Mycolicibacterium litorale: B1R94_11225
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Entry
B1R94_11225 CDS
T05032
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mll
Mycolicibacterium litorale
Pathway
mll00300
Lysine biosynthesis
mll00550
Peptidoglycan biosynthesis
mll01100
Metabolic pathways
mll01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mll00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
B1R94_11225
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
B1R94_11225
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
B1R94_11225
Enzymes [BR:
mll01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
B1R94_11225
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AQT79715
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Position
2398776..2400275
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AA seq
499 aa
AA seq
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MIALSVARIAEIVGGELADISPDEAAARVVTGTVEFDSRAVTPGGLFLALPGARSDGHDF
AAAAVEAGAAVVLAARPVGVPAIVVPPAPAADAEAGVLEHDADGSGAAVLAALARLAAAV
AAELVAGGLTIIGVTGSSGKTSTKDLIAAVLRPLGEVVAPPGSFNNELGHPWTVLRATTD
TDYLVLEMSARHPGNIAALAAIAPPSIAVVLNVGTAHLGEFGSREVIAETKSELVQAVRS
SGVAILNVDDPMVAAMAGKTAARVVRVGQSAQADVRAVDVELDDLARPRFTLIAGGQQVA
VRLAVHGEHQVGNALSATAVAIECGAGLAQVAAALATAGPESRRRMDVRTRADGVIVVND
AYNANPDSMRAGLQALAVLARASDRRSGKRRSWAVLGEMAELGEESITEHDRVGRLVVRL
DISRLVVVGTGRPMSAMHHGAVMEGSWGSESTVVDDADAALELLRAELQPGDVVLVKASN
SVGLGAVAEALLAEDGVES
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccttgagcgtcgcccggatcgccgagatcgtgggcggtgaactggccgatatc
agccctgacgaggccgccgcgcgggtggtgaccggaaccgtcgagttcgactcgcgggcg
gtcactccgggcggattgttcctggcgctgcccggggcgcggtccgacggccacgatttc
gccgcggccgccgtcgaggccggcgcagcggtggtcctcgccgcccgcccggtcggggta
cccgcgatcgtggtgccgccggcgccggccgccgacgcggaagccggtgtgctggagcac
gacgcggacggctccggggcggcggtgctggccgccctggcgcggctggccgcggcggtg
gccgccgaactggtggccggtgggctgaccatcatcggggtgacggggtcttcgggcaag
acgtccaccaaggacctgatcgccgcggtgctgcggccgctgggcgaggtggtggccccg
ccgggttccttcaacaacgaactcggccacccgtggacggtgttgcgtgccaccaccgac
accgactatctggtgctcgagatgtcggcccggcacccgggcaacatcgccgcactcgcc
gccatcgccccgccgtcgatcgccgttgtgctcaacgtcggcaccgcgcacctgggcgag
ttcggctcacgcgaagtcatcgccgagacgaaatcggaactggtgcaggctgttcggtca
tccggggtggccatcctcaacgtcgacgatccgatggtcgccgcgatggcgggcaagacg
gccgcgcgcgtagtgcgggtcgggcaatcggcgcaggccgacgtgcgggccgtcgatgtc
gagctcgacgacctggcccggccccgattcacgctcatcgccggcgggcagcaggtcgcg
gtgcgcctggcggtgcacggcgaacaccaggtcggcaacgcgctgtcggcgaccgcggtg
gccatcgagtgcggggccggtctggcacaggttgccgccgccctggccaccgctggcccc
gaatcgcggcgccggatggatgtgcgcacccgcgccgacggggtgatcgtcgtcaacgac
gcctacaacgccaaccccgattcgatgagagccggcctgcaggcgttggcggtgctggct
cgcgcgagcgatcggcggtccggcaagcgccgcagctgggcggtgctcggggagatggcc
gagctgggcgaggagtcgattaccgagcatgatcgcgtcggccggcttgtcgtgcgctta
gatatcagtcgacttgtcgtcgtcggaactgggaggcccatgagcgccatgcaccacggg
gcggtcatggagggttcctgggggtcggaatccaccgtggtcgacgatgccgacgccgct
ctcgaattgctccgcgctgaactgcagccgggtgatgtcgtgctggtcaaagcgtcgaat
tcggtcgggctgggggcggtggccgaggcgctgctggccgaggacggcgtcgagtcatga
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