KEGG   Mustela lutreola (European mink): 131820779
Entry
131820779         CDS       T09578                                 
Symbol
ATP7A
Name
(RefSeq) copper-transporting ATPase 1 isoform X1
  KO
K17686  P-type Cu+ transporter [EC:7.2.2.8]
Organism
mlk  Mustela lutreola (European mink)
Pathway
mlk01524  Platinum drug resistance
mlk04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:mlk00001]
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    131820779 (ATP7A)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    131820779 (ATP7A)
Enzymes [BR:mlk01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.8  P-type Cu+ transporter
     131820779 (ATP7A)
SSDB
Motif
Pfam: HMA E1-E2_ATPase Hydrolase HMA_PCA1 Hydrolase_3 Hydrolase_6
Other DBs
NCBI-GeneID: 131820779
NCBI-ProteinID: XP_059012490
LinkDB
Position
X:68050998..68238572
AA seq 1508 aa
MKECKEEIKMDRSMRVDSVTISVEGMTCSSCVWTIEQRIGKLKGVHHIKVSLEEKNATII
YDPKLHTPKTLLEAIDDMGFDAILHNPNPLPVLTETVFLTVAASLAVPWDHIQNTLLKTK
GVTDIKIYPQERTVVVTVIPSIVNANQIIELLPDLSLDTGTLEKKSGTCEDYSLAQAGEV
MLKMKIEGMSCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLITVEEIKNQIEA
VGFPAFIKKQPKYLKLGAIDIERLKNTPVKSSEGSQQRSPSYTSDSTVTFLIDGMHCKSC
VLNIESTLSTLQYVSSVIVSLEKRSAIVKYNASSVTPETLRKAIEAVLPGQYRVSITSEV
ESISNSPSSSSLQKIPLNVASHPLTQQTVINIDGMTCNSCVQSIESVILKKAGVKSIQVS
LANGNGTVEYDPLLTTPEALREAIEDMGFDAALSDTNEPFVIIAQTSSEMPLLTSTNEFY
TKMMTPINDAEAKTTSKCYIQVTGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRY
NPAVIQPPMIAEFIRELGFGATMIENADEGDGVLELVVRGMTCASCVHKIESTLTKHRGI
FYCSVALATNKAHIKYDPEIIGPRDIIHRVESLGFEASLVKKDRSASHLDHKREIRQWRR
SFLVSLFFCIPVMGLMIYMMAMDHHLATLHHNKNMSQEEMIKIHSSMFLERQILPGLSIM
NLLSFLLCVPVQFFGGWYFYIQAYKALRHKTANMDVLIVLATTIAFAYSLVILLVAMYER
AKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLDSDNILL
SEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKSGSTVIAG
SINQNGSLLIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVIVSIAT
LFVWIVIGFLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAV
MVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVESNKISRSK
ILAIVGTAESNSEHPLGTAITKYCKQELDIETLGTCVDFQVVPGCGISCKVINIEALLHK
NNWKIEENNIKNASLVQIGASNEQSSTSSSMIIDAQLSSALNAQQYKVLIGNREWMIRNG
LVINNDVDDYMTEHERKGRTAVLVAVDDELCGLIAIADTVKPEAELAVRILQYMGLEVVL
MTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA
NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFIFALIYNLVGIPI
AAGVFMPIGLVLQPWMGSAAMAASSVSVVLSSLLLKLYRKPTYENYELHARSQMGQKRPS
EISVHVGIDDTLRNSPKLGLLDRLVNYSRASINSLLSDKRSLNSIGTSEPDKHSLLVGDS
REDDDTAL
NT seq 4527 nt   +upstreamnt  +downstreamnt
atgaaggaatgtaaagaagaaatcaagatggatcgaagtatgcgtgtggattcagtcacc
atctctgttgagggaatgacatgtagttcctgtgtttggaccattgagcagcggattgga
aaactgaagggtgtacatcatattaaagtttccctggaagaaaaaaatgcaactattata
tatgaccctaaactacacactccaaagaccctactggaagctattgatgacatgggcttt
gatgctattctccacaatcctaatcctctccctgttttaactgagactgtgtttctgact
gttgctgcttcactggctgtgccatgggaccatatccaaaacacattgctcaagaccaag
ggtgtgacagacattaaaatttaccctcaggaaagaactgtagtggtgacggtaatccct
tctatagtgaatgccaatcagataatagagctccttccagatctcagtttagatactgga
actctggagaaaaagtcaggaacttgtgaagattacagtctggctcaagcaggtgaagtc
atgctgaagatgaaaatagaagggatgtcttgccattcatgcaccagcaccattgaaggg
aaaattgggaagctgcaaggtgttcagcgaattaaagtttccctggacaaccaagaagct
actattgtttatcagcctcatcttatcacagtagaggaaataaaaaatcagattgaagct
gtgggctttccagcattcatcaaaaaacagcccaagtacctcaaattgggggctattgat
atagaacgcctaaagaacacaccagtcaaatcctcagaaggatcacagcaaaggagtcca
tcatataccagtgattcaacagtcactttccttatagatggcatgcattgtaaatcatgt
gtattaaatattgaaagtactttatctacactccagtatgtaagcagcgtcatagtttct
ttagagaagagatctgccatcgtaaagtacaatgcaagctcagtcactccagaaaccctc
agaaaagcaatagaagccgtgttaccagggcaatatagagttagtattacaagtgaagtt
