Mycobacterium lepromatosis: MLPF_0237
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Entry
MLPF_0237 CDS
T08064
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
mlm
Mycobacterium lepromatosis
Pathway
mlm00230
Purine metabolism
mlm00670
One carbon pool by folate
mlm01100
Metabolic pathways
mlm01110
Biosynthesis of secondary metabolites
Module
mlm_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mlm00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MLPF_0237 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MLPF_0237 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mlm04147
]
MLPF_0237 (purH)
Enzymes [BR:
mlm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
MLPF_0237 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
MLPF_0237 (purH)
Exosome [BR:
mlm04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
MLPF_0237 (purH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
UKN41566
LinkDB
All DBs
Position
254487..256070
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AA seq
527 aa
AA seq
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MSSDDERDMARRPIRRALISVYDKTGLIELAQGLSAAGVDIVSTGSTGKAIAGKGIAVTP
VEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHASELEQLGIEAFELVVVNLYPFSQT
VESGATVDECVEQIDTGGPSIVRAAAKNYPSVAVVTDPLGYVGVLAAVRGGGFTLAERKR
LASMAFQHIVEYDIAVASWMQSTLAPEQPPTAFPQWFSRSWRRSAMLRYGENPHQQAALY
SDPSACPGLAQAKQLHGKNMSYNNFTDADTAWRAAFDHEQSCVAIIKHANPCGIAISSIS
VADAHRKAHECDPLSAYGGVIAVNTEVSLEMAEYVSTIFTEVIVAPSYAPGAVDVLTCKK
NVRVLVASAPLRGGSELRPVSGGLLIQQPDQLDTAGDNPANWTLVTGSPAGPATLTDLVF
AWRACRAVKSNAIVIAANGATIGVGMGQVNRVDAARLAVQRGGDRVRGAVVASDAFFPFA
DGLQALAAAGVTAIVHPGGSVRDAEVTAAAAKAGVTLYLTGVRHFVH
NT seq
1584 nt
NT seq
+upstream
nt +downstream
nt
atgagcagtgacgacgagcgggacatggcaagaagaccgattcgccgcgcgttgatcagt
gtgtacgacaagaccggcctgattgaacttgcccagggtttgagtgcggcgggtgtcgac
atcgtctcgaccggatcgacggggaaggccattgccggtaaagggattgcggtgacacct
gtggaggaactgaccgggttccccgaggtacttgacggccgggtcaagacattgcaccct
cgggtccatgccggcctgctggccgacttgcgtaaacccgagcatgcctcggagcttgag
caactcggaatcgaggcgttcgaactagttgtcgtcaacttgtatccgttcagccaaacg
gtcgaatccggtgcgactgtagacgaatgtgtcgaacagatcgatactggcggaccttcg
atagtgcgagcggccgcaaagaactatcccagcgtggcggtggtcaccgacccacttggg
tacgttggcgtgcttgccgcagtgcggggcggcggattcacccttgccgagcgtaaaagg
ctggcgtcgatggcatttcagcacatcgtggagtacgacatcgccgtcgctagttggatg
cagtcgacgctagcacccgagcagccaccaacggcgtttccgcagtggtttagccgcagc
tggcgtcgctcggcaatgctgcgctacggcgaaaacccgcaccagcaggcggctctgtac
agcgaccccagtgcctgtcctggcttggctcaggccaagcagctgcacgggaaaaacatg
tcctacaacaacttcactgacgcagacacggcctggcgtgctgccttcgaccacgagcag
tcgtgcgtagcaatcatcaagcacgccaacccgtgcgggattgcaatctcgtcgatttcg
gtcgccgacgcacatcgcaaggctcacgaatgcgacccgttgagtgcctacggcggagtt
atcgccgtcaacaccgaggtcagccttgagatggcagagtacgtgagcaccatcttcacc
gaggtgatcgttgcgccctcctacgcgccaggcgccgtcgacgtgctgacctgcaaaaaa
aacgtccgggtcttggtggcctccgcaccgctacgcggtggtagcgagctacggccggtc
agtggaggactgttgatccagcaacccgatcagcttgacacagcaggtgacaacccagcg
aactggaccttggttaccggatcaccggccggcccggcgacgttgacggacttggtcttt
gcgtggcgtgcctgccgcgcggtgaagtcgaacgcaattgtgatcgccgccaacggcgcc
accatcggtgttggcatgggtcaggttaaccgagtcgacgccgctcgccttgccgttcag
cgtggcggcgaccgggtccgtggcgcagtggtggcctccgatgcgttctttccctttgct
gacggacttcaggcactggccgcggccggagtcacggcgatagtgcaccccgggggttcc
gtgcgtgacgcggaggtaaccgcagctgcagccaaagccggggttactttgtatctcacc
ggagttcgccactttgtgcactag
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