Mycobacterium lepromatosis: MLPF_1796
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Entry
MLPF_1796 CDS
T08064
Symbol
hisA
Name
(GenBank) bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase/phosphoribosylanthranilate isomerase PriA
KO
K24017
phosphoribosyl isomerase A [EC:
5.3.1.16
5.3.1.24
]
Organism
mlm
Mycobacterium lepromatosis
Pathway
mlm00340
Histidine metabolism
mlm00400
Phenylalanine, tyrosine and tryptophan biosynthesis
mlm01100
Metabolic pathways
mlm01110
Biosynthesis of secondary metabolites
mlm01230
Biosynthesis of amino acids
Module
mlm_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
mlm00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
MLPF_1796 (hisA)
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
MLPF_1796 (hisA)
Enzymes [BR:
mlm01000
]
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.1 Interconverting aldoses and ketoses, and related compounds
5.3.1.16 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
MLPF_1796 (hisA)
5.3.1.24 phosphoribosylanthranilate isomerase
MLPF_1796 (hisA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
His_biosynth
NMO
Dus
IMPDH
ThiG
DHO_dh
TMP-TENI
Trp_syntA
Aconitase_C
Motif
Other DBs
NCBI-ProteinID:
UKN42396
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Position
1758189..1758923
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AA seq
244 aa
AA seq
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MSLILLPAVDVVKGRAVRLVQGKAGSATEYGSALDVALGWQRDGADWIHLVDLDAAFGRG
SNRDLLAKVVSRLDVQVELSGGIRDDDSLTAALATGCARVNLGTAACENPHWCARVIAEH
GDKVAVGLDVQIVDGQHRLRGRGWETDGGDLWDVLERFDRQGCSRFVVTDVTKDGALGGP
NFDLLASVADRTNVPVIASGGVSSLDDLRAIATLTDRGIEGVIVGTALYAERFTLPQALA
VVRM
NT seq
735 nt
NT seq
+upstream
nt +downstream
nt
atgtcgctgatacttttacccgctgtcgacgtggtcaagggtcgcgccgtgcgcctggtt
cagggaaaggccggtagcgcaaccgagtacggttcagcactggacgtcgcgttgggctgg
caacgtgacggcgccgactggatccatctagtggatctggacgccgcgtttggtcgcggt
tccaaccgcgacctgcttgctaaggtggtgagcagacttgatgtgcaggtcgagttatcc
ggcggtatccgcgatgacgactctctgactgctgcgttggctaccggctgcgcacgggtc
aacctaggtacggccgcatgcgagaacccgcactggtgcgcacgggtgatcgccgagcac
ggtgacaaggttgccgtcggtttggatgtccagatcgtcgacggccagcatcggctgcgc
gggcgtggctgggaaaccgacggcggagacctgtgggacgtgttggaacgctttgatcgc
caaggatgttcacggttcgttgtcaccgatgtcactaaggacggtgcgttgggcggtccc
aacttcgacctgctggcaagtgtcgccgatcgcaccaacgtcccggtgatcgcttccggt
ggcgtttccagcctggacgacctgcgtgccatcgctacgctcaccgaccgcgggatcgag
ggtgtcatcgtgggcacggccctctacgctgaacggttcaccttgccgcaagcactggcc
gtggttcggatgtaa
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