| Entry |
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| Symbol |
KMT2B
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| Name |
(RefSeq) histone-lysine N-methyltransferase 2B isoform X1
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| KO |
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| Organism |
mlk Mustela lutreola (European mink)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:mlk00001]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
131818658 (KMT2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:mlk03000]
131818658 (KMT2B)
03036 Chromosome and associated proteins [BR:mlk03036]
131818658 (KMT2B)
Enzymes [BR:mlk01000]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
131818658 (KMT2B)
Transcription factors [BR:mlk03000]
Eukaryotic type
Zinc finger
CXXC CpG-binding proteins
131818658 (KMT2B)
Chromosome and associated proteins [BR:mlk03036]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
131818658 (KMT2B)
HMT complexes
MLL3/MLL4 complex
131818658 (KMT2B)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
16:42621684..42641611
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| AA seq |
2736 aa
MAAAAGGGSCPGPGSARGRFPGRPRGSGGGGGRGGRGSGAERVRVALRRGGGAGGPGGAE
PGEDTALLRLLGLRRGLRRLRRLWAGPRIQRGRGRGRGRGWGPSRGCVPEEESSDEESDD
EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPIPPPRLADVAPTPPKTPARK
RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRKKQQAVVV
AEAAVTIPKPEPPPPVVPVKHRTGSWKCKEGPGPGPGTPKRGGQSGRGGRGGRGRGRGGL
PLVIKFVSKAKKVKMGQLSLGLESGQGQDQHEESWQDALQAKVGSGQGEGPCWRKEQKLE
EEEEEETEEEKDKEEKEEKVERAGPEEEMMLAEEKEEAKLPSPPSTPPAPPAPPPAPSSP
PPPLPPLPPPLPPPSTSPSSPVCPPPLPVSPLPPPSPPPPPAPEEQEESPPPVVPATCSR
KRGRPPLTPSQRAEREAARAVPEGTSPPTPTPSTTTGGPLEDGPTVAPKSTTFLKNIRQF
IMPVVSARSSRVIKTPRRFMDEDPPKPLKVEVSPVLRPPVATSPLAPPEPAPAPSPPRAP
TPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPAPPPPPAPVTPSRRPLLLRA
PQFTPSEAHLKIYESVLTTPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPV
VATPVKAEAPLPAAPSLSNGQQSQAQLQQPLQALSSQLLPQALPPQQPQLQAHLQLQPQP
PPQQLSPLEKARTAGLGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQQKVASLMPPSPG
GQMEEVVGTVKQISDRGSVKSEDESMETKRERPSGPESPVQGPRIKHVCRHAAVALGQAR
AMVPEDVPRLSALPLRDRQDLVTEDTSSASETESVPSRSRRGKVESAGPGGDSEPAGSGG
TLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYR
KCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAPPG
PEEQDSLLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPVPEPEEQS
RPRKPTLQPVLQLKARRRLDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLE
NVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHD
TWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVR
CKSCGATPGKNWDVEWSGDYSLCPRCTQLFEKGNFCPICTRCYEDNDYESKMMQCAQCDH
WVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAGATHPRWREALSGALQGGLRQVLQGLLS
SKVAGPLLLCTQCGQAGKQLHPGPCDLQAVSRRFEEGHYKSVHSFMEDMVGILMRHSEEG
EGTQPERRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVY
AQWRQQEPETPESGQPPGDPSAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLY
IGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLS
NFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVTPDGFDVLRRVYVDFEGINFKRKFL
TGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRI
LEYRPWGPREEPVHLEAAEENQTIVHSPAPSSEPPDHVDPPPDIDALIPGAPEHHSPVQN
LDPPLRPDPSSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPT
VGDLDFPAPPRRSRRPSPLAPRLPASRRASPPLRTSPQLRVPPPTSVVRALTPTSGELAP
PGPAPSPPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGVVGSGHGG
PGDSSEEEASPTPRYVHFPVTVVSGPALAPGALPGAPRIEQLDGVDDGTDSEAEAIQQPR
GQGTPPSGPGVGRAGVIGAAGDRTRPPEDLPSEIVDFVLKNLGGPGEGGAGPREEPLPPA
PPLANGSQPPQGLPSNPADPTRTFAWLPGAPGVRVLSLGPTPEPPKPATSKIILVNKLGQ
VFVKMAGEGEPVSPPVKQPPLPPPIPPTAPASWTLPPGPLLGVLPVVGVVRPAPPPPPPP
LTLVLSSGPPSPPHQAIRVKRVSTFSGRSPPAPPPNKNPRLEEDGESLEDAPQGPGLSGS
GFSRVRMKTPTVRGVLDLDEPGEPTGEESPRPLQDRSPLLPLPEGGPPRAPDGPPDLLLE
SQWHHYSGEASSSEEEPPSPEDKENQAPKRAGPHLRFEISSEDGFSVEAESLEGAWRTLI
EKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQ
EEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLE
LPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREK
FYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRR
ILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN |
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| NT seq |
8211 nt +upstreamnt +downstreamnt
atggcggcggcggcgggcggcggcagttgccccgggcctggctccgcgcggggccgcttc
ccgggccggccgcggggctccggcgggggcgggggccgcggcggacggggcagcggagcc
gagagagtgcgggtagctctgcggcgcggcggcggcgcgggggggccgggcggagccgag
cccggggaggacacggccctgctccgtttgctggggctccgccggggcctgcgccggctc
cgccgcctgtgggctggcccgcgcattcaacggggccggggccggggccggggccggggc
tggggcccaagccgtggctgcgtgccggaggaggagagcagtgacgaggaatccgacgat
gaggagtttcagggttttcattcagatgaagatgtggcccccagttccctgcgctctgcg
ctccgatcccagcgaggtcgagccccccgaggtcggggccgcaagcataagacgaccccc
attccgcctcctcgcctagcagatgtcgctcctacccccccaaagactcctgctcggaaa
cggggtgaggagggcacagaacggatggtgcaggcactgactgaacttcttcggcgggcc
caggcaccccaagccccgcggagccgggcatgtgagccctccactccacgtcggtctcgg
ggacggcccccaggacggccagcaggcccctgcaggaaaaagcaacaagcagtagtggtg
gcagaagcagctgtgacaatccccaaacctgagcccccacctcctgtggttcctgtaaaa
catcgaactggcagctggaagtgcaaggaggggcctggcccaggacctgggacccccaag
cgtggaggacagtctgggcgaggaggccgtggaggtagaggccgaggccgaggcgggctc
cctctcgtaatcaagtttgtttcaaaggccaaaaaagtgaagatgggacagttgtccttg
ggactcgaatcaggtcagggtcaagatcaacatgaagaaagctggcaggatgccctccaa
gcaaaagttggatctggacagggagagggcccttgctggagaaaagagcaaaagctagag
gaagaggaagaggaggagacggaagaagagaaagacaaggaagagaaagaggaaaaggta
gagagagctggacctgaagaagagatgatgctagcagaggaaaaggaagaggcaaagctg
ccatctccaccctccactcctccagcccctccagcccctccacctgctccatcttctcca
cctcctccacttccaccactgcctccacccctcccacccccctccacttctccttcatcc
ccagtttgccctccaccactcccagtgtcccctctgcccccaccatcgcctccaccgcct
cctgccccagaggagcaggaagaatcccctcctccagtggtcccagctacatgctccagg
aagaggggccggcctcccctgacccccagccagcgggcagagcgagaagctgctcgggca
gtgccggagggtacctctcctcccactccaacccccagcaccaccacggggggccctcta
gaagacggccccactgtggcccccaaaagtaccaccttcctgaagaatatccggcagttt
attatgcctgtggtgagtgcccgctcctcccgagtcatcaagacaccccggcgatttatg
gacgaagacccccccaaacccctaaaggtagaagtctcacctgttctgcggcctcctgtt
gccacctccccacttgcccccccagaaccagcaccagctccctctccaccgcgtgcccca
acccccccatctaccccagtcccactccctgagaagagacggtccattctaagggaaccc
acatttcgctggacctcgctgacccgggaactgccccctcctcctcctgcccccccaccg
gccccacccccacctcctgcccctgtcactccatcgcggagacccctgctccttcgggca
cctcagtttaccccgagtgaagcccacttgaagatctacgaatcggtgcttactactcct
