Mustela lutreola (European mink): 131828905
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Entry
131828905 CDS
T09578
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk00760
Nicotinate and nicotinamide metabolism
mlk01100
Metabolic pathways
mlk04068
FoxO signaling pathway
mlk04148
Efferocytosis
mlk04152
AMPK signaling pathway
mlk04211
Longevity regulating pathway
mlk04213
Longevity regulating pathway - multiple species
mlk04218
Cellular senescence
mlk04310
Wnt signaling pathway
mlk04922
Glucagon signaling pathway
mlk04936
Alcoholic liver disease
mlk05031
Amphetamine addiction
mlk05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
131828905 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
131828905 (SIRT1)
04068 FoxO signaling pathway
131828905 (SIRT1)
04152 AMPK signaling pathway
131828905 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
131828905 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
131828905 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
131828905 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
131828905 (SIRT1)
04213 Longevity regulating pathway - multiple species
131828905 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
131828905 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
131828905 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
131828905 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mlk03036
]
131828905 (SIRT1)
03029 Mitochondrial biogenesis [BR:
mlk03029
]
131828905 (SIRT1)
Enzymes [BR:
mlk01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
131828905 (SIRT1)
Chromosome and associated proteins [BR:
mlk03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
131828905 (SIRT1)
Mitochondrial biogenesis [BR:
mlk03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
131828905 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
131828905
NCBI-ProteinID:
XP_059026102
LinkDB
All DBs
Position
4:complement(57904329..57930579)
Genome browser
AA seq
747 aa
AA seq
DB search
MADEAALALQPGGSPSAVAAEREAASPPVGEPLRKRPRKDCPGLGRSPGEPGGAAPEREV
PAATGGCPAAAAALWREAAASAAAAGGEREAQAATAGEGDNGPGLQGLSREPPPADDFYD
DDDDDEGEEEEEAAAAAIGYRDDLLFDDEIITNGFHSCESDEDDRASHASSSDWTPRPRI
GPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINT
IEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAIDFPDLPDPQAMFDIEYF
RKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQC
HGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQF
HRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDC
DVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEDSSSPE
RTSPPHSSVIVKLLDQASKSNVDDPGVSESNDCMEEKSQEGQNSTKNIESVIEQVESPDV
RNVGSNTGEKNERTLVADSVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSD
SEDDILSSSSCGSNSDSGTCQSPSLEEHLEDESEIEEFYNGLEDEADVNDRAGGTGFGIG
GGDQEAVSEALSMKQEATDINYPSNKS
NT seq
2244 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcccttcagcccggcggctccccctcggcggtggcggcc
gagagggaggccgcgtcgccgcccgtcggggagccacttcgcaagagaccacggaaagac
tgtcccggcctggggcggagcccgggcgagcccggtggggcggcccctgaacgtgaggtg
ccggcggcgaccgggggctgccccgcggcggcggcggctctgtggcgggaggcggcggcg
tcggcggcggcggcgggcggggagcgggaggcccaggcggcgacggccggagaaggagac
aatgggccgggcctacagggcctatcccgggagccgccgccggccgacgacttctacgac
gacgacgacgacgacgagggcgaagaggaggaagaggcggcggcggcagcgattgggtac
cgagatgaccttctttttgatgatgaaataatcaccaatggttttcattcctgtgaaagt
gatgaggatgatagagcctcacatgcaagctctagtgactggactccaaggccacggata
ggtccatatactttcgttcagcaacatctcatgattggcacagatcctcgtacaattctt
aaagatttgctaccagaaacaattcctccacctgaactggatgatatgacactgtggcag
attgttattaatatcctttcagaaccaccaaaaagaaaaaaaagaaaagatattaataca
attgaagatgctgtgaaattactgcaagagtgcaaaaaaataatagttctgacaggagct
ggggtttctgtttcttgtggaatacctgacttcaggtcaagagatggtatttatgctcgc
cttgcaatagacttcccagaccttccagatcctcaagcaatgtttgatattgaatatttc
agaaaagatccaagaccattcttcaagtttgcaaaggaaatatatcctggacagttccaa
ccatctctctgtcacaaattcatagccttgtcagataaagaaggaaaactacttcggaac
tatacgcagaacatagatacactggaacaggttgcgggaatccagaggataattcagtgt
catggatcctttgcaacagcatcttgtctgatttgtaaatacaaagtagactgtgaagct
gtacgaggagatatttttaatcaggtggttcctcgttgtcctagatgcccagcagatgag
ccacttgctatcatgaaaccagagattgtcttttttggtgaaaatttaccagagcagttt
catagagccatgaaatacgacaaagatgaagttgatctcctcattgttattgggtcttcc
ctgaaagtaagaccagtagcactaattccaagttccataccccatgaagtgcctcagata
ttaataaatagagaacctttgcctcatctgcattttgatgtagagcttcttggagactgt
gatgtcataataaatgaattatgtcataggttaggtggtgaatatgccaaactttgctgc
aaccctgtaaagctttcagaaattactgaaaaacctccacgaacacagaaagaattggct
catttgtcagagttgccacccacacctcttaatatttcagaagactcaagttcaccagaa
agaacttcaccaccacattcttcagtgattgttaaacttttagaccaagcatctaagagt
aatgttgatgatcctggtgtgtccgagtcaaatgattgtatggaagaaaaatcacaggaa
ggacagaattctactaagaacattgaaagcgttattgaacaggtggaaagtccagatgtg
aggaatgttggctctaatactggggagaaaaatgaaagaactttagttgctgactcggtg
aggaagtgctggccagctagacttgcaaaggagcagattagcaaacggcttgatggtaac
caatatctgttcttaccaccaaaccgttatatttttcatggcgctgaggtatattcagac
tctgaagatgacatcttatcctctagttcttgtggcagtaacagtgatagtggaacatgc
cagagtccaagtttagaagaacacttggaggatgaaagtgagattgaagaattttacaat
ggtttggaagatgaagctgatgttaatgacagagctggaggaactggatttggaattggt
ggcggtgatcaagaggcagtcagtgaagctctatccatgaaacaggaagcaacagacatt
aactatccatcaaacaaatcataa
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