Mustela lutreola (European mink): 131819373 Help Entry 131819373         CDS       T09578                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism mlk  Mustela lutreola (European mink) Pathway mlk04072   Phospholipase D signaling pathway mlk04115   p53 signaling pathway mlk04140   Autophagy - animal mlk04150   mTOR signaling pathway mlk04151   PI3K-Akt signaling pathway mlk04152   AMPK signaling pathway mlk04211   Longevity regulating pathway mlk04218   Cellular senescence mlk04714   Thermogenesis mlk04910   Insulin signaling pathway mlk04919   Thyroid hormone signaling pathway mlk05163   Human cytomegalovirus infection mlk05165   Human papillomavirus infection mlk05168   Herpes simplex virus 1 infection mlk05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mlk00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     131819373 (TSC2)    04151 PI3K-Akt signaling pathway     131819373 (TSC2)    04152 AMPK signaling pathway     131819373 (TSC2)    04150 mTOR signaling pathway     131819373 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     131819373 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     131819373 (TSC2)    04218 Cellular senescence     131819373 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     131819373 (TSC2)    04919 Thyroid hormone signaling pathway     131819373 (TSC2)   09149 Aging    04211 Longevity regulating pathway     131819373 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     131819373 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     131819373 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     131819373 (TSC2)    05163 Human cytomegalovirus infection     131819373 (TSC2)    05165 Human papillomavirus infection     131819373 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:mlk01009]     131819373 (TSC2) Protein phosphatases and associated proteins [BR:mlk01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      131819373 (TSC2) SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP HEAT Cnd1 Motif Other DBs NCBI-GeneID:  131819373 NCBI-ProteinID:  XP_059010368 LinkDB All DBs Position 17:complement(22078734..22110964) Genome browser AA seq 1813 aa AA seqDB search MAKPTSKDSGLKEKFRNLLGLGTPRPNPRSAEGKQTEFIITADILRELSVECGINNRIRV IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDHLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAGFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYKEDAALLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI LLTIMERLLQQLQSLDSPELRAVVHDLLTTVEELCDQSEFHGSPERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELISSVVISQLSHVPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVMSRSLS PPAELEERDVAAYSASVEDVRTAVLGLLVILQTKLYSLPASHAMRVYETLVGHIQLHYKH DYTLPIAASIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCDAMEPERGPEKKAS GTLSNPTGPPGPAPTGPAVRLGSLPYSLLFRVLLQCLKQEADWKVLKLVLGKLPESLRYK VLIFTSPCSVDQLSAALCSMLSGPRTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARTPKQGLTNS PPVKECKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQGGPELSTDAGVHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLHVG TLDTPASHFAGGPTSPGAQTAPASKPERASAGTQFPAQEKTSLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSVPAAGS AKPPPPPRSNTVASLSSLCQSSCRAQLHRGVSWADSAVVPEEGSPSEARLPTEPTELEDF EATLGTDRRSSRAEAYSRSSSSSSQEERFPAEEPAAGGVPIERAVSSEGARPSAELPFQP CQPLSKSSSSPELQTLQDILGDPGDKTDVGRLSPEAKTRSQSGILDGAGAAWSAPGEESQ GRGPTQPEGPLLSSCPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKSRTGASNTEKVPG INPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSN SELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQ AVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIRGQFNFVHVIITPL DYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIY PSKWIARLRHIKRLRHRIQEEAQYSSPSLPLLQTHAPGHGKAPAPAPAEPVPAYETGQRK RLISAVDDFTEFV NT seq 5442 nt NT seq  +upstreamnt  +downstreamnt atggccaagccgacaagcaaagattcaggtctgaaggagaaattcaggaatctgttagga ctgggaaccccgaggccaaaccccaggtctgcagagggcaagcagacggagtttatcatc acagccgacatcctgagagaactgagtgtcgaatgtggtatcaacaatcgcatccgggtg atagggcagatctgcgaggttgccaaaacgaagaaatttgaagagcacgcggtggaggcg ctgtggaaggccgtggcggacctgctgcagccagagcggcccccagaggcccggcacgcg gtgctggctctgctgaaggccattgtgcaggggcagggggaccacctgggcgtgctcaga gccctcttcttcaaggtcatcaaggattacccttccaatgaagacctccacgagagactg gaagtgttcaaggccctcacggacaacgggagacacatcacctacttggaagaagaactg gctgggttcgtgctgcagtggatggacatcggcctgtcctcagaattcctcttggtgctt gtgaacttggtcaagttcaacagctgttacctggatgagtacattgcatcgatggtccac atgatctgcctgctgtgtgtccagacggtgtcgtccgtagacatagaggtgtccctgcag gtgctggacgccgtggtctgctacaactgcctgccggccgagagcctcccgctgttcatc gtcactctctgccgcaccatcaatgtcaaggagctctgtgagccttgctggaagctgatg cgtaacctcctgggcacccatctggggcacagtgccatctacaacatgtgtcggatcatg gaggacagagcctacaaggaggacgccgcgctgctgagaggcgccgtgttctttgtgggc atggcgctctggggcgcgcaccgactttactctctgaagaactccccgacatctgtgctc ccgtccttttatgaggccatgacctgtccgaacgaggtggtgtcctacgagattgtgctg tccataaccagactgatcaagaagtaccggcgggagctccaggccgtgacgtgggacatc ctgctgaccatcatggagcgcctgctgcagcagctccagagcctggacagcccagagctc agagccgtcgtccacgacctgctgaccacggtggaagagttatgcgatcagagcgagttc cacggctctccagagagatacttcgagctggttgagcgatgcgcagaccagaggcctgag tcctcgctcttgaacttaatcacgtacagggctcagtcgatccatccggccaaagacggc tggattcacaacctgcagctgctgatggagaggttcttcaggaatgagtcccgcagtgcc gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacagacagttctat gaggaggagctgatcagctcagtggtcatctcacaactctcccacgtcccagaggacaaa gacccccaagtccggaaactggccacccagctgctggtggacctggctgagggctgtcat acccaccacttcaacagcctgctggacattgtggaaaaggtgatgtcccgctccctttct ccacccgctgagctggaggagagagacgtggcggcgtactcagcctccgtggaggacgtg aggactgctgtcttggggctcctggtcatcctgcagaccaagctatactccttgcccgcc agccacgcgatgcgcgtttacgagacacttgttggccacattcagctgcactacaagcac gactacaccctgcccattgccgccagcatccggctacaggccttcgacttcctgctgctc ctgagggccgactcgctgcaccgtctcggcctgcccagcaaggatggggccgtgaggttc agcccttactgtgtttgcgatgccatggagccagagcggggtccagagaagaaggccagt ggcaccctgtccaatcccactgggccgcccggccctgcgcccacaggccccgcggtgaga cttggctctttgccttactccctgctcttccgtgtgctgctgcagtgcctgaagcaggag gcggactggaaggtactgaagctcgtgttgggcaagctgcccgagtccctgcgttacaag gtgctcatcttcacgtctccgtgcagcgttgaccagctgtccgctgccctctgctccatg ctttcaggtcccaggaccctggagcggctccgaggcaccccggaaggcttctccagaacc gacctgcatctggcagtggttcccgtgctgacagcactcatctcgtaccacaactacttg gacaaaaccagacagcgggagatggtgtactgcctggagcaaggcctcatctaccgctgt