Mustela lutreola (European mink): 131829935
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Entry
131829935 CDS
T09578
Symbol
NOS3
Name
(RefSeq) LOW QUALITY PROTEIN: nitric oxide synthase 3
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk00220
Arginine biosynthesis
mlk00330
Arginine and proline metabolism
mlk01100
Metabolic pathways
mlk04020
Calcium signaling pathway
mlk04022
cGMP-PKG signaling pathway
mlk04066
HIF-1 signaling pathway
mlk04071
Sphingolipid signaling pathway
mlk04151
PI3K-Akt signaling pathway
mlk04370
VEGF signaling pathway
mlk04371
Apelin signaling pathway
mlk04611
Platelet activation
mlk04915
Estrogen signaling pathway
mlk04921
Oxytocin signaling pathway
mlk04926
Relaxin signaling pathway
mlk04931
Insulin resistance
mlk04933
AGE-RAGE signaling pathway in diabetic complications
mlk05415
Diabetic cardiomyopathy
mlk05417
Lipid and atherosclerosis
mlk05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
131829935 (NOS3)
00330 Arginine and proline metabolism
131829935 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
131829935 (NOS3)
04371 Apelin signaling pathway
131829935 (NOS3)
04066 HIF-1 signaling pathway
131829935 (NOS3)
04020 Calcium signaling pathway
131829935 (NOS3)
04071 Sphingolipid signaling pathway
131829935 (NOS3)
04022 cGMP-PKG signaling pathway
131829935 (NOS3)
04151 PI3K-Akt signaling pathway
131829935 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
131829935 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
131829935 (NOS3)
04921 Oxytocin signaling pathway
131829935 (NOS3)
04926 Relaxin signaling pathway
131829935 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
131829935 (NOS3)
05418 Fluid shear stress and atherosclerosis
131829935 (NOS3)
05415 Diabetic cardiomyopathy
131829935 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
131829935 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
131829935 (NOS3)
Enzymes [BR:
mlk01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
131829935 (NOS3)
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Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
131829935
NCBI-ProteinID:
XP_059028224
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Position
4:196791580..196809267
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AA seq
1203 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPTSSEPSRAPAPTPAPPPAPDRSPPLT
RPPDGPKFPRVKNWEVGSITYDTLSAQSQQDGPCTPRRCLGSLVFPRKLQSRPSRDPQPT
EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPP
ELFALPPELVLEVPLEHPTLEWFGALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGARNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPDPW
KGSGSKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAA
RDIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRATIL
VRLDTGGQEALQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPGGP
PPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEESSEQQELESLSQDPRRY
EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPTLPCILVGPGTGIXP
FRGFWQERLHDIDSKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSRE
PDSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDMELD
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGPDT
PSP
NT seq
3612 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcccgggcccccctgtggcctggggctgggc
ctgggcctggggctgtgcggcaagcagggtccggcctcccccacctcctctgagcccagc
agggcacccgcgcccacgcccgcgcccccacccgcaccagaccgcagccccccactcacc
cggcccccggacgggcccaagttccctcgagtgaagaactgggaggtggggagcatcacc
tacgataccctgagtgcccagtcacagcaggatgggccctgcaccccccgacgctgcctg
