Mycobacterium lepromatosis: MLPF_0276
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Entry
MLPF_0276 CDS
T08064
Symbol
topA
Name
(GenBank) DNA topoisomerase 1
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
mlm
Mycobacterium lepromatosis
Brite
KEGG Orthology (KO) [BR:
mlm00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mlm03032
]
MLPF_0276 (topA)
03400 DNA repair and recombination proteins [BR:
mlm03400
]
MLPF_0276 (topA)
Enzymes [BR:
mlm01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
MLPF_0276 (topA)
DNA replication proteins [BR:
mlm03032
]
Prokaryotic type
DNA Topoisomerases
MLPF_0276 (topA)
DNA repair and recombination proteins [BR:
mlm03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
MLPF_0276 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Toprim_C_rpt
Toprim
Toprim_4
Motif
Other DBs
NCBI-ProteinID:
UKN41589
LinkDB
All DBs
Position
289667..292477
Genome browser
AA seq
936 aa
AA seq
DB search
MSVKGPKGSRSRGNGSRRRLVIVESPTKARKLADYLGSAYIVESSRGHIRDLPRTAADVP
AKFKSEPWARLGVNVYADFEPLYIINPEKKSTVTELKGLLQGADELYLATDGDREGEAIA
WHLIQTLKPRVPVKRMVFHEITEHAILAAAAHPRELDIDLVDAQETRRILDRLYGYEVSP
VLWKKVAPKLSAGRVQSVATRIIVQRERDRMAFCSAAYWDIVAKLDASVSDPTAQPPTFV
ARLTAVNGLRIATGRDFGSLGTLRADCEVSKITVLDDLNATTLAAGLRGAQLTVALAEDK
PYTRRPYPPFMTSTLQQEAGRKLRFSAERTMNIAQRLYENGYITYMRTDSTTLSESAINA
ARTQARQLYGEEYVSESPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRGELDSDEFRIY
ELVWRRTVASQMADAHGTTLSLRIEGRAGEQHVVFSASGSTLTFPGFLKAYVETVDELAG
GEADDAERRLPHLTSGQRLAVIDLTPEGHATNPPARYTEASLVKTLEELGIGRPSTYSSI
IKTIQDRGYVQKKGSALVPSWVAFAVTGLLEQHFGRLVDYHFTAVMEDELDEIATGNEQR
TNWLNNFYFGGNHGMPDSIARSGGLKKLVGVNIEGIDAREVNSIKLFDDAQGRPVYVRLG
KTGPYLERLLAGDDGELTPQRANLKGMLTPDELTLEATEELFATQQEGRFLGVDPETGHE
IVAKDGRYGPYVTEVLPKHDDDDGAADQGSNKGKKASVSQSPKPRTGALLRSMDLQTVTL
EDALKLLLLPRVVGVDPASGEEITVQNGRYGPYLKRGNDSRPLATEDQMFIITLDEALKI
FAEPKRAGRQSASPRPLRELGTDPTSGKPMLIKDGRFGPYVTDGETNAGLRKGDDVVSIT
DERAAELLAERRDRGPVKRTAKKARKIPAKKTAKRS
NT seq
2811 nt
NT seq
+upstream
nt +downstream
nt
atgtcggtgaagggccctaagggctctaggagccgcggaaatgggagtcggcggcgactt
gttatagtcgagtcgccgacgaaagcgcgcaaattggccgactatctaggatctgcgtac
atagtcgagtcatcccgggggcatatccgtgacctgccgcggacggcagccgatgtgccc
gcgaagttcaagtccgagccgtgggctcggctgggcgtaaacgtctacgcagactttgaa
ccgctctacatcatcaaccccgagaagaagagtaccgtcactgaactcaaaggcctgctt
caaggcgccgacgagctctatctggccacagatggtgaccgcgagggcgaagctatcgcc
tggcacctgatacagactctgaaaccgcgagttccggtcaagcggatggttttccacgag
atcaccgaacacgcgatcctcgctgccgctgcgcatccccgtgaactggatatcgacttg
