| Entry |
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| Symbol |
ABCC2
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| Name |
(RefSeq) ATP-binding cassette sub-family C member 2 isoform X1
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| KO |
| K05666 | ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
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| Organism |
mlk Mustela lutreola (European mink)
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| Pathway |
| mlk04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:mlk00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
131828556 (ABCC2)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
131828556 (ABCC2)
04981 Folate transport and metabolism
131828556 (ABCC2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
131828556 (ABCC2)
01523 Antifolate resistance
131828556 (ABCC2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:mlk02000]
131828556 (ABCC2)
Transporters [BR:mlk02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
131828556 (ABCC2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
4:complement(28412107..28485442)
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| AA seq |
1544 aa
MLEKFCNSTFWNSSFLDSPEADLPLCFEQTVLVWIPLGFLWLLAPWQLLHVYRSKIKRSP
ITKLYLTKQVLVGFLLILAAIELALVLTEDSGQATVPAIRYTNPSLYLGTWLLVLLIQHS
RRWCIQKDSWFLSLFWILSVLCGVFQFQTLIRTLLKGSNFNLAYSCLFFICYALQILILI
LSAFSEKDASSNNPSFTASFLSSITFSWYDSIILKGYKQPLTLEDIWDVNEKMKTKTLVS
TFEKRMVRELQKARKELQRRQQRKSQGNTGDRLHGLNKNQSQSQDILVLEEVKKKKKKSG
TTENFPKSWLVKALFKTLYGILLKSFFLKLVHDLLMFLNPQLLKLLISFANTRDMYAWTG
YLYSVLFFVVALVQSLCLQGYFQMCFMLGVTVRTTIMASIYKKALTLSNQARKQYTVGET
VNLMSVDAQKLMDVTSYLHLLWSNVLQITLSIYFLWTELGPSVLAGVGVMILLIPVNGIL
ASKSRAIQVKNMKNKDKRLKIMNEILSGMKILKYFAWETSFKNQVHGLRKKELKNLLTFG
QMQSMMMFLLYLTPVLVSVITFSVYTLVDSNNILDAEKAFTSITLFNILRFPLSMFPMVI
SSILQASVSRDRLEKYLGGDDLDTSAIRHDCHFDKAVQFSEASFTWDQDSEATIRDVNLD
IMPGQLVAVVGTVGSGKSSLMSAMLGEMENVHGHVTIKGTVAYVPQQSWIQNGTIKDNIL
FGSEFDEKRYQQILEACALLQDLEVLPGGDLAEIGEKGINLSGGQKQRISLARATYQNSD
IYVLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSIHFLPQVDEIVVLGHGTIL
EKGSYSSLLAKKGSFAKILKTFTKQTGPEEEATVNEDTEDDDDCGLMPSVEEIPEDVASL
ATKRENSLHRTLSRSSRSNSRHWKSLRNSLKTRNVNTLKEEEETVKGQKLIKKEFIQTGK
VKFSIYLKYLGAIGWYSIFFIILAYVINSVAYIGSNLWLSAWTNDSKTYNGTDYPASQRN
LRIGVYAALGCVQGAFVLIANLWSAHGSTHASNILHRQLLSSILRAPMSFFDTTPTGRIV
NRFAGDISTVDDTLPLSLRSWILCFLGIISTLVMICTATPIFVVVIIPLGIIYVSVQIFY
VATSRQLKRLDSVTRSPIYSHFSETVSGLSVIRAFEHQQRFLQHNERQIDTNQKCVFSWI
VSNRWLAIRLELIGNLIVFFSSLMMVIYKDNLRGDTVGFVLSNALNITQTLNWLVRMTSE
IETNIVAVERINEYIKVENEAPWVTDKRPPPGWPSKGEIQFNNYQVRYRPELDLVLRGIT