ggctcgctggtgttcccgcggaaactgcagagtcggccatctcgggacccccaacccacg
gagcagctgctgagtcaggccagggactttatcaaccagtactacagctccatcaagagg
agcggctcccaggcccatgagcagaggcttcaggaggtggaagccgaggtggcagccacg
ggcacctaccagctccgggagagtgagctggtgttcggggccaagcaggcctggcgcaac
gcaccccgctgcgtgggccggatccagtgggggaagctgcaggtgtttgatgcccgggac
tgcagctcagcccaggagatgttcacctacatctgcaaccacatcaagtatgccaccaac
cggggcaacctccgctcagccatcacagtgttcccccagcgcgccccaggccggggagac
ttccgaatctggaacagccagctggtacgctatgcgggctacaggcagcaggatggctca
gtgcggggggacccagccaacgtggagatcaccgagctctgcatccagcatggctggacc
ccaggaaacggccgctttgacgtgctgccactcctgctccaggccccggatgagccccca
gagctctttgctctgccccccgagctggtcctcgaggtgcccctggagcaccccacgctg
gagtggtttggggccctgggcctgcgctggtacgccctcccggcggtgagtaacatgctg
ctggagatcgggggcctggagttccccgcagcccctttcagcggctggtacatgagcacg
gagatcggcgcgcggaacctgtgtgaccctcaccgatataacatcctggaggatgtggca
gtctgcatggacttggacaccaggacaacctcatccctgtggaaagacaaggcagcggtg
gaaatcaacttggccgtgctgcacagttaccagctggccaaagtgaccattgtggaccac
cacgctgccaccgcctccttcatgaagcacctggagaacgagcagaaggctagggggggc
tgccctgccgattgggcctggattgtgccccccatctctggcagcctcacccctgtcttc
catcaggagatggtcaactacgtcctgtcccctgccttccgctatcagccagacccatgg
aaggggagtggatccaagggtaccggcatcaccaggaagaagacctttaaggaagtggcc
aatgcagtgaagatctcagcctcgctcatgggcaccgtgatggcaaagcgagtgaaggcg
accatcctgtatggctccgagaccggccgggcccagagctatgcacagcagctggggaga
ctcttccggaaggctttcgacccccgggtcttgtgcatggatgagtatgatgtggtgtcc
cttgagcatgagacgctggtgttggtggtgaccagtacgtttgggaatggtgacccccca
gagaatggagagagttttgcggcggccctgatggagatgtcgggcccctacaacagctcc
cctcggccagaacagcacaagagttacaaaatccgcttcaacagcgtctcttgctcagac
ccgctggtgtcctcttggaggcggaagagaaaggagtccagtaacacagacagcgcaggg
gccctggggaccctcaggttctgtgtgttcgggctgggctcccgggcatacccccacttc
tgcgcctttgctcgtgcggtggacacacggctggaagagctgggcggggagcggctactg
cagctgggccagggagatgagctgtgcggccaggaggaggccttccgtggctgggcccag
gctgccttccaggcctcctgtgagactttctgcgtgggagaggatgccaaggccgctgcc
cgggacatattcagccccaaacggagctggaagcgccagcggtaccggctgagcacccag
gccgagggcctccagctgctgccaggcctgatccacgtgcacaggagaaagatgttccag
gctacggtcctctcagtggaaaacctgcaaagcagcaagtccacccgggccaccatcctg
gtgcgcctagacaccggaggccaggaggcgctacagtaccagcccggggatcacataggc
atctgcccgcccaaccggccaggcctcgtggaggcactgctgagccgcgttgaggatcct
cctccacccggcgagcctgtggctgtggagcagctggagaagggcagccctggtggcccg
ccccctggctgggttcgggacccccggctgcccccatgcacactgcgccaggctctcacc
ttcttcctggacatcacttccccgcccagtcctcaactccttcgactgctcagcaccctg
gccgaagagtccagcgaacagcaggagcttgagagcctcagccaggacccgcggcggtac
gaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagtttccatcg
gtggccctgcccgcgccgctgctcctcacccagctgcccctgctccagccccggtactac
tcagtcagctcggcgcccagcgcccacccaggagagatccacctcacagtagctgtgcta
gcatacaggacacaggacggactgggcccccttcattatggagtctgctccacgtggctg
agccagctgaaggccggggatcctgtaccctgcttcatcaggggggctccctccttccgg
ctgccacctgaccccaccttgccctgcatcctagtgggccctggcacaggtattngcccc
ttccggggattctggcaggagcggctgcatgacattgacagcaaaggcctgcagcccgcc
cccatgactttggtgttcggctgccgatgctcccagctcgaccacctttaccgcgacgag
gtgcaggatgcccagcagcgcggagtttttgggcgcgtcctcaccgccttctcccgggag
cccgacagccctaagacctacgtgcaggacatcctgcggacggagctggctgctgaggtg
caccgcgtgctgtgcctcgagcggggccacatgtttgtgtgcggcgacgtcaccatggca
accagcgttctgcagacggtgcagcgcatcctagcgacggagggcgacatggagctggac
gaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggacattttc
gggctcacactgcgtacccaggaggtgacaagccgcatacgcacccagagcttttccttg
caggagcgacatctgcggggcgcagtgccctgggcgttcgacccgcccgggccagacacc
cccagcccctga
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integrated database retrieval system