Mycobacterium lepromatosis: MLPF_0768
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Entry
MLPF_0768 CDS
T08064
Symbol
ribBA
Name
(GenBank) bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II
KO
K14652
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:
4.1.99.12
3.5.4.25
]
Organism
mlm
Mycobacterium lepromatosis
Pathway
mlm00740
Riboflavin metabolism
mlm00790
Folate biosynthesis
mlm01100
Metabolic pathways
mlm01110
Biosynthesis of secondary metabolites
mlm01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mlm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00740 Riboflavin metabolism
MLPF_0768 (ribBA)
00790 Folate biosynthesis
MLPF_0768 (ribBA)
Enzymes [BR:
mlm01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.25 GTP cyclohydrolase II
MLPF_0768 (ribBA)
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase
MLPF_0768 (ribBA)
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Paralog
GFIT
Motif
Pfam:
DHBP_synthase
GTP_cyclohydro2
fn3
Motif
Other DBs
NCBI-ProteinID:
UKN41852
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All DBs
Position
752622..753899
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AA seq
425 aa
AA seq
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MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATLEMVAFMVRYTSGYLCAP
LDGAICDRLGLLPMFAVNQDKNGTAYTVTVDARNGVGTGISASDRATTMRLLADPTSVAD
DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGVICEIVSQKDEGSMAQTDE
LRVFADEHDLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYASIYEDVKHVA
LVRGEIAGCSGDGDDVLVRVHSECLTGDVFGSRRCDCGTQLDAAMAMVAREGRGVVLYMR
GHEGRGIGLMHKLQAYQLQDAGADTVDANIKLGFPSDARDYGIGAQILVDLGVRSMRLLT
NNPAKRVGLDGYGLHIIERVPLPVRANADNIRYLMTKRDKMGHDLAGLDDFREPNHFTGE
FGGAL
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgacgaggttggactccgtcgaacgggcggttgctgacattgcggccggtaaagccgtc
atcgtcatcgacgatgaggaccgcgagaacgagggcgacctgatcttcgccgccgaaaag
gcaacgctggagatggtggcctttatggtccgctacacctcgggatacttgtgtgcgccg
ctggacggtgctatctgcgaccggttgggtctgttgccgatgtttgcggtgaatcaagac
aaaaacgggactgcctacacggtcactgtcgacgcgagaaacggtgtaggaacaggtatt
tcggcttctgatcgggctaccacaatgcggttattagctgacccaaccagtgtcgccgac
gatttcactcgccctggccatgtggttccgttgcgcgccaaggacggcggtgtgttgcgc
aggccgggtcatacagaggccgctgtcgacctggcccggctggcgggactccagcccgcg
ggcgtgatctgcgagatcgtcagtcagaaggacgaaggctcgatggcacagaccgacgag
ttgcgggtcttcgctgatgagcatgatctggcgctgatcaccattgccgatctgatcgaa
tggcggcgcaagcatgagaagcacattgagcgggttgctgaagcccggatcccgacccgt
cacggagagtttcgcgctatcggctatgctagtatttacgaggacgttaagcatgtggca
ctggtccgcggcgagattgccggatgcagtggtgacggcgatgacgtattggtgcgggtg
cactccgagtgtttgacgggtgatgtgttcggctcacggcgttgcgattgtgggactcag
ctcgatgccgctatggcgatggtggcgcgagaaggacgcggcgtggtgttatatatgcgt
ggccatgaaggtcgaggtatcgggttgatgcataaactgcaagcttaccagctgcaggac
gctggcgcggacaccgtggatgccaacatcaaactcggatttccttctgatgcaagggat
tacggtattggcgcgcagatattagtcgatctcggagtgcgctcgatgcgattgttgacc
aacaatcccgccaaacgtgttgggctagatgggtacggactgcacatcatcgagcgggtg
ccgcttccggttcgggccaacgcggataacatccgttacttgatgaccaagcgtgacaag
atgggccacgacctggctgggttggatgattttcgtgaaccaaaccattttacaggtgaa
ttcggtggtgctttgtga
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