gccagccagtgcgtggtggcactggccatctgcagcgtggagatgccggacatcatcatc aaggcgcttcctgtgctggttgtgaagctcactcacatctcagccactgctagcatggcc gttcctctccttgagttcctgtcaactctggccaggctgcctcacctctacaggaacttt gcagcggagcagtacgcgagtgtctttgccatctccttgccttacaccaatccctccaag tttaatcagtacatcgtgtgcctggcccatcacgtcatagccatgtggttcattagatgc cgcctgcccttccggaaggattttgttccctttatcactaagggcctgcgctccaacgtt ctcctgtcctttgatgacacccccgagaaggacagcttcagagcgcgaagcaccagcctc aacgagaggcccaagagtttgaggatagccagaacccccaaacaaggcttgactaactct ccacccgtgaaagaatgcaaggagagctctgccgcagaggccttccggtgccgcagcatc agtgtgtcagagcatgtggtccgcagcaggatccagacgtccctcaccagcgccagtctg gggtctgcagacgagaattcaatggcccaggctgatgacaacttgaaaaatctccacctg gagctcacggagacatgtctggacatgatggccagatacgtgttctccaacttcacagcg gtccccaagaggtcccctgtgggagagttcctcctggctggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcaccgtgacaacgagtgtgggaaccgggacccggtcgctg ctgggtttggactcaggagagctgcagggaggcccagagttgagcactgacgctggtgtg cacgtgagacagaccaaggaggcgcctgccaagctagagtcccaggctgggcagcaggtg tgccgcggggccagggatcgcgtccgctccatgtccgggggccatggccttcatgtgggt accctggacactccagcatcccacttcgcaggtggccccacttctcctggtgcacagacg gcaccagccagcaaacctgagagggcgtcagcgggcacccagttcccagcacaggagaag acgagcctggcggcctacgtgccccttctgacccagggctgggcagagatcctggtccgg aggcccacagggaacaccagttggctgatgagcctggaaaaccctctgagccccttctcc tcggacatcaacaacatgccgctgcaggagctgtccaatgcgctcatggccgctgagcgc ttcaaggagcgtcgggacacggccttgtacaagtcactgtcggtgccggcggctggctcg gccaagccccctccacccccgcgatccaacacggtggcctctctctcctcgctgtgccag tccagttgccgagcacagctgcacaggggcgtttcctgggcagactcagcggtcgttccg gaggaggggagtccgagcgaggctcgtttgcccactgaacccacagagttggaggacttt gaggcaacgctaggcacagaccggcgcagcagccgcgctgaggcttacagcaggtcatca tcaagctccagccaggaggagaggttccccgcggaggagcctgctgctggaggagtcccc atcgagcgggctgtctcttccgagggcgcccggccttctgcggagctccccttccagccc tgccagcccctcagcaagtccagctcctcgcccgagctgcagaccctacaggacatcctt ggggaccctggggacaagactgatgttggccggctgagccctgaggccaagacccggtcc cagtccgggatcctggacggggcaggtgccgcctggtcagccccaggtgaagagagccag ggccggggccccacgcagcccgagggtcccttgctttccagctgcccccgctcccccagt ggcctgcggcccagaggctacaccatctctgattcggccccgtcacgcagaggcaagagg gtagagagggatgccttcaagagcagaactggggcctccaataccgagaaggtacccggc atcaatcccagctttgtgttcctgcagctctaccattccccgttctttggtgacgaatcc aacaagcccatccttctccccaatgagtccttcgagcggtcagtgcagcttctcgaccag attccgtcctacgacacccacaagatcgccgtcctgtacgtgggagaaggccagagcaac agcgagctcgccatcttgtccaacgagcacggctcctacaggtacacggagttcctcacc ggcctgggcaaactcatcgagctcaaggactgtcagccagacaaggtgtacctgggcggc ctggatgtatgcggggaggacggccagttcacttactgctggcatgacgatatcatgcaa gcggtcttccacattgccactctgatgcccaccaaagatgtggacaagcaccgctgtgac aagaagcgccacctgggcaacgacttcgtgtccatcgtctacaatgactcgggcgaggac ttcaagctgggtaccatcagaggccagttcaactttgtccacgtgatcatcacccccctg gactacgaatgcaatctggtgtccctgcagtgcaggaaagacatggagggcctcgtggac accagcgtggccaagatcgtgtctgaccgcaacctgccttttgtggcccgtcagatggct ctgcacgcaaacatggcctcacaggtgcatcacagccgctccaaccccaccgacatctac ccctccaagtggattgccaggctccgtcacatcaagcgactccgccaccggatccaagag gaagcccagtactccagccctagcctgcccctgctgcagacgcacgccccgggccacggc aaagcacccgctccggcgcccgcggagcccgtgccggcgtacgagaccggccagcggaag cgcctcatctccgcggtggatgacttcacagagttcgtgtga

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