Mustela lutreola (European mink): 131823516
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Entry
131823516 CDS
T09578
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk04217
Necroptosis
mlk04380
Osteoclast differentiation
mlk04620
Toll-like receptor signaling pathway
mlk04621
NOD-like receptor signaling pathway
mlk04630
JAK-STAT signaling pathway
mlk04658
Th1 and Th2 cell differentiation
mlk04659
Th17 cell differentiation
mlk05145
Toxoplasmosis
mlk05160
Hepatitis C
mlk05161
Hepatitis B
mlk05162
Measles
mlk05164
Influenza A
mlk05165
Human papillomavirus infection
mlk05167
Kaposi sarcoma-associated herpesvirus infection
mlk05168
Herpes simplex virus 1 infection
mlk05169
Epstein-Barr virus infection
mlk05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
131823516 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
131823516 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
131823516 (TYK2)
04621 NOD-like receptor signaling pathway
131823516 (TYK2)
04658 Th1 and Th2 cell differentiation
131823516 (TYK2)
04659 Th17 cell differentiation
131823516 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
131823516 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
131823516 (TYK2)
05160 Hepatitis C
131823516 (TYK2)
05171 Coronavirus disease - COVID-19
131823516 (TYK2)
05164 Influenza A
131823516 (TYK2)
05162 Measles
131823516 (TYK2)
05168 Herpes simplex virus 1 infection
131823516 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
131823516 (TYK2)
05169 Epstein-Barr virus infection
131823516 (TYK2)
05165 Human papillomavirus infection
131823516 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
131823516 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlk01001
]
131823516 (TYK2)
Enzymes [BR:
mlk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
131823516 (TYK2)
Protein kinases [BR:
mlk01001
]
Non-receptor tyrosine kinases
JAK family [OT]
131823516 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
RA_2
FERM_C_FAK1
Kdo
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
131823516
NCBI-ProteinID:
XP_059015922
LinkDB
All DBs
Position
2:complement(7674451..7693654)
Genome browser
AA seq
1218 aa
AA seq
DB search
MSLCHWGATTRDSRPDGNGAQPMATRGGLKVLLHWAGPGGGDPWVTFSEATLTAEEVCIH
IAQKVGITPSCLNLFALFDAQAQVWLPPNHVLEIPRDMSLTLYFRMRFYFRNWHGTNPQE
PAVYRCGPPGPKSSSEQAEQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSGEEEIRHF
KNESLGMAFLHLCHLALCRGVPLEKVAKKIRCLGMRRERVSGSRKRPRLLCFKDCIPRSF
RLQIRRHNALTRLRLRNIFRRFVRAFQPGHVSQQVVMVKYLATLEQLAPRFGTERLPVCH
LELLAQAVGEPYYLRDAGQAPPEPGPELATGPPTHEVLVTGTGGIQWRPVRAEDPRGDGS
SRNPCAGPSGKGTKAPAAGDQPADRPQEALWTYFCDFQDITHVVLKECHVSVHSQDNKSL
ELTLPSRAMALSLVSLVDGYFRLTADSSHYLCREVAPPRLVMSIQDGIHGPLLEPFVLAK
LRPEDGLYLIHWSTSHLNRLILTVAQREQAPGTQHVHLRKFPIELQAGVFTLEGWDRSFP
SVRELRAALQGCCLRAGNDCFALRRCCLPRPGEISNLIIMRGSRASAAPPNLSQLSFHRI
SQDDITQLSHLGQGTRTNVYEGILRVGGRDPKEGTADSEDPPTPSGDCGQELRVVLKVLD
PSHHDIALAFYETASLMSQVSHVHLAFVHGICVHGSERSGRQVGGLCSAWDFADIMVAEY
VEHGPLDVWLRREKGHVPVAWKVVVAQQLASALSYLEDKSLVHGNVCGRNILLARLGLTE
GTSPFIKLSDPGVGLGALSREERVERIPWTAPECLSGGANSLTTAADKWGFGATLLEICF
DGEAPLQGRGPSEKECFYQKQHQLPQPSCPELATLTSQCLTYEPAQRPSFRTILRDLTQL
QPQNLADVLAVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV
KTLKADCGPQLRTSWRREIDILRTLYHKHIVKYKGCCEDAGEKAVPLVMEYVPLGSLRDY
LPRHSVGLAQLLLFAQQICEGMAYLHAQHYVHRDLAARNVLLDNDRLVKIGDFGLAKAVP
EGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTMYELLTYCDSSQSPPSKFM
ELIGLTHGQMTVLRLTELLERGERLPRPERCPCEIYLLMKNCWQAEASFRPTFQNLIPIL
KTIQEKYQGQAASVFNVC
NT seq
3657 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgtgccactggggtgccaccaccagggacagcaggcctgatggcaatggagct
cagcccatggccaccaggggaggcctgaaggtccttctgcactgggctggccctggcggc
