Mycobacterium lepromatosis: MLPF_1750
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Entry
MLPF_1750 CDS
T08064
Symbol
gcpE
Name
(GenBank) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
KO
K03526
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:
1.17.7.1
1.17.7.3
]
Organism
mlm
Mycobacterium lepromatosis
Pathway
mlm00900
Terpenoid backbone biosynthesis
mlm01100
Metabolic pathways
mlm01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
mlm00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
MLPF_1750 (gcpE)
Enzymes [BR:
mlm01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.7 With an iron-sulfur protein as acceptor
1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
MLPF_1750 (gcpE)
1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
MLPF_1750 (gcpE)
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Paralog
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GFIT
Motif
Pfam:
GcpE
Zn_ribbon_9
ThiG
Zn_ribbon_LysW
Motif
Other DBs
NCBI-ProteinID:
UKN42373
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All DBs
Position
1718055..1719227
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AA seq
390 aa
AA seq
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MRLGMPEAPAPGLAPRRSTRQVMVGSVGVGSDYQISVQSMCITKTHDVNSTLQQIAELTT
AGCDIVRVACPRQEDADALAEIVRHSKIPVIVDIHFQPKYIFAAIDAGCAAVRVNPGNIK
EFDGRVGEVAKAAAAAGIPIRIGVNAGSLDKRFMDKYGKATPEALVESALWEASLFEEHG
FGNIKISVKHHDPVVMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTVKSAVAFGALLSKGI
GDTIRVSLSAPPVEEIKVGNQILESLKLRPRSREIVSCPSCGRAQVDVYKLANEVSAGLD
GLKVPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPEAQIVDTLIEEA
VRLVSKMGVEKSSDHGLETTRSGSPVVTVN
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgcgtctgggcatgcccgaggctccggctcccgggcttgccccccggcgtagcacgcgt
caagtaatggtcggcagcgttggggtcggtagtgactaccagatctccgtgcagtcgatg
tgcatcaccaagacccatgacgtcaactcgacgttgcagcagattgcggagttgaccact
gccggttgtgacatcgttcgggtggcttgcccgcgtcaagaggatgctgacgcacttgct
gaaatcgtccggcacagcaagattccggtgattgtcgacatccacttccagccgaaatac
atctttgccgccattgacgccgggtgtgccgcggtgcgggtcaaccccggcaatatcaaa
gaattcgacggccgggtcggtgaggtcgccaaagccgcggccgcggctggtatcccgatc
cgcatcggcgtcaacgccggctcgctggataagcggtttatggacaagtacggcaaggcc
acacccgaagcactggtggagtccgcactgtgggaggcttcactattcgaagagcacggc
ttcggcaacatcaagatcagcgtcaagcaccacgatcccgtcgttatggtcgccgcctac
gagcaactggccgcccagtgcgactacccattgcacctcggtgtcaccgaagccggtcct
gccttccaaggcaccgtcaagtccgcggtcgcctttggagcactgttgtcgaagggtatc
ggtgacaccatccgagtttcgctatcggcgccgccggtcgaggagatcaaggttggcaac
cagattctcgaatcgctcaaacttcggccgcgttcacgcgagatcgtttcctgcccatcg
tgcggccgtgcgcaggtagacgtctacaagctggccaatgaagtcagcgctggtttggac
ggcctcaaggtgccgctgcgggtcgccgtgatggggtgcgtcgtcaacgggcccggtgag
gcccgcgacgccgacctgggcgtcgcgtccggaaacggcaagggccagatctttgtcaag
ggtgaagtgatcaagactgtacccgaagcccagattgtcgatacgttgatcgaggaggcc
gtgcggcttgtctccaagatgggggtcgagaaaagcagtgatcacggtctagaaacgaca
aggagcggttcaccggttgtgaccgtaaactga
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