gagagtatctcaaactctccctctagctcatctcttcaaaagatccctttgaacgtagct
agccatccgctgactcaacaaactgtgataaacattgatggcatgacttgtaattcttgt
gttcagtctattgagagtgtcatattaaaaaaggcaggtgtaaaatccatacaagtatct
cttgcaaatggcaatgggactgttgagtatgatcctctactaaccactccagaagccttg
agagaagcaatagaagacatgggatttgatgctgccttgtcagatacaaatgagccattt
gtaataatagctcagacctcatcggaaatgccgcttttgacctcaacgaatgaattttat
actaaaatgatgacaccaattaatgacgcggaagcaaagactacatctaagtgttacata
caggtcactggtatgacttgtgcttcctgtgtagcaaacattgaacggaatttaagacga
gaagaaggaatatattctgtacttgtggctctgatggctggcaaggcagaagtaagatat
aatcctgctgttatacaaccaccaatgatagctgagttcatccgagagcttggatttgga
gccactatgatagaaaatgctgatgaaggagatggtgttttggaacttgttgtgagagga
atgacatgtgcctcctgtgtacataaaatagagtctaccctcacaaaacacagagggatc
ttctattgctctgtggccctggcaaccaacaaagcacatattaaatatgacccggaaatt
attggtccccgggatattatccatagagttgaaagcttaggttttgaagcttctttggtc
aagaaggatcgatcagcaagccacctggaccataaacgagaaataagacagtggagacgc
tccttccttgtgagcctctttttctgtattcctgtaatggggctgatgatatatatgatg
gctatggatcaccatcttgcaactcttcaccataataagaacatgagccaagaagaaatg
atcaaaattcattcttctatgttcctggagcgccagatcttgccaggactgtccattatg
aatttgctatcctttctattgtgtgtacctgtacagttttttggaggctggtacttctac
attcaggcctacaaagcactgaggcataaaactgcaaatatggatgtactgattgtgctg
gcgaccacaatcgcatttgcctactctctggttattcttctggttgcaatgtatgaaaga
gccaaagtaaaccctataactttctttgatacgcctcctatgctatttgtatttattgcc
ctgggccggtggctggaacatatagcaaagggcaaaacatcagaggctcttgccaagcta
atttcactacaagctacggaagcaactattgtaactcttgactctgataatattctctta
agtgaagaacaagtggatgtggaacttgtacaacgcggagacatcattaaagttgttcca
ggaggcaaatttccagtggatggtcgtgttattgaaggccattctatggtagatgagtcc
cttatcacaggggaggcaatgcctgtggctaagaaatctggcagcacagtaatcgctggt
tccattaaccagaatgggtcgctgcttatccgtgcaacccatgttggagctgatacaaca
ctttctcaaattgtcaaacttgtggaagaggcgcaaacatcaaaggctcctatccaacag
tttgcagacaaactcagtggctactttgttccttttattgttattgtttccattgctact
ctcttcgtttggattgtaattggatttctgaatttcgaaattgtggaaacctactttcct
ggatataacagaagtatctcccgaacagaaacgataatacgctttgctttccaagcctct
atcacagttctgtgcattgcatgcccctgttcactgggactagccactccaactgccgtg
atggtgggtacaggagtaggagctcaaaatggcatactaatcaaaggtggcgagccactg
gagatggctcataaggtgaaggtagtggtgtttgataagactggaacgattacccatgga
accccagtagtaaatcaagtaaaggttttagtggaaagtaacaaaatatcacgcagtaag
atcctggccatcgtgggaactgctgaaagtaacagtgaacatcctcttggaacagccata
accaaatactgcaagcaggagctggacattgagaccttgggtacctgcgtagatttccag
gttgtgccaggctgtggtattagctgtaaagtcatcaatatcgaagccttgctacataag
aataactggaagatagaggaaaataatattaaaaatgcatccctggttcaaattggtgca
agtaatgaacagtcatcaacttcatcttccatgattattgatgcccagctctcaagtgct
cttaatgcccagcagtacaaagtcctcattggtaaccgggagtggatgattagaaatggt
cttgttattaataatgatgtagatgattacatgactgagcatgaaagaaaaggtcggact
gccgtattggtggcagttgatgatgagctgtgcggcttgatagctattgctgatacagtg
aagccggaagcagaattggctgtccgtattttgcagtatatgggcttagaagtagttctg
atgactggagacaacagtaaaacagctcgatctattgcttctcaggttggcattacaaag
gtgttcgctgaagttctcccttctcataaggttgctaaggtgaagcaacttcaggaggag
gggaaacgggttgcaatggtaggagatggaatcaatgactctccagctctggcaatggct
aatgttgggattgccattggcacaggtacagatgtagccattgaagcagctgatgtggtt
ttgataaggaatgatcttctggatgtagtggcaagtattgacttatcaaggaagacagtg
aagaggattcggataaattttatttttgctctgatttataatctagttggaattcccata
gctgctggagtgtttatgcccattggtttggttttgcagccctggatgggatctgctgca
atggctgcttcatctgtttcagtagtactctcctctctcttacttaaactttacagaaaa
ccaacttatgagaattacgaactgcatgcccgaagccagatgggacagaagaggccttca
gagatcagcgttcatgttggaatagatgacaccttgagaaactcccctaaactgggtttg
ctggaccggcttgttaattacagcagagcctccataaattcactgctgtctgataaacgg
tccctcaacagcattggtaccagtgaacctgataagcattcacttctggtgggagacagt
agggaagatgatgacaccgcattgtaa

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