KEGG   Mustela lutreola (European mink): 131839461
Entry
131839461         CDS       T09578                                 
Symbol
GRM5
Name
(RefSeq) metabotropic glutamate receptor 5 isoform X1
  KO
K04604  metabotropic glutamate receptor 5
Organism
mlk  Mustela lutreola (European mink)
Pathway
mlk04020  Calcium signaling pathway
mlk04072  Phospholipase D signaling pathway
mlk04080  Neuroactive ligand-receptor interaction
mlk04082  Neuroactive ligand signaling
mlk04540  Gap junction
mlk04720  Long-term potentiation
mlk04723  Retrograde endocannabinoid signaling
mlk04724  Glutamatergic synapse
mlk05010  Alzheimer disease
mlk05016  Huntington disease
mlk05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:mlk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    131839461 (GRM5)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    131839461 (GRM5)
   04082 Neuroactive ligand signaling
    131839461 (GRM5)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    131839461 (GRM5)
   04720 Long-term potentiation
    131839461 (GRM5)
   04723 Retrograde endocannabinoid signaling
    131839461 (GRM5)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    131839461 (GRM5)
   05016 Huntington disease
    131839461 (GRM5)
   05022 Pathways of neurodegeneration - multiple diseases
    131839461 (GRM5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:mlk04030]
    131839461 (GRM5)
G protein-coupled receptors [BR:mlk04030]
 Metabotropic glutamate receptor family
  Glutamate (metabotropic)
   131839461 (GRM5)
SSDB
Motif
Pfam: ANF_receptor 7tm_3 GluR_Homer-bdg NCD3G Peripla_BP_6 DUF5438
Other DBs
NCBI-GeneID: 131839461
NCBI-ProteinID: XP_059042918
LinkDB
Position
1:217316970..217853367
AA seq 1217 aa
MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAV
REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS
EEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS
DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGI
CIAHSYKIYSNAGEQSFDKLLKKLRSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFL
LLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNLRNPWFQEFWQ
HRFQCRLEGFAQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP
GYAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRYEIMNFKEMGKDYFD
YINVGSWDNGELKMDDDEVWSKKNNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKEN
EYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTAV
FIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS
ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIM
HDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYT
TCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS
TVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSVG
NGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSIHINKKENPNQTAVIKPFPKSTESRG
LGAGGAGGGAGAAGGAGGVAGGAGGGPGGAEPPDAGPKALYDVAEAEEHFPAPARPRSPS
PISTLSQRAGSASRTDDDVPSLHSEPAARSSSSQGSLMEQISSVVTRFTANISELNSMML
STAAPAPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAPPAAVAAAAAPPV
GGAAEEPPAGAGPEAAAGKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSP
KYDTLIIRDYTQSSSSL
NT seq 3654 nt   +upstreamnt  +downstreamnt
atggtccttctgttgatcctgtcagttctgcttttgaaagaagatgtccgtgggagtgca
cagtccagcgagaggagggtggtggctcacatgccgggtgacatcattattggagctctc
ttttctgtccaccaccagcccacagtggacaaagttcatgagaggaagtgtggggcagtt
cgtgaacagtatggcattcagagagtggaggccatgctgcatactctggaaaggatcaac
tcagaccccacgctcttgcccaacatcaccctgggctgtgagataagggattcctgctgg
cattcggctgtggccctagagcagagcattgagttcataagggactccctcatttcttca
