Mycobacterium lepromatosis: MLPF_1435
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Entry
MLPF_1435 CDS
T08064
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
mlm
Mycobacterium lepromatosis
Pathway
mlm00270
Cysteine and methionine metabolism
mlm00450
Selenocompound metabolism
mlm01100
Metabolic pathways
mlm01110
Biosynthesis of secondary metabolites
mlm01230
Biosynthesis of amino acids
Module
mlm_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mlm00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
MLPF_1435 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
MLPF_1435 (metE)
Enzymes [BR:
mlm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
MLPF_1435 (metE)
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GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
CcFV1_CP
VPS3_C
Motif
Other DBs
NCBI-ProteinID:
UKN42202
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Position
complement(1392681..1394963)
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AA seq
760 aa
AA seq
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MDELVTTQPFTATVTGSPRIGPRRELKRATEGYWARRISRSELESVASTLRRDMWSDLAA
AGLDSVPVNTFSYYDQMLDTAFMLGALPARVTQVSDDLDQYFALARGNDDIEPLEMTKWF
DTNYHYLVPEIEPATTFSLNPDKVLGELKEALEQGIPSRPVVIGPVTFLLLSKGINGGGA
PIQRLEELVGIYCALLSLLAENGARWVQFDEPALVTDLSADAPALAEAVYSALGSVSNRP
AIYVATYFGNPGASLAGLARTPIEAIGIDLVCGADTAVAAVPELAGKTLVAGIVDGRNIW
RTDLESALSKLATLLGSAATVAVSTSCSTLHVPYSLEPETDLDDNLRSWLAFGAEKVAEV
VVLARALRDGRDAVADEIAASNAAVASRRSDSRLHNGQVRARIDSIVASGTHRGDAAQRR
TSQDARLHLPPLPTTTIGSYPQTSAIRKVRAALQAAEIDEAEYISRMKKEVADTIKLQEE
LGLDVLVHGEPERNDMVQYFAEQLDGFFATQNGWVQSYGSRCVRPPILYGDVSRPHPMTI
EWITYAQSLTNKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDETVDLQSAGIA
IIQVDEPALRELLPLRNADQDEYLRWAVRAFRLATSGVADSTQIHTHLCYSEFGEVIEAI
ADLDADVTSIEAARSHMEVLDDLNAVGFANSIGPGVYDIHSPRVPSTDEMAKSLRAALKA
IPMQRLWVNPDCGLKTRSVYEVNASLQNMVAAAHQVRSGT
NT seq
2283 nt
NT seq
+upstream
nt +downstream
nt
atggacgaactcgtgaccactcaaccattcaccgcaaccgtgactggctccccacgcatt
ggcccgcgccgcgaacttaaacgggcgaccgaaggttattgggccagacgtatcagccga
tcagaactggagtccgtcgcctcgacattgcgccgcgacatgtggtcggacttggccgcc
gccggcctggactccgtaccggtaaacaccttctcttactacgaccagatgctcgacacg
gcattcatgctcggcgcgttgcctgcccgggtaacacaagtgtccgacgacctagatcag
tactttgccctagcacgcggaaacgacgacatcgagccgctggagatgactaagtggttc
gacaccaactaccactacctggttcccgagatcgaacccgcaaccaccttctcactgaac
ccggacaaggtactcggtgagctgaaagaagcacttgaacaagggattccgtcccgaccg
gtcgttatagggccggtcaccttcctgttactaagcaagggaattaatggcgggggcgca
ccgatacaacggctcgaagagttggtgggaatctactgcgcgctgctgtcactgcttgcc
gaaaatggcgcacgatgggtgcagttcgacgagccggcgctggttactgatctatccgcc
gatgcgccggcgttagcggaggccgtctacagtgcgctcggctcagttagcaatcgaccc
gccatctacgtggccacttacttcggtaaccccggcgcttccctggcgggactagcccgc
acgcccatcgaggcgatcgggatcgacctcgtctgcggtgccgacacggcggtcgcggcg
gtgcccgagctggccggcaagactctggtggccggcatcgtcgacggacgcaacatctgg
cgcaccgacctagaatcggcgttgagcaagttggcgactctactgggttcagcagccacc
gttgctgtttcgacgtcgtgctctacgctgcatgtaccgtattcgctggaaccagaaacc
gacctggacgacaacttgcgcagctggctggcgttcggcgcggaaaaggtggccgaagtc
gttgtgctggcacgcgcacttcgcgacgggcgcgacgcggtcgccgatgagatcgcggcg
tccaatgccgccgttgcctcgcggcgcagcgactcgcggctgcacaacgggcaggtccgc
gcgcgtattgattcgattgtcgcttccggtacgcaccgcggtgacgcagcacagcgccgc
accagccaggacgcgcgcctacacctgccaccgctgccgaccacgacgatcggctcttac
ccgcagacctcggcgatacgcaaagtgcgcgcggcactgcaggccgctgagatcgacgag
gccgagtacatcagcaggatgaaaaaagaagtcgccgacaccatcaagctgcaggaggaa
ctcgggctagatgtgctggtccatggcgagccagagcgcaacgacatggtacagtatttt
gccgagcagctggacggcttcttcgccacgcagaacggttgggtacagtcctacgggagt
cgttgtgtacgtccaccgatcctctacggcgacgtgtcccggccccacccgatgacaatc
gagtggatcacctacgcgcagtccctgactaacaagccggtgaaagggatgttgaccggt
ccggtcactatcttggcctggtcgtttgttcgtgacgaccagccgctggccgataccgcg
aaccaggtggcactggcgattcgcgatgagaccgtagatctacaatccgccggtatcgca
atcatccaggttgacgagccagcgctacgtgagctgctgccgctgcgtaacgctgatcaa
gacgagtacttacgttgggcggtaagagctttccgcctagctacctcgggtgtcgccgac
tcgacgcagatccacactcatctgtgctattccgagttcggcgaggtgattgaagctatc
gccgacctggatgccgacgtcacatcaatcgaagcggcgcggtcacacatggaggtactg
gacgacctgaacgcggtcggcttcgctaacagcataggcccgggagtctacgacatccac
tcaccgcgggtaccaagcaccgacgagatggccaagtcgcttcgcgcagcattaaaagcc
ataccgatgcaacggctttgggtcaaccccgactgtgggctgaagacccgatcggtttac
gaggtgaacgcgtcgctgcagaacatggtcgcagcagcacaccaggtgcggtcagggacc
taa
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