cttggggccccggaagcccctgagccagagccgcctcctgccgacgactctccagctgag
cctgagccacgggcagtgggccgcaccaaccacctcagcctgcctcgatttgcccccgtg
gtcgccactcctgttaaggccgaggcgccccttcctgcggctccgtctctgagcaatggg
cagcagtctcaggctcagttacagcagcccctccaggccttgtcaagccagctgctgccc
caggcgctaccaccacagcagccccaactacaagcgcacttacagctgcagccacagcca
ccgccgcagcagctgtcaccactggaaaaggcccgtactgcgggcttgggttccttacca
ctgtctggtgtggaggagaaaatgttcagcctcctcaagagagccaaggtgcagctgttc
aagattgatcagcagcagcagcagcagaaggtggcgtctttgatgccgccgagtcctgga
gggcagatggaggaagtcgtggggactgtcaagcagatctcagatagaggttctgtcaag
tctgaagatgaatcgatggaaactaagagagagagaccgtcgggccctgagtcccctgtg
caaggcccccgtatcaaacatgtctgtcgtcatgctgctgtggccctaggtcaggcccgg
gccatggtgcccgaagacgtcccccgcctcagtgctctccctctccgggatcggcaggac
ctcgtcacggaggatacatcatcagcatctgagactgagagtgtcccgtcacggtctcgg
cggggaaaagtggagtcagcagggcctgggggagactcagagcctgcagggtctggaggg
accctggcccatacaccccggcgctcactgccctcccatcatggcaagaagatgaggatg
gcacggtgtggacattgtcggggctgcctgcgtgtgcaggactgtgggtcctgtgtcaac
tgcctggacaagcccaaatttgggggccccaacaccaagaagcagtgctgtgtataccgg
aagtgtgacaagatagaggctcggaagatggaacggctggctaaaaaaggccggacgata
gtgaagacgctgttgccctgggattccgatgaatctcctgaggcctcccctggtcctcca
ggcccacgccggggggcgggagctggggggccccgggaggaggtggtggcccccccaggg
cccgaggagcaggactccctcctactgcagcgcaagtcagcccggcgctgcgtcaaacag
cgaccctcctatgatatcttcgaggactcggatgactcagagcctgggggtccccctgct
ccccggcgtcggaccccccgagagaatgagctgccagtgccagaacccgaggagcagagc
cggccccgcaaacccaccctgcagcctgtgttgcagctcaaggcccgaaggcgcctggac
aaggatgctttggctcctggcccctttgcctcttttcccaatggctggactggaaaacag
aagtcccctgacggagtgcaccgggtccgtgtggattttaaggaggattgtgacctggag
aacgtgtggctgatgggcggcctgagcgtgctcacctccgtgccaggggggccgccgatg
gtgtgcttgctgtgtgccagcaaaggcctgcatgagctggtgttctgccaagtctgctgt
gaccctttccatccattctgtctggaggaggccgagcggcccctgcctcaacatcatgac
acctggtgctgccgccgctgcaagttttgccatgtctgtgggcgcaaaggccggggatcc
aagcacctcctggagtgtgagcgctgccgccatgcttaccacccagcctgtctggggccc
agctacccaactcgggccacacgcaaacggcgccactggatctgctcggcctgcgtgcgc
tgtaagagctgtggggcaactccaggcaagaactgggacgtcgagtggtctggagattac
agcctctgccccaggtgcacccagctctttgagaaaggaaacttttgcccaatctgtaca
cgctgctacgaagacaacgactacgagagcaagatgatgcagtgcgcacagtgtgaccac
tgggtgcatgccaagtgtgaggggctctcggatgaagactatgagatcctttctgggctg
ccagactccgtgctgtacacctgcggaccgtgtgcaggggccacacacccccgttggcga
gaggccctgagtggggccctgcaggggggcctgcgccaggtgctccagggtctgctgagc
tccaaagtggcgggcccactgctgctgtgcactcagtgtgggcaggctggaaagcagctg
cacccaggcccctgcgatctgcaagctgtgagtcggcgcttcgaggaaggccattacaag
tctgtgcacagctttatggaggacatggtgggcatcctgatgaggcactcagaagaagga
gaaggcactcagccagagcgccgggctggaggccagatgaaggggctcctactgaagctg
ctagagtctgcgttcggctggttcgacgcccacgaccccaagtactggcgacggagtacc
cggctgccgaacggagttcttcccaatgccgtgttgcccccgtccttggaccatgtctac
gctcagtggaggcagcaggaacctgagaccccagaatcagggcagcctccaggggacccc
tcagcagcttttcagggtaaggatccagctgctttctcacacctggaggaccctcgtcag
tgtgcgctctgcctcaaatacggggatgcagattctaaggaggcaggacgactcctatac
atcgggcagaatgagtggacacacgtcaactgtgccatttggtcagctgaagtgtttgag
gaaaatgatggctccctcaaaaatgtgcatgctgctgtggctcgagggaggcagatgcgc
tgtgaactctgcctgaagcctggagccacagtgggctgctgcctttcctcctgcctcagc
aacttccatttcatgtgtgcccgggccagctattgcatcttccaggatgacaagaaagtt
ttctgccagaaacacacagacctgctggatggcaaggagattgtgacccctgatgggttt
