Mustela lutreola (European mink): 131833379
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Entry
131833379 CDS
T09578
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk00230
Purine metabolism
mlk01100
Metabolic pathways
mlk04024
cAMP signaling pathway
mlk05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
131833379 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
131833379 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
131833379 (PDE10A)
Enzymes [BR:
mlk01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
131833379 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
131833379 (PDE10A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
131833379
NCBI-ProteinID:
XP_059032554
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All DBs
Position
6:2937346..3506516
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AA seq
1029 aa
AA seq
DB search
MASPVEPLAPRPHAPLPAAGDEPGSGPGKLRPEPWRGVAGGGSAVGPGALCARGSGGWGS
ARAPLALALSSPVPSSSPSSFYFWPPPPPAPPSLLPSSSAFHLPVRLPGRGGAAAAAAAR
GGGGGGDAGGGGGGGGPEAAPLSVPPSSSPRGGGGDGRRRLFLCSALQALLLPARAGLRL
PLGPAARRAGSPGFPGAGGGCPGPSPGGGGGRTPRRPGDAGFALAAASPLLFGSDMEDGP
SNNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKPE
DESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALY
FLGECNNSLCVFTPPGIKEGQPRLIPAGPIAQGTTTSAYVAKSRKTLLVEDILGDERFPR
GTGLESGTRIQSVLCLPIVTAIGDLIGVLELYRHWGKEAFCMSHQEVATANLAWASVAIH
QVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHK
NKELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNRE
VDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCA
NMYHRIRHSECIYRVTMEKLSYHSICTAEEWQDLMRFSLPVRLCKEIELFHFDIGPFENM
WPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNH
GLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQL
EGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRV
IGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQG
QLGFYNAVAIPCYTTLTQIFPPTEPLLKACRNNLSQWEKVIRGEESAVWTSSRPAAPGPS
EKLPVKVDD
NT seq
3090 nt
NT seq
+upstream
nt +downstream
nt
atggccagccccgtagagccgctcgctccccgcccccacgcccccctgcccgcggccggg
gacgagcccggatccggccccggcaaactccgcccggagccctggcgcggcgtggccggc
ggggggagcgcggtgggcccgggcgccctgtgtgcgcgcggcagcggcggctggggctcg
gcccgcgctcccctcgcgctcgccctctcctcccctgtcccctcctcctctccgtcttcc
ttttacttctggccgccgccccccccggcccccccttctcttctcccctcctcgtctgcc
ttccacctccccgtgcgtctcccaggaagggggggcgcagcggcggcggcggcggcgcga
ggaggcggcggcggcggcgatgctggcggcggcggcggcggcggaggaccagaggcagct
cccctgagcgtccctcccagcagtagtccccgcggcggcggcggcgacgggcggcggcgg
ctcttcctctgctccgcgctccaggctttgctgctcccagcccgcgccgggctccggctc
ccgctcggcccggccgcccgccgcgcgggctcccccggcttcccgggtgccggcgggggc
tgccccggccccagccccggcggcggcggcggccgaactccgcggcggcccggagacgcc
ggcttcgccctcgccgccgcgtcccccctgctattcggctccgacatggaagatggacct
tctaacaacgcgagctgcttccgaaggttgacggagtgtttcctgagccccagtttgaca
gatgaaaaagtgaaggcgtatctttctctccatccccaggtgttggacgagtttgtatcg
gaaagtgttagtgcagagactgtagaaaaatggctgaagaggaaaaacaacaaaccagaa
gatgagtcggctcctaaggaagtcagcaggtaccaagacacgaatatgcagggagttgtg
tatgaactcaacagctacatagaacagcggttggatacaggaggagacaaccagctactc
ctctatgaattgagtagcatcattaaaatagccacaaaagctgatggatttgcactgtat
ttccttggagagtgcaataatagtctgtgcgtcttcactccgcctggaatcaaagaagga
cagccccggctcatccctgctgggcccattgcccagggaaccaccacctctgcctacgtg
gccaagtccagaaaaacattgctagtggaggacatccttggggatgagcgatttccgaga
ggtactggactggagtcggggactcgtatccagtcggtgctctgtttaccgattgtcact
gccattggcgatttgatcggcgtcctcgagctgtatcggcactggggcaaagaagccttc
tgtatgagccaccaggaggtcgcgacagccaatctcgcctgggcttccgtagcaatacat
caggtgcaggtatgcagaggccttgctaaacagaccgaactgaatgacttcctacttgat
gtgtccaagacatattttgataacatagtcgcaatagactctctacttgaacacataatg
atatatgcaaaaaatctggtgaatgcagaccgctgtgcacttttccaggtagaccataag
aacaaggagttatattcagacctttttgatattggagaggaaaaggaaggaaaacccatc
ttcaagaagaccaaagagataagattttcaattgagaaagggattgccggtcaggtagca
agaacaggggaagtcctgaacattccagatgcctatgcagacccacgcttcaacagggaa
gtggacttgtacacggggtacacgacccggaatatcctgtgcatgcccatcgtgagccga
ggcagcgtgatcggcgtggtgcagatggtgaacaagatcagcggcagtgccttctcgaaa
acggacgagaacaacttcaagatgttcgccgtcttctgtgctttagccttacactgtgcc
aatatgtaccaccgaatccgccattccgagtgcatttaccgggtgacgatggagaagctg
tcctaccacagcatctgcacggccgaggagtggcaggacctcatgcgcttcagcctcccc
gtgcgcctctgcaaggagatcgaactattccactttgacattggtccttttgaaaacatg
tggcctggaatttttgtgtacatggtccatcggtcctgtgggacatcctgctttgagctt
gaaaagttgtgtcgctttattatgtctgtgaagaagaactaccggcgggtgccgtaccac
aactggaagcacgccgtcaccgtggcacactgcatgtacgccatcctgcagaacaaccac
gggctcttcaccgacctggagcgcaaaggactgctgatcgcgtgcctgtgtcatgacctg
gaccacagaggcttcagcaacagctacctgcagaagttcgaccacccgctggcggctctc
tactccacgtccaccatggagcagcaccacttctcccagaccgtgtccatcctccagctg
gaagggcacaatatcttctccaccctgagctccagtgaatatgaacaggtgcttgagatc
atccgcaaagccatcattgccacagaccttgctctgtactttggaaacaggaaacagttg
gaagagatgtaccagaccggatcgctaaaccttaataatcaatcacatagagatcgtgtc
attggtctgatgatgactgcctgtgatctttgctctgtaacaaaactatggccggttaca
aaattgacagcaaatgatatatatgcagagttctgggctgagggtgatgagatgaagaag
ctgggaatacagcctattcccatgatggacagagacaagaaggatgaggtcccacaaggc
cagctgggcttctacaacgccgtggccatcccctgctacaccacgctcacgcagatcttc
ccgcccaccgagccgctcctcaaagcctgcaggaacaacctcagccagtgggagaaggtg
atccgaggggaggagagcgccgtgtggacctcatcccggcccgcggcccccgggccctcg
gagaagctgcccgtgaaggtcgacgactga
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