CDIRSMEKIGVVGRTGAGKSSLTNGLFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIP
QDPILFSGTLRMNLDPFNNHSDEEIWKALELAHLKSFVSGLQLGLSHEVTEAGDNLSVGQ
RQLLCLARALLRKSKILIMDEATAAVDLETDRLIQTTIQKEFSHCTTITIAHRLHTIMDS
DKIMVLDNGKIVEYSSPQELLRKSGPFYLMAKEAGIESVDSTSL |
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| NT seq |
4635 nt +upstreamnt +downstreamnt
atgctggagaagttctgcaactctacattttggaattcttcattcttggatagcccagaa
gcggacctgccactttgttttgagcaaactgttctggtgtggattcctttgggtttcctt
tggctcctggctccttggcagcttcttcatgtgtatagatctaagatcaagagatctcct
ataaccaaactctacctcactaagcaggtgcttgttggctttcttcttattctagcagcc
atagagctggcccttgtactcacagaagactctggacaagccacagtccctgccattaga
tataccaatccaagcctttacctgggtacatggctcctggttttgctgatccaacacagc
aggcgatggtgcatacagaaggattcttggttcctctccctattctggattctctcagta
ctctgtggcgttttccaatttcagactctgatccggacactcttaaagggcagcaatttt
aacctggcctattcctgcctgttcttcatctgctatgcactacagatcctgatcctgatc
ctttcagcattttccgaaaaagatgcctcctcaaataatccatcattcacagcctcattt
ctgagtagcattacgtttagttggtatgacagcatcattttgaaaggctacaagcaacct
ctgacacttgaagatatctgggatgtcaatgaaaagatgaaaaccaagacactggtcagc
acgtttgaaaaacgcatggtacgagagctgcagaaggccaggaaggaactccagagacgg
cagcagaggaagtcccaggggaacaccggagacaggctgcatggactgaacaagaatcag
agtcaaagccaagatatccttgtcctggaagaagttaaaaagaaaaaaaagaagtctggg
acaacagaaaactttcccaagtcctggttggtcaaggctctcttcaaaactttatacggc
atactcttgaaatcattcttcctgaagctggtgcacgacctcctcatgtttctgaaccct
cagctgctgaagttgctgatctcctttgcaaatacccgagacatgtatgcgtggaccggg
tatctctattcagtcctcttctttgtggtggccctcgtgcagtctctctgccttcagggc
tactttcaaatgtgcttcatgctgggcgtcactgtgcggacaaccatcatggcgtccata
tacaagaaggcgctgaccctatccaaccaggccaggaagcagtacactgttggagaaaca
gtgaacctgatgtctgtggatgcccagaagctcatggatgtgaccagctaccttcatctg
ctgtggtcaaatgttctccagattactttatccatctacttcctatggaccgagctggga
ccctctgtcttagcgggtgttggggtgatgatactcctaatcccagttaatgggatactt
gcctctaagagcagagctattcaggtaaaaaatatgaaaaataaggacaaacggctaaag
atcatgaatgaaattctcagtgggatgaagatcttgaaatattttgcctgggaaacttca
ttcaaaaaccaagttcatggacttcggaagaaagagctcaagaacctgctgacctttggg
cagatgcagtccatgatgatgtttctcttatacttaactccagtcctggtgtctgtgatc
acgttttcagtttacactctggtggacagcaataatattttggatgcagaaaaggccttc
acctccatcaccctcttcaatatcctgcgctttcccctgagcatgtttcccatggtcatc
tcctccattctccaggccagtgtttccagagaccggctagaaaagtacttgggaggggac
gacttggacacgtccgccattcgccatgactgccatttcgacaaagctgtgcagttttca
gaggcctcctttacctgggaccaggactctgaagccacaatccgagatgtgaacctggac
attatgccaggccagctggtggctgtggtgggcactgtgggctctgggaagtcatccttg
atgtcagccatgctgggagaaatggaaaatgtccacgggcacgtcaccatcaagggcacc
gtagcctatgtcccccagcagtcctggatacagaatggcaccataaaggacaacatcctc
