Mustela lutreola (European mink): 131823518
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Entry
131823518 CDS
T09578
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk00230
Purine metabolism
mlk01100
Metabolic pathways
mlk04024
cAMP signaling pathway
mlk04928
Parathyroid hormone synthesis, secretion and action
mlk05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
131823518 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
131823518 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
131823518 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
131823518 (PDE4A)
Enzymes [BR:
mlk01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
131823518 (PDE4A)
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Ortholog
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GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
131823518
NCBI-ProteinID:
XP_059015930
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All DBs
Position
2:7718408..7763410
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AA seq
871 aa
AA seq
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MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERS
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCRRFEAENGPSPSPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
SSPTMKDREKQPAPRQRPSQQPPPPGTQFQPMSQITGVKKLRHSSSLNDSSIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYML
TLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPDEEPRGPGHPPPPDKFQFELTLEEEEEEE
VSTAPGAFEVRDLTMAQDPSPAEEPWEVDGHVLPTEVKVEEPGVTQQGDTAHSVATGEDG
AMSPDASVEAGGRSSPLALSTESPPLPSLRTPPSPEEAPGLQGLPSVAAEVGAQKEHQAA
KRACSACTGTSGEEPTPLPAPGGWGSAGGPT
NT seq
2616 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccggccgccccctcggagagaagcctgtctctgtctctgcccgggccccgg
gagggccaggccaccctgaagccgcccccccagcacctgtggcggcagccgcggaccccc
attcgtatccagcagcgcggctactccgacagcgcggagcgcgcagagcccgagcggtcg
ccacaccggcccatagagcgcgccgacgccgtggacaccggcgaccggcccggcctgcgc
acttcccgcatgtcctggccctcgtccttccacggtaccggcaccggcagcggcggcgcg
agcggaggcagctgcaggcgctttgaggcagagaatgggccctcgccgtctcccggccgc
agccccctggactcgcaggcgagcccgggcctcgtgctgcatgctggggccgccaccagc
cagcgccgggagtccttcctgtaccgctcagacagcgactacgacatgtcccccaaaact
atgtcccggaactcgtcggtcaccagcgaggcgcacgctgaggacctcattgtgacacct
tttgcccaggtgctggccagtctccggagtgttcgcagcaacttctcactcctgaccaat
gtacccattcccagcaacaaacggtccccattgggcggcccaaccccagtctgcaaggcc
acactatcagaagagacatgtcagcaactggcccgggagacactggaggagctggactgg
tgtctcgaacagctggagaccatgcagacataccgctccgtgagcgagatggcttctcac
aagttcaagaggatgttaaaccgagaactcacacacctgtcagagatgagcaggtcagga
aaccaggtctctgagtacatctccaccacattcctggacaagcagaatgaagtggagatc
tcatcgcccacaatgaaggatcgagaaaaacagccagccccacggcagagaccctcccag
cagcccccgccccccgggacacagttccagcccatgtctcagatcacaggggtgaagaag
ttgagacacagcagcagcctgaatgattccagcatcccccgctttggggtaaagaccgac
caagaggagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttt
tgcgtgtcggaatacgcgggcggccgctccctcagctgcatcatgtacacgatatttcag
gagcgggacttgctaaagaagtttcgcatcccagtggacaccatggtgacctacatgctg
accctggaggaccactaccaccccgacgtggcctaccacaacagcctgcacgcggctgat
gtgctgcagtccacacacgtgctgctggccacgcccgcgctcgatgctgtgttcacggac
ctggagattcttgccgccctctttgcagctgccattcatgacgtggaccaccctggggtc
tccaaccagttcctcatcaacaccaattcggagctggcgctcatgtacaacgacgagtcg
gtgctggagaaccaccacctggccgtgggcttcaagctgctgcaggaagagaactgcgac
atcttccagaatctcagcaagcgccagcggcagagcctgcgcaagatggtcatcgacatg
gtgctggccacggacatgtccaaacacatgaccctcctggctgacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggtgtcctcctgctggacaactactccgaccgcatc
caggtccttcgcaacatggtgcactgtgccgacctcagcaaccccaccaaaccactggag
ctgtaccgacagtggacggaccgcatcatggccgagttcttccagcagggggaccgggag
cgggagcggggcatggagatcagccctatgtgtgacaagcacacagcctcggtggagaag
tctcaggtgggtttcattgactatattgtacacccgctgtgggagacgtgggctgacctg
gtccacccagatgcgcaggagatcctggacacgttggaggacaatcgggactggtactac
agcgccattcggcagagcccttccccgccacctgacgaggagcccagagggccaggccac
ccacccccaccggacaagttccagtttgagctgactctggaggaggaagaggaagaggag
gtgtctaccgccccaggtgcatttgaagttcgggacttgaccatggctcaggatccatcc
ccggctgaggaaccgtgggaggtggatggccacgtcctgcccacagaggtgaaggtagag
gaacctggcgtcacacagcaaggcgacacagcacatagtgtggctacgggcgaggacggg
gccatgtccccagacgcatccgtggaggctgggggccgcagcagccccctggccctgtcc
actgagagcccccctctgccttccttgaggaccccaccctctccagaggaagccccgggc
ctccagggcctcccctccgtggcggccgaggtgggggcccaaaaagagcaccaggctgcc
aagagggcgtgcagtgcctgcacgggaacatctggcgaggagcccaccccactcccagct
cctggtgggtgggggtcagctggaggtcctacctga
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