KEGG   Mycobacterium lepromatosis: MLPF_1034
Entry
MLPF_1034         CDS       T08064                                 
Symbol
nrdE
Name
(GenBank) ribonucleotide-diphosphate reductase subunit alpha
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
mlm  Mycobacterium lepromatosis
Pathway
mlm00230  Purine metabolism
mlm00240  Pyrimidine metabolism
mlm01100  Metabolic pathways
mlm01232  Nucleotide metabolism
Module
mlm_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
mlm_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mlm00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    MLPF_1034 (nrdE)
   00240 Pyrimidine metabolism
    MLPF_1034 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mlm03400]
    MLPF_1034 (nrdE)
Enzymes [BR:mlm01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     MLPF_1034 (nrdE)
DNA repair and recombination proteins [BR:mlm03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    MLPF_1034 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN Asp-B-Hydro_N RNR-II_ins_dom
Other DBs
NCBI-ProteinID: UKN42002
LinkDB
Position
complement(1013471..1015636)
AA seq 721 aa
MPPIATAEPVTGGTHVLFDEKDYHALNAMLNLYDADGKIQFDKDLLAARQFFLQHVNQNT
VFFHNQDEKLDYLIRENYYEREVFDQYSRNFVKSLLDRAYAKKFRFSTFLGAFKYYTSYT
LKTFDGKRYLERLEDRVCVVALTLAAGDTVLAEKLVDEIIDGRFQPATPTFLNSGKKQRG
EPVSCFLLRIEDNMESIGRSVNSALQLSKRGGGVALLLSNIREHGAPIKNIENQSSGVIP
IMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIP
DITFELAKRNEDMYLFSSYDVERVYEVPFADISVTEKYYEMLDDARIRKTKIKAREFFQT
LAELQFESGYPYVMFEDTVNRANPIEGRITHSNLCSEILQVSTPSLFNDDLSYAKVGKDI
SCNLGSLNIAKTMDSPDFAQTVEVAIRALTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMN
LHGYLAREGIFYGSEEGVDFTNIYFYTVLFHVLLASNSIAIERGTFFKGFERSKYASGEF
FDKYIERTWEPKTDKVRQLFARAGIRIPTQNDWKRLKKSVAAHGIYNQNLQAVPPTGSIS
YINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMTNDNLEYYQDAYEIGYQKIIDTYAAA
TQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCM
L
NT seq 2166 nt   +upstreamnt  +downstreamnt
gtgccaccaatcgccactgcagagccggtaaccggcggcactcacgtattgttcgacgaa
aaagactaccatgcgcttaacgcgatgttgaatctgtacgatgcggatggcaagatccag
ttcgacaaggacttactcgcggcccgccaattctttctgcagcatgtcaatcagaatacg
gtctttttccataatcaggacgagaagctggactatctgatccgcgagaattactacgag
cgtgaggtgttcgatcagtactcgcgtaacttcgtcaagtcgctgctggatcgtgcctac
gccaagaagtttcggttctcaacgtttcttggtgcgttcaagtattacacttcttacacg
ctgaagacgttcgacgggaagcggtatctagagcgcctcgaagaccgggtctgcgtggtt
gcactcacgttggcagccggtgacaccgttttagccgagaagctcgtcgacgagattatc
gacggccggttccagccggctaccccgacttttttgaactcaggtaagaagcaacgcggc
gagccggtgagctgttttttgctgcgcatcgaggataacatggagtcgatcgggcgatcg
gtcaactccgcgctacagctatccaagcgtggcgggggagttgctttgctgttgagcaac
attcgtgagcatggtgcaccgatcaagaatatcgaaaaccagtcttccggcgtcattccg
atcatgaagttgcttgaagattcgttctcgtatgccaatcagttgggcgcgcgccaaggc
gccggtgcggtgtacctgcacgcccatcaccctgacatataccgcttcttggacaccaag
cgggagaacgccgatgagaagatccggatcaagacgctgagcctgggggtggtaattccc
gacatcacctttgagctggctaagcgcaacgaggacatgtacctgttctcgtcgtacgat
gtcgaacgggtttacgaggtgccattcgccgatatctcggtgactgagaagtactacgag
atgctcgatgatgcacgcatccgcaagaccaagatcaaggcgcgggagttcttccagacg
ctggccgagctgcagttcgagtccggttacccctatgtcatgttcgaggacacggtgaac
cgggccaaccccattgaaggtaggatcacccactcgaacctgtgctcggagatcttgcag
gtgtctacgccgtcgttgtttaacgacgatttgtcatatgccaaagttggcaaggacatt
tcatgcaacctgggatcgctgaacattgccaagacgatggactcaccggatttcgcgcag
acagttgaggtggcgattcgcgcgctgactgcggtgagtgaccagacgcacattaagtcg
gtgccctcgatcgagcagggtaacaatgattcccatgcgatcgggctagggcagatgaac
ctgcatggctacttggcccgtgaaggcatcttctacggttccgaagagggagtcgatttc
accaatatttacttctatacggtgttgtttcacgtgctgctagcctcgaactctatcgcg
attgaacgaggtacattcttcaagggtttcgagcggtccaagtacgcgtcgggagagttc
ttcgacaaatacatcgaacggacgtgggagccgaagactgacaaagtgcgtcagttgttc
gctagggcagggatccgtatcccgacccaaaacgattggaagcggttgaaaaagtcggtg
gccgcacacggcatctacaaccagaacctacaggcggtgccgccgaccggatcgatctcc
tacatcaaccattcgacgtcgtcgatccacccgatcgtgtcgaaagttgagatccgtaag
gaaggcaaaatcggccgggtttactatccggcgccctatatgaccaatgacaacctggag
tattaccaggacgcttatgagatcgggtaccagaagatcatcgacacatacgcggcggca
acccagcacgtcgaccaagggctctcgttgacgttgttcttcaaagacaccgccaccacc
cgcgacgtgaacaaggcgcagatttatgcgtggcgcaagggaatcaagacgctgtattac
attcggctgcggcagatggcgctggaaggcaccgaggtcgagggctgcgtgtcttgcatg
ctgtag

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