Mycobacterium lepromatosis: MLPF_1163
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Entry
MLPF_1163 CDS
T08064
Symbol
bccA
Name
(GenBank) acetyl-/propionyl-CoA carboxylase subunit alpha
KO
K11263
acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:
6.4.1.2
6.4.1.3
6.4.1.-
6.3.4.14
]
Organism
mlm
Mycobacterium lepromatosis
Pathway
mlm00061
Fatty acid biosynthesis
mlm00074
Mycolic acid biosynthesis
mlm00280
Valine, leucine and isoleucine degradation
mlm00620
Pyruvate metabolism
mlm00630
Glyoxylate and dicarboxylate metabolism
mlm00640
Propanoate metabolism
mlm01100
Metabolic pathways
mlm01110
Biosynthesis of secondary metabolites
mlm01120
Microbial metabolism in diverse environments
mlm01200
Carbon metabolism
mlm01212
Fatty acid metabolism
Module
mlm_M00082
Fatty acid biosynthesis, initiation
mlm_M00741
Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
mlm_M00887
Mycolic acid biosynthesis, meromycolic acid + alpha-carboxyacyl-CoA + trehalose => TMM => TDM/mAGP/GMM
Brite
KEGG Orthology (KO) [BR:
mlm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MLPF_1163 (bccA)
00630 Glyoxylate and dicarboxylate metabolism
MLPF_1163 (bccA)
00640 Propanoate metabolism
MLPF_1163 (bccA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
MLPF_1163 (bccA)
00074 Mycolic acid biosynthesis
MLPF_1163 (bccA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MLPF_1163 (bccA)
Enzymes [BR:
mlm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
MLPF_1163 (bccA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
MLPF_1163 (bccA)
6.4.1.3 propionyl-CoA carboxylase
MLPF_1163 (bccA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Biotin_lipoyl_2
Dala_Dala_lig_C
GARS_A
DUF5817_CT
ATPgrasp_ST
LAL_C2
Peptidase_M23
Motif
Other DBs
NCBI-ProteinID:
UKN42048
LinkDB
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Position
complement(1136516..1138312)
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AA seq
598 aa
AA seq
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MTSHASSRIAKVLVANRGEIAVRVIRAARDARLPSVAVYAEPDAGAPHVRLADEAFALGG
HTSAESYLDFGKILDVAAKSGANAIHPGYGFLAENADFAQAVIDAGLIWIGPSPQSIRDL
GDKVTARHIAARAQAPLVPGTLEPVKNADEVVAFAKEHGVPIAIKAVFGGGGKGMKVART
LEEISELYASAVREATAAFGRGECFVERYLNKPRHVEAQVIADQHGNIVVAGTRDCSLQR
RFQKLVEEAPAPFLTDAQRREIHESAKRICKEARYYGAGTVEYLVGQDGLISFLEVNTRL
QVEHTVTEETTSIDLVLQQFKIANGEKLELTRDPIPRGHAIEFRINGEDAGRNFLPSPGP
VSKFHPPTGPGVRLDSGVETGSVIGGQFDSMLAKLIVHGATRQEALARARRALDEFEVEG
LATVIPFHRAVVSDPALIGDNNSFSVHTRWIETEWNNTIEPFAGSQPHDEKDTRPQQTVV
VEVDGRRLEVSLPADLALANVAGCNPAGVIRKKPKPRKRGIHTGAAVSGDAVTAPMQGTV
VKVAVTEGQKVITGDLVVVLEAMKMENPITAHKNGIITGLAVETGTAITQGAVLAEIK
NT seq
1797 nt
NT seq
+upstream
nt +downstream
nt
gtgaccagtcacgccagctcgaggatcgccaaggttctcgtcgccaaccgcggcgagatt
gctgtccgggtgatccgcgcggctcgcgatgcgaggctgcccagcgtggcggtatacgcc
gagcccgacgccggggcgccacacgtgcggctggccgacgaagcgttcgcgctgggaggt
cacacttccgcagagtcctacctggacttcggtaagatcctcgacgtcgctgcaaaatcc
ggcgccaacgcgatccatcccggttacgggttcctagcagagaatgctgacttcgcccag
gccgtcattgacgccggccttatctggatcggacccagcccacagtcgatccgcgacctc
ggcgacaaggtcaccgcccgccatatcgccgcccgcgcgcaggctccactagtgcccggc
actctggagccggtcaaaaacgctgacgaggtggtggccttcgccaaagaacatggggtg
ccgatcgcgatcaaagccgtcttcggtggcggtggcaagggcatgaaagtggcccgcaca
ctcgaggaaatttccgagctatacgcatcagcggtgcgtgaagccaccgctgcgttcggc
cgcggggaatgtttcgttgagcgctacctcaataagccccgacacgtcgaagcgcaagtg
atcgccgaccagcacgggaacattgtcgtcgccggtactcgggactgctcactacagcgg
cgtttccagaaactggtcgaggaggctccggcgccgttcctgacagacgcccagcgtagg
gaaatccatgaatccgcgaaacggatctgcaaagaggcccgctactacggcgctgggacc
gtagaatacctcgtcggtcaggatggcctaatctcgttcctggaggtcaacacccgcctt
caagttgagcatacggtcaccgaggagaccacaagcatcgacctggtgctgcagcagttt
aagatcgccaacggcgagaagctcgaactaaccagggatcccatcccgcgtggtcacgcc
atcgagttccggatcaatggcgaagacgcaggacgcaactttctgccttcgccggggccg
gtcagcaagttccacccacccaccggccccggcgtgcgattggactccggggtagagacc
ggttcggtaatcggtggccagttcgactccatgcttgccaagctgatcgtgcatggcgcc
actcgccaggaagcactggcgcgcgcccgtcgcgcattggacgaattcgaggtcgaaggc
ctggccacggtcatcccgttccaccgcgctgtggtatccgacccggcgctgatcggcgac
aacaacagcttctcggtgcacacccgctggatcgaaaccgagtggaataacaccatcgaa
cccttcgccggcagccagccccacgacgaaaaggacacccggccacaacagacggtggtc
gtcgaggtcgacggccgccgactcgaggtttcgctgcccgccgatctcgcgttagccaac
gtggccggctgcaatccagccggtgttatccgcaaaaaacccaagccgcgcaagcgaggt
atacacaccggcgcagcggtctccggtgacgcggtgaccgcgcctatgcagggcaccgtg
gtcaaggtcgccgttacggaggggcagaaagtcataacaggagatctggtggtggtcctc
gaagcgatgaagatggagaacccaatcactgcgcataaaaatggtatcatcacggggcta
gcggtcgaaaccggcacggccatcactcaaggcgcggtgctcgccgagatcaagtaa
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