gttgacgcgcaggagacccgacgcatcctggaccggctgtacgggtatgaagttagtccg
gtgctgtggaagaaagtcgcgcctaagctgtcggccggccgcgtgcaatcggtggccacc
cgcatcatcgtgcagcgtgaacgcgatcggatggcgttctgcagcgcagcgtactgggac
attgttgccaagttggacgccagtgtgtccgatccgaccgcccagccgcccaccttcgtc
gcccgtcttacggctgtaaatggcctgcggatcgctaccggccgcgatttcggttcgctg
ggaacgttacgtgcagactgtgaggtctccaaaatcactgtccttgacgacctgaacgca
accacgttggccgcaggattgcgcggcgctcagcttaccgtggcgttagcagaggataag
ccttacactaggcggccgtacccgccattcatgacgtcgacgctgcaacaggaagccgga
cgcaaattgcggttttccgcggaacgcacgatgaacatcgcccagcggctatatgagaac
ggctacatcacctacatgcgtaccgactcgaccactctgtccgagtcggcgatcaacgcc
gctcgtacgcaggcgcgtcagctctacggcgaagagtacgtttctgaatcgccgcgtcag
tacacccgcaaggtaaagaacgcccaggaagcccatgaggccatccggcctgccggcgag
acattcgctactccggacgcggtgcgtggcgaacttgacagtgacgaattccggatctac
gagctggtatggcggcgcacggtagcttcgcagatggccgacgctcacggtactacgctg
agcttgcggatcgagggccgagccggcgagcaacatgttgtcttctcggcttccgggagc
accctgaccttccccggttttcttaaggcctatgtggaaaccgtggacgagctggccggc
ggcgaggctgacgacgctgagcggcgactgccccatctgacctctggtcaacggctggct
gttatcgatctgaccccggaagggcacgctaccaaccctccggcgcgctatactgaagct
tccttggttaaaacgttggaggagttaggtatcggccgtccgtcgacgtactcgtcgata
ataaagaccatccaggaccgcggctacgtacagaagaagggcagcgctctggtgccgtcg
tgggtcgcgtttgctgttaccggtcttttggagcagcatttcggtcgcctcgtcgactac
cacttcaccgcggtgatggaagacgagctcgacgagatcgctaccgggaatgagcaacgc
accaactggctcaacaacttctacttcgggggcaaccacggtatgcccgattcgatagcc
cgctccgggggtttgaagaagttggttggtgtgaatatagaaggcattgatgcacgagag
gtcaactccatcaaactttttgacgatgcgcagggtcgtcctgtctatgttcggctaggc
aagactgggccatatctggaacgcttgttggcaggcgatgatggtgagctcaccccgcag
cgggccaacctcaaaggcatgctcactccggatgagctcaccttggaggctaccgaggag
cttttcgccacacagcaagaggggcgcttcctgggggtggatccagaaactggccacgag
atcgtcgccaaagacggccggtacgggccttatgtgactgaggtcttgcctaagcacgat
gacgacgacggtgcagcggatcagggaagtaataagggtaagaaggcttccgtttctcaa
agtcccaagccgaggaccggggcgttgttgcggagcatggatttgcaaacggtcactctc
gaggatgcgctgaaactgttgttattgcctcgggttgttggcgtggaccctgcttcaggt
gaagagatcaccgtgcagaacgggcgttacggcccatatctgaaacgcggcaacgattct
cgaccactggcaaccgaagaccagatgttcatcatcaccctcgacgaagcgttaaagatc
ttcgctgaaccgaagcgtgctggtagacaaagtgcttcgccgaggccgctgcgtgagctg
gggactgatccgacgtcgggtaagccaatgctaatcaaggacggccggtttggtccgtat
gtcactgacggtgagaccaacgctggcctgcgcaagggtgacgatgtggtgtcgataacc
gatgaacgtgccgccgaattgttggctgaacgacgggaccggggtccggttaaacggact
gctaagaaggctcgcaagatcccggcgaagaagacggccaagcgcagctaa
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