KEGG   Mustela lutreola (European mink): 131820095
Entry
131820095         CDS       T09578                                 
Symbol
SMURF1
Name
(RefSeq) E3 ubiquitin-protein ligase SMURF1 isoform X1
  KO
K04678  E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
Organism
mlk  Mustela lutreola (European mink)
Pathway
mlk04120  Ubiquitin mediated proteolysis
mlk04137  Mitophagy - animal
mlk04144  Endocytosis
mlk04340  Hedgehog signaling pathway
mlk04350  TGF-beta signaling pathway
mlk04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:mlk00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    131820095 (SMURF1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    131820095 (SMURF1)
   04350 TGF-beta signaling pathway
    131820095 (SMURF1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    131820095 (SMURF1)
   04137 Mitophagy - animal
    131820095 (SMURF1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    131820095 (SMURF1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mlk04131]
    131820095 (SMURF1)
   04121 Ubiquitin system [BR:mlk04121]
    131820095 (SMURF1)
   03029 Mitochondrial biogenesis [BR:mlk03029]
    131820095 (SMURF1)
Enzymes [BR:mlk01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     131820095 (SMURF1)
Membrane trafficking [BR:mlk04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    131820095 (SMURF1)
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    131820095 (SMURF1)
Ubiquitin system [BR:mlk04121]
 Ubiquitin ligases (E3)
  HECT type E3
   131820095 (SMURF1)
Mitochondrial biogenesis [BR:mlk03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    131820095 (SMURF1)
SSDB
Motif
Pfam: HECT WW C2 DUF7350
Other DBs
NCBI-GeneID: 131820095
NCBI-ProteinID: XP_059011612
LinkDB
Position
17:complement(39745890..39852474)
AA seq 731 aa
MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDP
KWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCK
LNPSDTDAVRGQIVVSLQTRDRIGTGGSVVDCRGLLENEGTVYEDSGPGRPLSCFMEEPA
PYTDSTAAAAGGGDCRFVESPSQDQRLQAQRLRNPEVRGSLQTPQNRPHGHQSPELPEGY
EQRTTVQGQVYFLHTQTGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVD
HNNRTTQFTDPRLHHIMNHQCQLKEPSQPLPLPSEGSVEDEELPAQRYERDLVQKLKVLR
HELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVARE
WLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYI
NGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRIL
QHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQK
ELELIIGGLDKIDVSDWKSNTRLKHCGADSNIVRWFWQAVETFDEERRARLLQFVTGSTR
VPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLT
AVEETCGFAVE
NT seq 2196 nt   +upstreamnt  +downstreamnt
atgtcgaaccccgggacgcgcaggaacggctccagcatcaagatccgtctgacagtatta
tgtgccaagaaccttgcaaagaaagacttcttcagactccccgacccctttgcaaagatt
gtggtggacggatctgggcagtgccactcaacggacactgtgaaaaacacgttggacccc
aagtggaaccagcactatgatctgtatgtcggcaaaacggattccataaccatcagcgtg
tggaaccacaagaaaatccacaagaagcagggggctggctttctgggctgcgtgcggctg
ctctccaacgccatcagccgattaaaagataccggataccagcgtttggatctatgcaaa
ctaaacccctcagatactgatgcagttcgtggccaaatagtggtcagtttacagacacgg
gacaggataggcactggaggctccgtggtggactgcaggggactgttagagaacgaagga
accgtgtatgaagactcggggcccgggaggccactcagctgcttcatggaggagccggcc
ccgtacacagacagcaccgctgctgctgcggggggaggggactgcaggttcgtggagtcc
ccgagtcaagatcagagactccaggcgcagcgactccgaaatcccgaggtccgggggtct
ctccagacgcctcagaaccgaccccacggccaccagtcaccagaactgcccgaaggctat
gaacaaaggacaacggtgcagggccaagtttactttttgcacacacagactggagtcagc
acgtggcacgaccccaggataccaagagaccttaacagtgtgaattgtgatgaacttgga
ccactgccaccaggttgggaagtccgaagtacggtttcggggagaatatattttgtagat
cataataaccgaacaacccagtttacagacccaagattacatcacatcatgaatcaccag
tgccagctaaaggagcccagccagccgctgccattgcctagcgagggctctgtggaagac
gaggagcttcccgcccagagatacgaaagagatttagtccagaagctgaaggtcctcaga
cacgaactttcactgcagcaaccccaggcgggtcactgccgcatcgaagtatccagagaa
gaaatatttgaggagtcttaccgtcagatcatgaagatgcggcccaaggatctgaagaag
cggctgatggtgaagttccggggagaggaaggtctggattatggcggagtggcgagggag
tggctttacttactgtgccatgaaatgttgaatccatattacggactcttccaatattct
acggacaacatttacatgttgcagatcaacccagattcctcaatcaaccccgaccatcta
tcttacttccactttgtgggccggatcatgggtctcgctgtgttccacggacactacatc
aacggaggcttcacggttcccttctataagcagctcctggggaagcccatccagctctca
gatttggagtcggtggatccagaattacataagagcctagtgtggattctagagaacgat
atcacccccgtgctggaccacaccttctgcgtggagcacaatgccttcgggaggattctt
cagcatgaactgaagcccaacggccgaaacgttcctgtcacagaggagaacaagaaagaa
tatgtccggttgtacgtaaactggagattcatgagggggatcgaagcccagttcttagct
ctccagaaaggatttaatgaactcattcctcaacacttactaaagcctttcgaccagaag
gaactggagctgatcatcggcggcctggataagatcgacgtgagcgactggaagtccaac
acgcggctgaagcactgcggggccgacagcaacatcgtccgctggttctggcaggcggtg
gagaccttcgacgaggagaggagggccaggctcctgcagttcgtgacggggtccacccgg
gtccctctccaaggcttcaaggctttgcaaggctctacaggcgcggcagggccccggctc
ttcaccatccacctcatcgacgccaacacagacaacctcccgaaggcccatacctgcttt
aatcggattgacatcccaccgtatgaatcctatgagaagctctatgagaagctgctgacg
gctgtggaggagacgtgtggctttgctgtggagtga

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