ggggacccctgggtcaccttcagcgaggccacactgaccgcagaggaggtctgcatccac
attgcacaaaaagtcggcatcactccatcctgcctcaatctctttgccctcttcgatgcc
caggcccaggtctggctgcccccaaaccatgtcttggagatccccagagacatgagcctc
acgctgtacttccgcatgaggttttatttccggaactggcatggcacaaacccccaggag
ccagctgtgtaccgctgtgggcccccagggcccaagtcttcctctgaacaggcagagcag
ggcatgcaactactggacccggcctcctttgagtacctctttgagcagggcaagcatgag
tttgtgaatgacgtagcatcgctgtgggagctgtctggcgaggaggagatccgccatttt
aagaatgagagtctgggcatggcctttctgcacctgtgccaccttgccctgtgccgtggc
gtccccctggagaaggtggccaagaagatcaggtgtctgggaatgcggcgggaacgggta
tctgggagccgcaagagacctcgcctactgtgcttcaaggactgcatcccacgctccttc
cggctgcagatccggcggcacaatgcgctgacccgactgcgcctgcggaacatcttccgc
aggttcgtgcgggccttccagccgggccacgtctcacagcaggtcgtcatggtcaaatac
ctggccacgctcgagcagctggcaccccgcttcggcacggagcgcctgcccgtgtgccac
ctggagttactggcccaggccgtgggggagccctactacctccgggacgccgggcaggct
cccccagagcctgggccggagttggccaccgggccacccactcacgaggtgctggtgacg
ggcacaggtggcatccagtggcggccggtgcgggcagaggatcccagaggcgatggcagc
agcaggaatccctgtgctggcccatctgggaagggaaccaaggccccagcagcaggcgac
cagccagcagacaggcctcaggaagcgctgtggacctacttctgtgacttccaggacatc
acacacgtggtgctgaaggaatgccacgtcagcgtccactctcaggacaacaagagcctg
gagctgaccctgccttcccgggccatggccctgtccttggtgtcactggtggacggctat
ttccgcctgaccgcagactcaagccactacctgtgccgcgaggtggcgccgccacggctg
gtgatgagcatccaggacgggatccacggacccctgctggagccatttgtgctggccaag
ttgcggcccgaggacggcctctacctcatccactggagcaccagccacctcaaccgcctc
atcctcacggtggcgcagagagagcaagccccaggcacacagcacgtgcacctgcgcaaa
ttccccattgagctgcaggccggggtcttcacgctggagggctgggaccggtccttcccc
agcgtgcgggagctgcgagctgccctgcagggttgctgtctgcgggctggcaacgactgc
ttcgccctgcgccgctgttgcctgccacggcctggagagatctccaacctcatcatcatg
cgggggtctcgggccagcgccgctccgcccaacctcagccagctcagcttccaccggatc
agccaggatgacatcacccagctgtcccacttgggccaaggcaccaggaccaacgtgtac
gagggcatcttacgagtggggggcagagaccccaaggagggcacggcagacagtgaggac
ccccccacacccagtggggactgcgggcaagagctccgggtggtcctcaaggtgctggac
cccagtcaccacgacatcgcgctggccttctacgagacagccagtctcatgagccaggtc
tcccacgtgcacctggcctttgtacatggcatctgcgtgcatggctccgagagaagtggg
aggcaggtgggcggcctgtgcagtgcctgggactttgcagacatcatggtggcagagtac
gtggagcacgggcccctggacgtgtggctgcggcgagagaagggccacgtgcctgtggcc
tggaaggtggtggtggcccagcagctggccagcgccctcagctacctggaagacaagagc
ctggttcatggtaatgtgtgtggccggaacatcctgttggcacggctagggctgacggag
ggcaccagccccttcatcaagctgagtgaccccggtgtgggcctgggtgccctttccagg
gaggagcgggtggagcggatcccctggacagcccctgagtgcctctccggcggagccaac
agtctgaccactgcggctgataaatggggctttggtgccaccctcctggagatctgcttc
gatggggaggcccctctgcagggccgtggcccctccgagaaagagtgcttctaccaaaag
cagcaccagcttcctcagccctcctgcccggagctggccacactcaccagccagtgcctg
acttacgaaccagctcagcggccctccttccgcactatcctgcgggacctcactcagctg
cagccccagaatcttgctgacgtcttggctgtgaaccctgactcacctgcgtcagacccc
accgtgttccacaagcgctatttgaaaaagatccgagatctgggcgagggccatttcggc
aaggtcagtctgtactgctacgaccccacgaacgacggcaccggcgagatggtggccgtg
aagaccctcaaggcggactgcggcccccagctccgcaccagctggcggcgggagatcgac
atcctgcgcacgctgtaccacaagcacattgtcaagtacaagggctgctgcgaggacgca
ggagagaaggcggtaccgctggtcatggagtatgtgcccctgggaagcctgcgggactac
ctgccccggcacagcgtggggctggcgcagctgctgctcttcgcccagcagatctgtgag
ggcatggcctacctccatgcacagcactacgtgcaccgagacctggcggcccgcaacgtg
ctgctggacaacgacaggctggtcaaaatcggggactttggtctagccaaggctgtgccc
gaaggccatgagtactaccgcgtgcgcgaggatggggacagccccgtattctggtatgcc
ccagagtgcctgaaggagtgtaagttctactatgcctctgatgtctggtccttcggggtc
accatgtacgagctgctgacctactgtgactccagccagagccccccctcgaaattcatg
gagctcataggcctcacccatgggcagatgacggtgctgaggctcactgagctgctggaa
cgcggggagaggctgccccggccggagagatgtccttgtgagatctatctcctcatgaag
aactgctggcaggcggaggcctcattccgccccaccttccagaacctcatacccattctc
aagaccatccaggagaaataccaaggccaggctgcctcagtgttcaatgtgtgctga
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integrated database retrieval system