gatgttctccgccgagtctacgtggactttgagggcatcaactttaagcgaaagttcttg
acggggctggaacctgatgccatcaatgtgctcattggctccatccgaattgactccttg
ggtaccttgtctgatctctcggactgcgagggacggctcttccccattggctaccagtgt
tcccgtctgtactggagcacagtggatgctcgacggcgctgctggtatcggtgtcgtatt
ctggagtatcggccatggggtccgagggaagagccggttcacctggaggcagcagaggag
aatcagaccattgtgcacagccctgccccttcctcagagcccccagatcatgtggacccc
cctccagatatagatgccctcatccccggagctcctgagcaccactcacctgttcagaac
ctggaccccccacttcggccagatccaagcagtgcccctcctccggccccccgctccttc
tcgggggctcgaatcaaagtgcccaactactcaccatcccggaggcccttggggggtgtc
tcctttggacccctgccctcccctggaagtccatcttctctgacccaccacatccccacg
gtgggagacctggacttcccagctccccccagacgttcccgtcgtcccagccccctggcc
ccaaggctgccggcctcacggcgggcctctccccctctcagaacctccccacagctcagg
gtgccccctcctacctcagtcgttagagccctcacacctacctcaggggagctggctccc
cctggcccagccccatctcctccaccaccccctgaagacctgggtccagactttgaggac
atggaggtggtatcaggactgagtgctgctgacctggactttgcggccagcctgctgggg
actgagcccttccaggaagagattgtggctgcaggggtagtggggagcggccacgggggc
ccaggggacagttcagaggaagaggccagccctaccccccgctatgtccacttccctgtg
actgtggtgtctggccctgcccttgcccctggcgcccttcctggagccccccgcatcgaa
cagctggatggagtggatgacggcacggacagcgaggcagaggccatccagcagcctcgg
ggtcaggggactcctccttcagggccaggagtgggccgggctggggtcatcggggctgca
ggggacagaacccgacctcctgaggacttgccgtcagaaattgtggattttgtgttgaag
aacctaggggggcccggggagggaggtgctgggcccagagaggagccgcttcccccagca
cctccactggctaatggcagccagcctccccagggcctaccctccaacccagctgacccc
actcggacgtttgcctggctccctggggccccaggggtccgggtattgagcctgggccct
acccctgagccccccaaacccgccacatccaaaatcatccttgtcaacaagctcgggcaa
gtgttcgtcaagatggctggggagggtgaacccgtctcacccccagtgaagcagccacct
ctgccccctcccatcccccccacagcccctgcttcctggactctgcccccgggaccgctg
ctgggtgtgttgccagtggtaggagtggtccgccctgcccccccaccaccccctcctcca
ctgacactggtgttgagcagtgggccccccagcccaccccatcaggccatccgcgtcaag
agggtgtccaccttctctggccgttccccaccagcgcctcccccaaacaagaacccccgg
ctggaggaagatggagagtccttggaggatgctccccagggtccagggcttagtggcagc
gggtttagccgagtgaggatgaaaacgcccacagtgcgtggagttctcgacttggatgag
cctggggagcccactggggaggaaagtccaaggcccctccaggaccggtcccccttgctg
ccactcccagaaggtggtcctccccgggcccccgatggtccccctgacctgctgcttgag
tcccagtggcaccactactcaggtgaggcgtcaagctctgaggaagagcctccatcccca
gaggacaaagagaaccaggcccccaaacgggctggcccgcatctgcgcttcgagatcagc
agtgaggatgggttcagtgtggaggcagagagcttggagggggcatggagaactctgatt
gagaaggtgcaagaggcccgagggcatgcccggctccggcatctctccttcagtgggatg
agtggggcaaggctcctgggcatccaccacgacgccgtcatcttcctggcagagcagctg
cctggggcccagcgctgccagcactacaagttccgctaccaccagcagggagagggccag
gaagaaccccctctgaatccccatggggcagcccgggccgaggtctatctccggaaatgc
acctttgacatgttcaacttcctggcctcccagcaccgggtgctccctgagggagccacc
tgtgacgaggaagaggatgaggtgcagctcaggtcaaccagacgtgccaccagcctggag
ctgcccatggccatgcgttttcgccacctcaagaagacatccaaagaggctgtgggtgtc
tacagatctgccatccacgggcggggcctgttctgtaagcggaacattgatgctggcgag
atggtcatcgagtattctggaatcgtcattcgctctgtgctgactgacaagcgggagaag
ttctacgatgggaaggggatcgggtgctacatgttccggatggacgacttcgatgtggtg
gacgccacaatgcacggcaatgccgcacgcttcatcaaccactcatgcgagcccaactgc
ttctcccgggtcatccacgtggagggccagaagcacatcgtcatcttcgcgttgcgccgc
atcctgcgcggggaggagctcacctatgactacaagttccccatcgaggacgccagcaac
aagctgccctgcaactgcggcgccaagcgctgccgtcgcttcctgaactga |
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