 (ERN1)
Protein kinases [BR:
mlk01001
]
Serine/threonine kinases: Other
IRE family
131816957 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Motif
Other DBs
NCBI-GeneID:
131816957
NCBI-ProteinID:
XP_059006187
LinkDB
All DBs
Position
15:14476783..14553991
Genome browser
AA seq
975 aa
AA seq
DB search
MPARLLLVLLALLLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCQSSEGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLKKV
LHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTEGVTIGDKGECVITPSTDVKFDPGLKGKNKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSDKKSFEEVINLVDQTSENAPTTVSQ
DVEEKYERAPAKPEAPMDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQ
KELEKIQLLQQQQLPFHPPGDVAQDAEPLDLSGLYSESSGTSSPSTSPRASNHSLHSSGS
ASKAGSSPFLEQDDEDEETNMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPEKHEDVIARELIENMIAMEPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLR
AMRNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMEPCSHERLFQPYYF
HEPPEPWPPVTADTP
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctgctgctggtgctgctggcgctgctgctgcctggccccgggattttt
ggaagtcccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaactctggatgga
agtttgcatgctgtcagcaagaggacaggctcgatcaaatggactttaaaagaagatcca
gttctgcaagttccaacacatgtggaagagcctgccttcctcccagatcccaatgacggc
agcctgtatacgcttggaggcaagaataatgaaggcctgacgaaacttccttttaccatc
ccagagttggtacaggcatccccatgccaaagttcagaaggaattctctacatgggtaaa
aagcaggacatttggtatgtcattgaccttctgaccggggagaagcaacagactctgtcg
tcggcctttgcagacagtctctgcccgtcaacctctttgctgtatcttgggcgaacagaa
tacaccatcaccatgtacgacaccaaaacccgcgagctccggtggaacgccacctacttc
gactacgcagcctcactgcctgaggacgacggggactacaagatgtcccactttgtgtct
aatggcgacgggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaa
aactacgcttcgcccgtggtggccttttacgtctggcagcgggagggtctgaagaaggtg
ctgcacatcaacgtcgctgtggagaccctgcgctacctgaccttcatgtccggggaggtg
ggccgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctg
acgcccaccctgtatgtcgggaagtactctaccagcctgtatgcctccccctccatggtt
cacgagggagtcgccgttgtgccccgaggcagcactctgcctttgctggaaggcccccag
actgagggggtcaccatcggggacaaaggggagtgtgtgatcacacccagcacagacgtc
aagtttgaccctgggctcaaaggcaagaacaagctcaactacctgaggaactactggctt
ctgataggacaccatgaaacccccctgtccgcgtctaccaagatgctggagagattcccc
aacaacctgcccaaacatcgggaaaacgtgattcctgccgactcagacaagaagagcttc
gaggaagttatcaacctggttgaccagacttcagaaaacgcgcctaccaccgtctcacag
gatgtggaagagaaatacgagcgtgccccagccaagcctgaggcccccatggactctgtg
cttaaggacatcgccaccatcatcctgagcaccttcctgctcatcggctgggtggccttc
atcatcacctaccccttgagcatgcatcagcagcagcagctccagcaccagcaattccag
aaggaactagagaaaatacagctcctgcaacagcagcagctgcccttccatccacctgga
gacgtggctcaggatgctgagcccttggacttgtccggcctgtactcggagagctcgggc
accagcagccccagcacgtcccccagagcctccaaccactcgctgcactccagtggctct
gcctccaaggctggcagcagcccctttctggagcaggacgatgaggatgaggaaaccaac
atggtgatagttgggaagatttcattctgtcccaaggacgtgctgggtcatggagctgag
ggcacgattgtgtaccggggcatgtttgacaaccgtgacgtggctgtcaagaggatcctt
cccgagtgtttcagtttcgcggaccgtgaggtccagctgcttcgagaatccgatgagcac
cccaacgtgattcgctacttctgcacggagagggaccgacagttccagtacattgccatc
gagctgtgcgccgccaccctgcaggagtacgtggagcagaaggactttgcccacctcggc
ttggagcccatcaccctgctgcagcagaccacctcgggcctggcgcatctgcactccctc
aacattgttcacagagacctgaagccccacaacattctcctctccatgcccaacgcacat
ggcaggatcaaggccatgatttcggacttcggcctgtgcaagaagctagctgtaggcagg
cacagtttcagccgccgctccggagtgccgggcacggaaggctggatcgccccagagatg
ctgagcgaagactgcaaggacaaccctacctacacggtggacatcttctctgcgggctgt
gtcttttactacgtgatatcggagggcagccacccttttggcaagtccctgcagcggcag
gccaacatcctcctgggagcctacagcctggactgcctgcaccctgagaagcacgaagac
gtcattgcccgggaattaatagagaacatgatcgccatggagcctcagaagcgcccgtcc
gcgaaacatgtgctgaagcacccgttcttctggagcctggagaagcagctgcagttcttc
caggacgtgagtgaccgaatagaaaaggagtccctggacggcccgatagtgaagcagctg
gagcgaggcgggagagctgtggtgaagatggactggagagagaacatcaccgtccccctg
cagacagatctgcggaaattcaggacctataaaggcggctccgtccgagacctcctccga
gccatgagaaacaagaagcaccactaccgggagctccccgcggaggtgcgggagacgctg
ggctccctccccgacgacttcgtgcgctacttcacgtcccgcttcccccacctcctctcc
cacacctaccgggccatggagccgtgcagccacgagcggctcttccagccctactacttc
cacgagcccccagagccctggcctccagtgactgcagacaccccttga
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