tttggatccgagtttgatgaaaagagataccagcagattctggaggcctgtgccctcctg
caagacttggaggtgttgcctggaggagacctggctgagattggagagaagggtataaat
ctcagtgggggtcagaagcagcggatcagcctggccagagctacctatcagaattcagac
atctacgttctggatgaccccctgtcggccgtggatgctcatgtgggaaaacatattttc
aataaggtcttgggtcccaatggcctattgaaaggcaagactcgactcttggttacgcac
agcattcactttcttccccaagtggatgagatcgtggttctggggcatggcaccatcttg
gagaagggatcctacagctctctgctggccaagaaaggatcatttgctaagattctgaag
acattcacaaaacagacgggtcctgaggaagaggccacagtcaatgaggacactgaagat
gatgatgactgtgggctgatgcccagtgtggaggaaatccctgaggatgtggcctcctta
gccacaaaaagagagaacagccttcatcgaacactcagtcgcagttctaggtccaatagc
aggcattggaaatccctaagaaactctctgaaaactcggaatgtgaataccctgaaggag
gaagaagaaacagtgaaaggacaaaaactaattaagaaggaattcatacaaactggaaag
gtgaagttctccatctacctcaagtacctaggagcaataggatggtattcaatattcttc
atcatcttggcctatgtgatcaattctgtggcttatattggatccaacctctggctcagt
gcttggaccaatgactctaaaacctataatggcactgactatccagcgtctcagagaaac
ctgagaattggcgtctatgcagctctgggatgcgtgcaaggtgcatttgtgctcatagca
aatctctggagtgcccatggttctactcacgcatcaaacatccttcataggcaactgcta
agcagtatccttcgagcacccatgagtttctttgacacaacgcccacaggccggattgtg
aacaggtttgctggggatatttccacagtggatgacacccttcccttatccttgcgcagc
tggatattgtgcttcctgggaataatcagcacccttgtcatgatctgcacggccactcca
atcttcgtcgtggtcatcattcctcttggcatcatttatgtgtctgttcagatattttat
gtggccacttcccgccagctgaaacgcctggactctgtcaccaggtccccaatctactct
cacttcagtgagacagtgtcaggtttgtccgtcatccgtgcctttgagcaccagcagcga
tttctgcaacacaatgagaggcagattgacaccaaccagaaatgtgtcttctcctggatt
gtctccaacaggtggcttgcaattcgtctggagctgattgggaacctgattgtcttcttt
tcatccctgatgatggttatttataaagataacctccgtggagacactgtgggctttgtt
ttgtccaatgcgcttaatatcacacagaccttgaactggctagtgaggatgacgtcagaa
atagagaccaacattgtggctgttgaaagaataaatgagtacataaaagtggaaaacgag
gcaccctgggtgactgataagagacctcccccaggatggcccagcaaaggggagatccag
tttaacaactaccaagtgcggtaccggccggagctggatcttgtactgagagggatcact
tgtgacattaggagcatggagaagattggtgtggtcggcaggacaggagctgggaagtct
tccttgacaaatggcctcttcagaatccttgaggctgcaggtggccagatcatcattgat
ggagtagatattgcttccattgggctccatgacctccgagagaagctgaccatcatcccc
caggatcccatcctgttctctggaaccctgaggatgaacctagacccttttaacaaccac
tcagatgaggagatttggaaggccctggagctggctcacctcaaatcctttgtatctggc
ctgcaacttgggttgtctcatgaagtgacagaagctggtgacaaccttagcgtaggacaa
aggcaactgctgtgcctggcccgggctctgcttcggaaatccaagattctgatcatggac
gaggccaccgctgccgtggatctggagactgatcgcctcatccagacaaccatccaaaag
gagttctcccactgcaccaccatcaccatcgctcacaggctgcacaccatcatggacagc
gacaagataatggtcttagacaacgggaagattgtagagtatagcagccctcaagaactg
ctgagaaaatcgggtcccttttatttgatggccaaagaggctggcattgaaagtgtggat
agtacatcactctga |
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