Mycobacterium lepromatosis: MLPF_1376
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Entry
MLPF_1376 CDS
T08064
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mlm
Mycobacterium lepromatosis
Pathway
mlm00300
Lysine biosynthesis
mlm00550
Peptidoglycan biosynthesis
mlm01100
Metabolic pathways
mlm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mlm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MLPF_1376 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MLPF_1376 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MLPF_1376 (murF)
Enzymes [BR:
mlm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MLPF_1376 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UKN42177
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Position
1342606..1344159
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AA seq
517 aa
AA seq
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MIDLTVAQITEIVGGTLVDISPEEATERRVTGSVEFDSRAVVPGGLFLALPGARSDGHDH
AASAIAAGAVAVLAARPVGVPAIVVVPDPRTGDGGLTGVLEHDADGSGAAVLAALAKLAQ
AVAAELVAGGLTIIGITGSSGKTSTKDLVAVVLESLGKVVAPPESFNNELGHPWTVLRAT
RSTDYLILEMSARRPGNIAALAAIAPPTVGVVLNVGTAHLGEFGSRDAIARAKTELPQAI
MQSGVVILNVDDPAVAAMADATAARVIRVSRGSRSDLGSPNSPDVWTGPVSLDELARPRF
TLHTRHPRAGATEIQLGVYGDHQVTNALCAAAVAMECGASVEHVAAALAATGPVSRHRMQ
VTTRADGVTVIDDTYNANPDSMRAGLQALAWIAHGGTHDKNQRGSCARRSWAVLGEMAEL
GEDSIIEHDRIGRLAVRLDVSRLVVVGGGRSINAMHRGAVMEGSWGLDTVNVADPVAALE
LLRAEVRPGDVVLIKASHSVGLGALADVLVGDGAPRP
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atgatcgacctgacggttgcccagattaccgagatcgtcggtggcacgttggtcgatatc
tctcccgaggaggctaccgagcgccgcgtcaccggcagcgtggaattcgattcgcgggct
gttgtccccggcggtctattcctggccttgccgggggcccgctcagacgggcatgaccac
gctgcctcggcgatagcggccggtgcggtcgctgtgttggctgctcggccggtcggcgtt
cccgccatcgtagttgttcctgaccctcgcacgggcgacggcgggctgactggggtgctt
gagcacgatgcagacggatcgggcgcggcggtgctggccgcgttggccaagttggcccag
gcggtggccgcggagttggtagctggcgggctgaccatcattgggattaccggatcgtca
gggaagacgtccaccaaagacttggtggccgtcgtgctggagtcgctcggtaaggtggtg
gcgccgcctgagtcgttcaacaatgaattgggtcatccctggacagtgttgcgtgcaacc
cgtagcacggactatctgattctggagatgtcggcacgtcgtcccggtaatattgccgcg
ttggcggcgatcgctccgccaacggtaggggttgtcctcaacgtcggcactgcgcaccta
ggtgagttcggctcccgggacgccatcgcgcgggctaaaaccgagctgccgcaagctatt
atgcaatccggtgtggtcatactcaacgtcgatgacccggcggtggcggcgatggccgat
gcgaccgcggcccgcgtgattcgggttagtcgcggtagtcgtagcgatctggggtcgcca
aacagcccagacgtttggactggtccggtgtcgctcgacgaacttgctaggccgcgcttc
acgctgcatacgcgacatccgcgcgccggcgccaccgaaatccaactcggcgtgtacggc
gaccaccaggtcaccaacgccttgtgcgcggctgcggtcgcgatggaatgcggcgctagc
gtcgagcacgtggcggctgcgctcgccgcgacggggccggtgtcgcggcatcggatgcag
gtgaccacgcgcgctgacggggtgacggtgatagatgacacctacaacgccaaccccgac
tcgatgcgggccgggctgcaggccctggcttggatcgcgcatggcgggacccatgataag
aaccagcgaggttcctgcgctcgacgaagctgggcggtgttgggtgagatggccgagctt
ggggaggattcgataatcgaacacgatcgcatcggccggctagcggtgcgcttagatgtg
tctcgactcgttgtcgtgggagggggaaggtcgataaacgccatgcaccgcggagcggtt
atggaaggttcgtggggcttagatacggttaacgtggccgaccccgttgctgccctggaa
ttgttgcgggctgaagtacgacctggcgacgtggtcctgatcaaggcgtcgcattcggtc
gggctaggggcgctggctgatgtactggtgggcgacggggccccccgcccatga
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