gaagaagaagaaggtttggtgcgctgcgtggatgggtcttcctcttccttccgctccaag
aagcccatcgtaggggtcattgggcctggctccagttctgtggccattcaggtccagaac
ttgctccagcttttcaacatacctcagattgcttactcagcaacaagcatggatctgagt
gacaagactctgttcaagtacttcatgagggttgtgccctcagatgctcagcaagcacgg
gccatggtggacatagtgaagaggtacaactggacctatgtgtcagctgtgcacacagaa
ggcaactatggagagagtgggatggaagctttcaaagatatgtcagccaaggaaggaatt
tgcatcgctcactcttacaaaatctatagcaatgcaggggaacagagctttgataaactg
ctgaagaagctcaggagtcacttgcccaaggcccgggtggtggcctgcttctgtgaaggc
atgacggtgagaggtctgctgatggccatgaggcgcctgggtctagcaggcgaatttctg
cttctgggcagtgatggctgggctgacaggtatgatgtgacagatggatatcagcgagaa
gctgttggtggaatcacaatcaagctccaatctcctgatgtcaagtggtttgatgattat
tatctgaagctccgtccagaaacaaaccttcgaaacccttggtttcaagaattttggcag
catcgttttcagtgccggctggaaggttttgcacaggagaacagcaaatacaacaagact
tgcaatagttctctgactctgagaacacatcacgttcaggattccaaaatgggatttgtg
atcaatgctatctattccatggcctatggactccacaacatgcagatgtccctctgccca
ggctatgcgggcctctgtgatgcaatgaagccaatcgatggacggaaacttttggattcc
ctgatgaaaaccaattttactggggtttctggagatatgatcctctttgatgagaatgga
gactctccaggaaggtatgaaataatgaatttcaaggaaatgggaaaagattattttgat
tacatcaatgttggaagctgggacaatggagaattaaaaatggatgatgatgaagtatgg
tccaagaaaaacaacatcatcagatccgtgtgcagtgaaccatgtgagaaaggccagata
aaggtgatccggaagggggaagtcagctgttgttggacctgtacaccctgtaaagaaaat
gagtatgtctttgatgagtacacctgcaaggcgtgccagctggggtcgtggcccactgat
gaccttacaggctgtgacttgatcccagtacagtatctccgctggggtgatcctgagccc
attgcagctgtggtgtttgcctgccttggcctgctggccaccctatttgtcactgcagtc
ttcatcatttaccgtgatacgccagtagtcaagtcctccagcagggaactctgctatatc
atccttgccggcatctgcctgggttacttatgtaccttctgcctcattgcaaagcccaaa
cagatttattgctaccttcagagaattggtatcggtctttccccagccatgagctactca
gcccttgtaaccaagaccaatcgtattgcaaggatcctggccggcagcaagaagaagatc
tgtaccaaaaagcccagattcatgagtgcctgtgcccagctggtgattgctttcattctc
atatgcattcagttgggcatcattgttgccctctttataatggagcctcctgatataatg
cacgactacccaagcattagagaagtgtacctgatctgtaataccaccaacctaggggtt
gtcactcctcttggatacaatggcttgctgattttgagctgtaccttctatgctttcaag
acgagaaacgttccagctaacttcaacgaggccaagtatattgccttcactatgtacacc
acctgcattatatggctggcctttgtgccaatctactttggcagcaactacaaaatcatc
accatgtgtttctccgtcagtctcagtgccacagtggcgctgggctgcatgtttgtgccg
aaggtgtacatcatcctggccaaaccagagaggaatgtgcgcagcgccttcaccacctct
accgtggtgcgcatgcatgtgggggacggcaagtcatcctcggcagccagcagatccagc
agcctggtcaacctgtggaagaggaggggctcctctggggaaaccttaaggtacaaagac
aggagactggcccagcacaagtcggaaatagagtgtttcacccccaaagggagtgtgggg
aatggtgggagagcaacaatgagcagctccaacggaaaatccgtcacgtgggcccagaac
gagaagagcagccgggggcagcacctgtggcagcggctgtccatccacatcaacaagaag
gagaaccccaaccaaacggccgtcatcaagcccttccccaagagcaccgagagccgcggc
ctgggcgcgggcggcgcgggcggcggcgcgggggccgcgggcggcgcgggcggggtcgcg
gggggtgcgggcggcggccccgggggggcggagccccccgacgccggccccaaggcgctg
tacgacgtggcggaggccgaggagcacttccccgcgcccgcgcgcccgcgctcgccgtcg
cccatcagcacgctgagccagcgcgcgggctcggccagccgcacagacgacgacgtgccg
tcgctgcactcggagcccgcggcgcgcagcagctcctcgcagggctcgctcatggagcag
atcagcagcgtggtgacccgcttcacagccaacatcagcgagctcaactccatgatgctg
tccaccgcggcgcccgcccccggcgtgggcgccccgctctgctcgtcctacctgatcccc
aaagagatccagctgcccacgaccatgacgacgttcgccgaaatccagccgctgccagcc
atcgaggtcacgggaggcgcgccccccgcggcggtggcggcggcggcggccccgccggta
gggggcgctgccgaagagcccccggcgggggccgggcccgaggctgcggcggggaagccg
gacctggaagagttggtggctctcaccccgccgtccccctttagagactcggtggactcg
gggagtaccacccccaactcgccggtgtcggagtcggccctctgtatcccatcgtctccc
aaatatgacacactgatcataagagattacactcagagctcctcgtcgttgtga

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