Mycobacterium lepraemurium: MLM_2020
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Entry
MLM_2020 CDS
T05534
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mlp
Mycobacterium lepraemurium
Pathway
mlp00300
Lysine biosynthesis
mlp00550
Peptidoglycan biosynthesis
mlp01100
Metabolic pathways
mlp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mlp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MLM_2020
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MLM_2020
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MLM_2020
Enzymes [BR:
mlp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MLM_2020
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ATA28505
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Position
1979860..1981407
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AA seq
515 aa
AA seq
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MIELTVAQIADILGGTLADITAPDAARRRVTGTVEFDSRAVGPGGLFLALPGARTDGHDH
AEAAVAAGAVAVLAARPVGVPAIVAPPVDAADALAGVFEHDADGSGVAVLAALAKLARAV
AAELVAGGLTIVGITGSSGKTSTKDLVAAVLAPLGEVVAPPGSFNNELGHPWTVLRATAD
TDYLVLEMSARHPGNIAALAEIAPPAVGVVLNVGTAHLGEFGSREAIARTKSELLQAVPA
SGVVVLNVDDPTVAAMAEVTAARVVRVSRAEHTEAGPSDVWAGPVSLDELARPGFTLYHR
HAGGTRQARVQLGVSGDHQAGNALCAAAVALECGATVEQVVAALAGAGPVSRHRMQVSTR
GDGVTVIDDAYNANPDSMRAGLQALAWIARGGAEPSAPARRSWAVLGEMAELGDDAIAEH
DRIGRLAVRLDVFRLVVVGTGRSVSAMHHGAVMEGSWGSADKGAVNVPDAEVALELLRAE
LQPGDVVLVKASNAAGLGALADALARDDSAGGTRR
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagctgaccgtcgcccagatcgccgatatcctcggcggcaccctggccgacatc
accgcaccggacgccgcgcgccggcgcgtcaccggcaccgtcgaattcgactcgcgcgcc
gtcgggcccggcgggttgttcctggcgctgcccggggcgcgcaccgacgggcatgaccac
gcggaggccgcggtggccgccggtgcggtcgccgtgctggccgcccggcccgtcggtgtc
cccgccatcgtcgcgccgccggtggacgccgcggacgcgctggccggggtgttcgagcac
gacgccgacgggtccggtgtcgcggtgctggcggcgctggccaagctggcccgggcggtg
gccgccgagctggtcgccggcgggctgaccatcgtcgggatcaccggatcgtcgggcaag
acgtcgaccaaggacctggtcgcggcggtgctggcgccgctgggtgaggtggtggccccg
cccgggtcgttcaacaacgagctggggcatccctggacggtgctgcgcgccacggccgac
accgactacctggttctcgagatgtcggcgcgccaccccggcaacatcgccgcgctcgcc
gaaatcgccccgccggccgtgggggtggtgctcaacgtcggcaccgcacacctgggcgag
ttcggctcgcgggaagccatcgcacgcaccaaatccgaactgctgcaagcggttccagcg
tccggcgtggtggtcctcaacgtcgacgaccccaccgtggcggccatggccgaggtgact
gcggcccgggtggtcagggtcagccgcgccgagcacaccgaggccggccccagcgacgtg
tgggccgggccggtgtcgctggacgagttggcccggccggggttcacgctgtatcaccgc
cacgccggtgggacacgacaggcgcgggtgcaactcggtgtctccggcgaccaccaggcc
ggcaacgcgctgtgcgcggccgcggttgcgctggagtgcggcgcgacggtcgagcaggtg
gtggccgcgctcgccggggcgggcccggtgtcgcggcaccggatgcaggtcagcacccgc
ggcgatggcgtcacggtgatcgacgacgcctacaacgccaatcccgattcgatgcgggcc
gggctgcaggccctggcctggatcgcccgcggcggggcggaaccgagcgccccggcccgg
cgcagctgggcggtgctgggcgagatggccgaactcggcgacgacgcgatcgccgaacat
gatcgcatcggccggctggcggtgcgcttagatgtgtttcgactcgttgtcgtgggaact
ggaaggtcggtgagcgccatgcaccacggtgcggtcatggagggttcctggggttcggcc
gacaagggagccgtcaacgtgcccgacgccgaggtggcgcttgagctcttgcgggccgag
ctgcagcccggtgacgtggtgttggtcaaggcatccaacgcggccgggctgggcgcactc
gccgacgcgctggcccgtgacgactcagccggcgggacccgccgatga
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